Catalog No.
PHD18801
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human ATP2A2 (Ile315-Met756).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
SERCA2,Calcium pump 2,Sarcoplasmic/endoplasmic reticulum calcium ATPase 2,ATP2B,SR Ca(2+)-ATPase 2,Calcium-transporting ATPase sarcoplasmic reticulum type,slow twitch skeletal muscle isoform,ATP2A2,Endoplasmic reticulum class 1/2 Ca(2+) ATPase
Purification
Purified by antigen affinity column.
Accession
P16615
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Th17-associated cytokines IL-17 and IL-23 in inflamed skin of Darier disease patients as potential therapeutic targets., PMID:37978298
Anti-desmoglein 1 antibody-positive mother and antibody-negative child with Darier's disease., PMID:36074695
Darier Disease Presenting with Recurrent Kaposi Varicelliform Eruption in a 10-year-old Boy with Seborrheic Dermatitis., PMID:36896697
Inactivation of cysteine 674 in the sarcoplasmic/endoplasmic reticulum calcium ATPase 2 causes retinopathy in the mouse., PMID:33848522
Different effects of myotoxins bothropstoxin-I and II from Bothrops snake venom on cation transport ATPases from murine fast twitch skeletal muscle., PMID:26091877
Sarcoplasmic/endoplasmic reticulum Ca2+ ATPase C674 promotes ischemia- and hypoxia-induced angiogenesis via coordinated endothelial cell and macrophage function., PMID:25260714
Malondialdehyde and 4-hydroxynonenal adducts are not formed on cardiac ryanodine receptor (RyR2) and sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA2) in diabetes., PMID:23354458
Immunosuppression decreases inflammation and increases AAV6-hSERCA2a-mediated SERCA2a expression., PMID:22482463
Isoforms of protein 4.1 are differentially distributed in heart muscle cells: relation of 4.1R and 4.1G to components of the Ca2+ homeostasis system., PMID:22429617
Characterizing phospholamban to sarco(endo)plasmic reticulum Ca2+-ATPase 2a (SERCA2a) protein binding interactions in human cardiac sarcoplasmic reticulum vesicles using chemical cross-linking., PMID:22247554
Role of Rac1 in regulation of NOX5-S function in Barrett's esophageal adenocarcinoma cells., PMID:21525435
Cellular prion protein is implicated in the regulation of local Ca2+ movements in cerebellar granule neurons., PMID:21214552
Separate mechanisms cause anemia in ischemic vs. nonischemic murine heart failure., PMID:20032264
Multiple and diverse coexpression, location, and regulation of additional SERCA2 and SERCA3 isoforms in nonfailing and failing human heart., PMID:19962989
Determination of apparent calcium affinity for endogenously expressed human sarco(endo)plasmic reticulum calcium-ATPase isoform SERCA3., PMID:19225163
Angiotensin II-dependent loss of cardiac function: mechanisms and pharmacological targets attenuating this effect., PMID:18528823
Immunohistological study of involucrin expression in Darier's disease skin., PMID:18312435
[Reduced expression of the sarcoplasmic calcium pump SERCA2 in skeletal muscle from patients with chronic obstructive pulmonary disease and low body weight]., PMID:17257557
Ca2+-ATPases in non-failing and failing heart: evidence for a novel cardiac sarco/endoplasmic reticulum Ca2+-ATPase 2 isoform (SERCA2c)., PMID:16402920
Detection of sequence-specific tyrosine nitration of manganese SOD and SERCA in cardiovascular disease and aging., PMID:16399855
Serca isoform expression in the mammalian retina., PMID:15967430
Parallel development of cardiomyocytes and neurons in embryonic stem cell culture., PMID:15894285
Effects of drugs and anticytokine antibodies on expression of ATP2A2 and ATP2C1 in cultured normal human keratinocytes., PMID:15888147
Sarcolipin and phospholamban mRNA and protein expression in cardiac and skeletal muscle of different species., PMID:15801907
Effect of chronic obstructive pulmonary disease on calcium pump ATPase expression in human diaphragm., PMID:15718407
Emerin expression in tubular aggregates., PMID:15085358
Sarco(endo)plasmic reticulum Ca2+ ATPases (SERCA1 and -2) in human extraocular muscles., PMID:14638697
Distribution of SERCA isoforms in human intrafusal fibers., PMID:14574585
Expression of sarco/endo-plasmic reticulum Ca2+-ATPase type 2 isoforms (SERCA2) in normal human skin and mucosa, and Darier's disease skin., PMID:12366411
Role of SERCA2b in mobilization of nuclear Ca2+ in HeLa cells., PMID:12162536
Sarco/endoplasmic reticulum calcium ATPase-2 expression is regulated by ATF6 during the endoplasmic reticulum stress response: intracellular signaling of calcium stress in a cardiac myocyte model system., PMID:11595740
Dissociation of intra- and extracellular domains of desmosomal cadherins and E-cadherin in Hailey-Hailey disease and Darier's disease., PMID:10792220
For research use only. Not for human or drug use.
