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Anti-C6 Polyclonal Antibody

Catalog #:   PHC99701 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: P13671
Overview

Catalog No.

PHC99701

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human C6 (Gln682-Ala934).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Complement component C6,C6

Purification

Purified by antigen affinity column.

Accession

P13671

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Various lysates were subjected to SDS PAGE followed by western blot with C6 antibody (PHC99701) at 1μg/ml.

    Lane 1: Human plasma lysate

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 105 kDa
    Observed MW: 105 kDa
  • Immunohistochemical
    Immunohistochemical analysis of human prostate stained for C6 with PHC99701.
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with C6 antibody (PHC99701) at 1 µg/ml.

    Lane 1: Recombinant Protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 31 kDa
    Observed MW: 31 kDa
References

Targeting PERP promotes anti-tumor immunity in HNSCC by regulating tumor immune microenvironment and metabolic homeostasis., PMID:40483487

Clinical canine Borrelia burgdorferi (sensu lato) infections are associated with highly elevated total IgG ELISA titers and convalescent Th2 immune responses., PMID:40476072

Spatiotemporal prevalence and characterization of the lineage I insect-specific flavivirus, Quang Binh virus, isolated from Culex gelidus mosquitoes in Singapore., PMID:40455069

Ficolin-3 Activates Complement and Triggers Necroptosis in Cholangiocarcinoma Cells via the RIPK1/RIPK3/MLKL Signaling Pathway., PMID:40407231

Borrelia burgdorferi Strain-Specific Differences in Mouse Infectivity and Pathology., PMID:40333117

The "H sign" in MOGAD myelitis., PMID:40327177

Diagnostic validation of novel Borrelia antigens discovered by whole-proteome microarray: Advancing early detection and test of cure for Lyme disease., PMID:40315844

Potential of Ultrashort Pulsed Electric Fields to Disrupt Dense Structure in Glioma Tumors., PMID:40305246

B lymphocyte subset-based stratification in primary Sjögren's syndrome: implications for lymphoma risk and personalized treatment., PMID:40295463

The Protective Effects and Immunological Responses Induced by a Carboxymethyl Cellulose Microcapsule-Coated Inactivated Vaccine Against Largemouth Bass Ranavirus (LMBRaV) in Largemouth Bass (Micropterus salmoides)., PMID:40266084

The ability of an oral combination of afoxolaner, moxidectin and pyrantel to protect dogs from Borrelia burgdorferi infections transmitted by Ixodes scapularis., PMID:40259302

The voltage-gated sodium channel β3 subunit modulates C6 glioma cell motility independently of channel activity., PMID:40245999

A novel anti-C6 based approach for IgG avidity testing in Lyme borreliosis: A proof-of-concept study., PMID:40188988

Insect-specific virus platforms for arbovirus vaccine development., PMID:40160816

Development of a virulent O'nyong'nyong challenge model to determine heterologous protection mediated by a hydrogen peroxide-inactivated chikungunya virus vaccine., PMID:40096126

A Refined Human Linear B Cell Epitope Map of Outer Surface Protein C (OspC) From the Lyme Disease Spirochete, Borrelia Burgdorferi., PMID:40017585

Clinical Trial to Assess the Safety and Tolerability of Anti-IL 23 Monoclonal Antibody Guselkumab in Patients With Alcohol-Associated Liver Disease., PMID:39949265

Affinity Maturation for Antibody Engineering: The Critical Role of Residues on CDR Loops of Antibodies in Antigen Binding., PMID:39942636

Development and application of UHPLC-MS/MS method to quantify eculizumab in PNH patients., PMID:39938137

A 73-Year-Old Man Presenting with Shoulder Muscle Pain and a Diagnosis of Guillain-Barré Syndrome., PMID:39923125

Akabane virus isolated from biting midges and its infection in local domestic animal, Yunnan, China: a field and laboratory investigation., PMID:39897479

Characterization of the colostrum proteome of primiparous Holstein cows and its association with colostrum immunoglobulin G concentrations., PMID:39833978

[Identification and Analysis of Irregular Antibodies in Hospitalized Patients Prepared to Accept Blood Transfusion]., PMID:39743278

