Catalog No.
PHD12201
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human NQO1 (Met1-Lys274).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
NAD(P)H:quinone oxidoreductase 1,Azoreductase,Phylloquinone reductase,NQO1,DT-diaphorase,NAD(P)H dehydrogenase [quinone] 1,QR1,DIA4,NMOR1,Quinone reductase 1,Menadione reductase,DTD
Purification
Purified by antigen affinity column.
Accession
P15559
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Therapeutic potential of plasma-treated solutions in atopic dermatitis., PMID:39426754
Molecular hydrogen promotes retinal vascular regeneration and attenuates neovascularization and neuroglial dysfunction in oxygen-induced retinopathy mice., PMID:38915069
Inhibitory effect of rosmarinic acid on IgE-trigged mast cell degranulation in vitro and in vivo., PMID:38270683
Bardoxolone methyl inhibits the infection of rabies virus via Nrf2 pathway activation in vitro., PMID:37950261
Combination Therapy of Lox Inhibitor and Stimuli-Responsive Drug for Mechanochemically Synergistic Breast Cancer Treatment., PMID:37099721
Methamphetamine and HIV-1 Tat proteins synergistically induce microglial autophagy via activation of the Nrf2/NQO1/HO-1 signal pathway., PMID:36162528
Identification of Genes Predicting Poor Response of Trastuzumab in Human Epidermal Growth Factor Receptor 2 Positive Breast Cancer., PMID:35935587
Dual roles of p62/SQSTM1 in the injury and recovery phases of acetaminophen-induced liver injury in mice., PMID:35024307
GRP78 Antibodies Are Associated With Blood-Brain Barrier Breakdown in Anti-Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disorder., PMID:34725263
NQO1 as a Marker of Chemosensitivity and Prognosis for Colorectal Liver Metastasis., PMID:33788750
The effect of Bu Shen Huo Xue Tang on autoimmune premature ovarian insufficiency via Modulation of the Nrf2/Keap1 signaling pathway in mice., PMID:33684516
Si Miao San Attenuates Inflammation and Oxidative Stress in Rats with CIA via the Modulation of the Nrf2/ARE/PTEN Pathway., PMID:33628297
A redox-mediated conformational change in NQO1 controls binding to microtubules and α-tubulin acetylation., PMID:33360352
Zone-specific damage of the olfactory epithelium under protein restriction., PMID:33335225
Prenatal indole-3-carbinol administration activates aryl hydrocarbon receptor-responsive genes and attenuates lung injury in a bronchopulmonary dysplasia model., PMID:33148012
Preliminary Trichinella spiralis Infection Ameliorates Subsequent RSV Infection-Induced Inflammatory Response., PMID:32466130
Placental growth factor regulates the pentose phosphate pathway and antioxidant defense systems in human retinal endothelial cells., PMID:32058040
NF-κB-p62-NRF2 survival signaling is associated with high ROR1 expression in chronic lymphocytic leukemia., PMID:31992855
Curcumin protects against methylmercury-induced cytotoxicity in primary rat astrocytes by activating the Nrf2/ARE pathway independently of PKCδ., PMID:31330227
Sarcodon imbricatus polysaccharides protect against cyclophosphamide-induced immunosuppression via regulating Nrf2-mediated oxidative stress., PMID:30171947
Redox modulation of NQO1., PMID:29298345
Estrogen-Dependent Nrf2 Expression Protects Against Reflux-Induced Esophagitis., PMID:29282639
Soluble P-selectin promotes retinal ganglion cell survival through activation of Nrf2 signaling after ischemia injury., PMID:29144506
Betulinic acid, isolated from the leaves of Syzygium cumini (L.) Skeels, ameliorates the proteinuria in experimental membranous nephropathy through regulating Nrf2/NF-κB pathways., PMID:28711658
Doubly Caged Linker for AND-Type Fluorogenic Construction of Protein/Antibody Bioconjugates and In Situ Quantification., PMID:28524357
p62/SQSTM1 Cooperates with Hyperactive mTORC1 to Regulate Glutathione Production, Maintain Mitochondrial Integrity, and Promote Tumorigenesis., PMID:28512249
Possible Implication of GSTP1 and NQO1 Polymorphisms on Natalizumab Response in Multiple Sclerosis., PMID:27993870
Sulforaphane-induced apoptosis involves the type 1 IP3 receptor., PMID:27528021
Molecular similarity guided optimization of novel Nrf2 activators with 1,2,4-oxadiazole core., PMID:27316545
Repurposing an orally available drug for the treatment of geographic atrophy., PMID:27110092
Abrogation of Nrf2 impairs antioxidant signaling and promotes atrial hypertrophy in response to high-intensity exercise stress., PMID:27048381
Effect of Total Flavone of Haw Leaves on Nuclear Factor Erythroid-2 Related Factor and Other Related Factors in Nonalcoholic Steatohepatitis Rats., PMID:26919834
Short-chain C2 ceramide induces heme oxygenase-1 expression by upregulating AMPK and MAPK signaling pathways in rat primary astrocytes., PMID:26873583
Acupuncture ameliorates cognitive impairment and hippocampus neuronal loss in experimental vascular dementia through Nrf2-mediated antioxidant response., PMID:26546103
Systemic treatment with a 5HT1a agonist induces anti-oxidant protection and preserves the retina from mitochondrial oxidative stress., PMID:26315784
Effect of full flavor and denicotinized cigarettes exposure on the brain microvascular endothelium: a microarray-based gene expression study using a human immortalized BBB endothelial cell line., PMID:26099276
Targeting eIF4GI translation initiation factor affords an attractive therapeutic strategy in multiple myeloma., PMID:24815186
Correlation of Nrf2, NQO1, MRP1, cmyc and p53 in colorectal cancer and their relationships to clinicopathologic features and survival., PMID:24695690
Keap1 inhibition attenuates glomerulosclerosis., PMID:24523358
The Ah receptor recruits IKKα to its target binding motifs to phosphorylate serine-10 in histone H3 required for transcriptional activation., PMID:24519526
Resveratrol prevents suppression of regulatory T-cell production, oxidative stress, and inflammation of mice prone or resistant to high-fat diet-induced obesity., PMID:24176237
Scolopendra subspinipes mutilans attenuates neuroinflammation in symptomatic hSOD1(G93A) mice., PMID:24168240
Antagonistic effects of anti-EMMPRIN antibody when combined with chemotherapy against hypovascular pancreatic cancers., PMID:23836505
Sulforaphane enhances Nrf2 expression in prostate cancer TRAMP C1 cells through epigenetic regulation., PMID:23416117
Induced expression of cytochrome P450 1A and NAD(P)H:quinone oxidoreductase determined at mRNA, protein, and enzyme activity levels in rats exposed to the carcinogenic azo dye 1-phenylazo-2-naphthol (Sudan I)., PMID:23289503
NAD(P)H:quinone oxidoreductase 1 (NQO1) localizes to the mitotic spindle in human cells., PMID:22984577
Inorganic arsenic impairs proliferation and cytokine expression in human primary T lymphocytes., PMID:22683347
Pharmacodynamics of curcumin as DNA hypomethylation agent in restoring the expression of Nrf2 via promoter CpGs demethylation., PMID:21787756
Prognostic significance of NQO1 expression in intrahepatic cholangiocarcinoma., PMID:21577322
[Nrf2 down-regulated cell line H460-N5 with Keap1 over-expression increased sensitivity to anti-cancer drugs]., PMID:20175229
For research use only. Not for human or drug use.
