Catalog No.
PHD08601
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human FABP4 (Met1-Ala132).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Adipocyte-type fatty acid-binding protein,Fatty acid-binding protein 4,ALBP,Adipocyte lipid-binding protein,FABP4,A-FABP,Fatty acid-binding protein,adipocyte,AFABP
Purification
Purified by antigen affinity column.
Accession
P15090
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Identification of Fatty Acid-Binding Protein 4 as a Potential Biomarker and Therapeutic Target for Antineutrophil Cytoplasmic Antibody-Associated Glomerulonephritis., PMID:40098819
Fatty Acid Binding Protein 4 Could Be a Linking Biomarker Between Periodontitis and Systemic Diseases., PMID:40002815
Targeting FABP4/UCP2 axis to overcome cetuximab resistance in obesity-driven CRC with drug-tolerant persister cells., PMID:39823981
Histologic Characterization of Tumor-Adjacent Mammary Adipose Tissue in Normal-Weight and Overweight/Obese Patients with Triple-Negative Breast Cancer., PMID:39456610
Novel FABP4+C1q+ macrophages enhance antitumor immunity and associated with response to neoadjuvant pembrolizumab and chemotherapy in NSCLC via AMPK/JAK/STAT axis., PMID:39353883
An Adipo-Pulmonary Axis Mediated by FABP4 Hormone Defines a Therapeutic Target Against Obesity-Induced Airway Disease., PMID:39071372
Development of a humanized anti-FABP4 monoclonal antibody for potential treatment of breast cancer., PMID:39054536
Macrophages as determinants and regulators of systemic sclerosis-related interstitial lung disease., PMID:38937794
7-MEGA™ inhibits adipogenesis in 3T3-L1 adipocytes and suppresses obesity in high-fat-diet-induced obese C57BL/6 mice., PMID:38909257
Islet-Resident Memory T Cells Orchestrate the Immunopathogenesis of Type 1 Diabetes through the FABP4-CXCL10 Axis., PMID:38884133
Effects of mifepristone on adipocyte differentiation in mouse 3T3-L1 cells., PMID:38553665
Development and verification of a combined immune- and cancer-associated fibroblast related prognostic signature for colon adenocarcinoma., PMID:38312843
Unexpected Crosslinking Effects of a Human Thyroid Stimulating Monoclonal Autoantibody, M22, with IGF1 on Adipogenesis in 3T3L-1 Cells., PMID:36674625
Glomerular expression and urinary excretion of fatty acid-binding protein 4 in IgA nephropathy., PMID:36622635
CD36+ Fibroblasts Secrete Protein Ligands That Growth-Suppress Triple-Negative Breast Cancer Cells While Elevating Adipogenic Markers for a Model of Cancer-Associated Fibroblast., PMID:36361532
mTOR-FABP4 signal is activated in brain arteriovenous malformations in humans., PMID:35876909
FABP4 and I-FABP Levels in Pregnant Women Are Associated with Body Mass Index but Not Gestational Diabetes., PMID:35647197
A hormone complex of FABP4 and nucleoside kinases regulates islet function., PMID:34880500
A-FABP in Metabolic Diseases and the Therapeutic Implications: An Update., PMID:34502295
Proteome profiling of human placenta reveals developmental stage-dependent alterations in protein signature., PMID:34372761
Clozapine Worsens Glucose Intolerance, Nonalcoholic Fatty Liver Disease, Kidney Damage, and Retinal Injury and Increases Renal Reactive Oxygen Species Production and Chromium Loss in Obese Mice., PMID:34206460
Metformin, Macrophage Dysfunction and Atherosclerosis., PMID:34163481
FABP4 deactivates NF-κB-IL1α pathway by ubiquitinating ATPB in tumor-associated macrophages and promotes neuroblastoma progression., PMID:33931964
Fatty acid binding protein 4 promotes autoimmune diabetes by recruitment and activation of pancreatic islet macrophages., PMID:33690220