Newcastle Disease Vaccination Program in Broilers Using an Apathogenic Heat-Resistant Vaccine., PMID:39736953

Early in vitro results indicate that de-O-acetylated sialic acids increase Selectin binding in cancers., PMID:39717751

Ivermectin Inhibits Zika Virus Replication in Vitro But Does Not Prevent Zika Virus Infection in Rhesus Macaques (Macaca mulatta)., PMID:39689359

Longitudinal Analysis of Binding Antibody Levels Against 39 Human Adenovirus Types in Sera from 60 Regular Blood Donors from Greifswald, Germany, over 5 Years from 2018 to 2022., PMID:39599861

Twenty Years of Lyme Borreliosis in the Netherlands: Temporal Trends in Seroprevalence and Risk Factors., PMID:39597574

Exploring flavonoids as potent SLC46A3 inhibitors: Insights from the structural characteristics of flavonoid-SLC46A3 interactions., PMID:39579794

A promise of nose to brain delivery of bevacizumab intranasal sol-gel formulation substantiated in rat C6 glioma model., PMID:39417842

Ficolin-3 induces apoptosis and suppresses malignant property of hepatocellular carcinoma cells via the complement pathway., PMID:39357793

Characteristics of anti-contactin1 antibody positive autoimmune nodopathies combined with membranous nephropathy., PMID:39317078

Genetic characteristics of human parainfluenza viruses 1-4 associated with acute lower respiratory tract infection in Chinese children, during 2015-2021., PMID:39264196

Preclinical Evidence for the Protective Capacity of Antibodies Induced by Lyme Vaccine Candidate VLA15 in People., PMID:39233712

A chimeric vaccine derived from Australian genotype IV Japanese encephalitis virus protects mice from lethal challenge., PMID:39085247

Epilepsia Partialis Continua as a manifestation of aquaporin-4 autoimmunity., PMID:39077880

Anti-HNA testing of allo-exposed COVID-19 convalescent plasma donors including genetic human neutrophil antigen screening to prevent anti-HNA antibody-mediated transfusion-related acute lung injury., PMID:39044618

One-step detection of procollagen type III N-terminal peptide as a fibrosis biomarker using fluorescent immunosensor (quenchbody)., PMID:39030019

Positive effect of ulnar nerve fascicle transfer to musculocutaneous nerve seeded with allogeneic adipose tissue derived stem cells on nerve regeneration for repairing upper brachial plexus injury in a rat model: A preliminary study., PMID:39012167

Rapid immunochemical methods for the analysis of proquinazid in strawberry QuEChERS extracts., PMID:38980331

Affinity-matured antibody with a disulfide bond in H-CDR3 loop., PMID:38909835

Dengue virus transmission risk in blood donation: Evidence from Thailand., PMID:38818789

What is the role of complement in bystander hemolysis? Old concept, new insights., PMID:38708453

Immune response kinetics to SARS-CoV-2 infection and COVID-19 vaccination among nursing home residents-Georgia, October 2020-July 2022., PMID:38625908

Population pharmacokinetics and exposure-response analyses of polatuzumab vedotin in patients with previously untreated DLBCL from the POLARIX study., PMID:38622879

Humanization of a mouse anti-human complement C6 monoclonal antibody as a potential therapeutic for certain complement-mediated diseases., PMID:38598870

Prolonged SARS-CoV-2 T Cell Responses in a Vaccinated COVID-19-Naive Population., PMID:38543904

A validated LC-MS/MS method for the quantitation of daratumumab in rat serum using rapid tryptic digestion without IgG purification and reduction., PMID:38447348

A robust and validated LC-MS/MS method for the quantification of ramucirumab in rat and human serum using direct enzymatic digestion without immunoassay., PMID:38266611

Identification of patient endotypes and adalimumab treatment responders in axial spondyloarthritis using blood-derived extracellular matrix biomarkers., PMID:38199849

Datasheet

Document Download

Anti-C6 Polyclonal Antibody.pdf

 

$ 170
Product specifications
50 μg 170 100 μg 280

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Anti-C6 Polyclonal Antibody [PHC99701]
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