Catalog No.
PHB04401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human HUS1 (Met1-Ser280).
Applications
ELISA, IHC, WB
Recommended Dilution
| Application |
Dilution |
| ELISA |
1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000 |
Target
Checkpoint protein HUS1, hHUS1, HUS1
Purification
Purified by antigen affinity column.
Accession
O60921
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Note
For research use only.
Binding to native proteins by antipeptide monoclonal antibodies., PMID:1993848
Molecular analysis of hus1+, a fission yeast gene required for S-M and DNA damage checkpoints., PMID:9180692
Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin., PMID:11799063
Expression of DNA damage checkpoint protein Hus1 in epithelial ovarian tumors correlates with prognostic markers., PMID:18156970
ATR and Rad17 collaborate in modulating Rad9 localisation at sites of DNA damage., PMID:19020305
The RAD9-RAD1-HUS1 (9.1.1) complex interacts with WRN and is crucial to regulate its response to replication fork stalling., PMID:22002307
RPA-Binding Protein ETAA1 Is an ATR Activator Involved in DNA Replication Stress Response., PMID:27818175
Identification and characterization of a novel nuclear structure containing members of the homologous recombination and DNA damage response pathways., PMID:30553479