Fatty-Acid-Binding Protein 4 as a Novel Contributor to Mononuclear Cell Activation and Endothelial Cell Dysfunction in Atherosclerosis., PMID:33287461
Full-length IL-33 regulates Smad3 phosphorylation and gene transcription in a distinctive AP2-dependent manner., PMID:32977155
Identification of B Cell Epitopes of Blo t 13 Allergen and Cross-Reactivity with Human Adipocytes and Heart Fatty Acid Binding Proteins., PMID:31817065
Influence of elevated protein and tannin-rich peanut skin supplementation on growth performance, blood metabolites, carcass traits and immune-related gene expression of grazing meat goats., PMID:31724236
FABP4 levels in hypothyroidism and its relationship with subclinical atherosclerosis., PMID:31651119
Periodontal Pathogens Modulate Lipid Flux via Fatty Acid Binding Protein 4., PMID:31623495
Germ-line genetic variation in the immunoglobulin heavy chain creates stroke susceptibility in the spontaneously hypertensive rat., PMID:31608789
Unconventional Secretion of Adipocyte Fatty Acid Binding Protein 4 Is Mediated By Autophagic Proteins in a Sirtuin-1-Dependent Manner., PMID:31171562
Effects of host fatty acid-binding protein 4 on Eimeria tenella sporozoites invasion of cells., PMID:31069534
Fatty Acid-Binding Protein 4 in Cardiovascular and Metabolic Diseases., PMID:30726793
Circulating Adipocyte Fatty Acid-Binding Protein Concentrations Predict Multiple Mortality Outcomes among Men and Women with Diabetes., PMID:30021923
Adaptive Regulation of Osteopontin Production by Dendritic Cells Through the Bidirectional Interaction With Mesenchymal Stromal Cells., PMID:29910810
Application of adipocyte-related antibodies in undifferentiated sarcomas to identify dedifferentiated liposarcomas based on histological and clinical analysis., PMID:31938337
Isolation and characterization of buffalo (bubalus bubalis) amniotic mesenchymal stem cells derived from amnion from the first trimester pregnancy., PMID:29515060
Inhibition of Endothelial Notch Signaling Impairs Fatty Acid Transport and Leads to Metabolic and Vascular Remodeling of the Adult Heart., PMID:29353241
Ectopic Fatty Acid-Binding Protein 4 Expression in the Vascular Endothelium is Involved in Neointima Formation After Vascular Injury., PMID:28903937
Dermal Lipogenesis Inhibits Adiponectin Production in Human Dermal Fibroblasts while Exogenous Adiponectin Administration Prevents against UVA-Induced Dermal Matrix Degradation in Human Skin., PMID:27428951
Invariant NKT Cell Activation Induces Late Preterm Birth That Is Attenuated by Rosiglitazone., PMID:26740111
Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes., PMID:26702093
Docosahexaenoic Acid Modulates a HER2-Associated Lipogenic Phenotype, Induces Apoptosis, and Increases Trastuzumab Action in HER2-Overexpressing Breast Carcinoma Cells., PMID:26640797
ZnO Nanoparticles Upregulates Adipocyte Differentiation in 3T3-L1 Cells., PMID:26271306
Generation of human adipose stem cells through dedifferentiation of mature adipocytes in ceiling cultures., PMID:25867041
High ω-3:ω-6 fatty acids ratio increases fatty acid binding protein 4 and extracellular secretory phospholipase A2IIa in human ectopic endometrial cells., PMID:25709631
The mAb against adipocyte fatty acid-binding protein 2E4 attenuates the inflammation in the mouse model of high-fat diet-induced obesity via toll-like receptor 4 pathway., PMID:25596549
Secretion of fatty acid binding protein aP2 from adipocytes through a nonclassical pathway in response to adipocyte lipase activity., PMID:25535287
Fatty acid binding protein 4 expression in cerebral vascular malformations: implications for vascular remodelling., PMID:24865546
For research use only. Not for human or drug use.
