Catalog No.
PHC89901
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human SCGB1A1/Uteroglobin (Glu22-Asn91).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Clara cells 10 kDa secretory protein,CC10,UP-1,Uteroglobin,SCGB1A1,UP1,UGB,CCSP,Clara cell phospholipid-binding protein,Urine protein 1,Secretoglobin family 1A member 1,CCPBP,Urinary protein 1
Purification
Purified by antigen affinity column.
Accession
P11684
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Circulating CC16, immune response to Mycoplasma pneumoniae and lung function: a population-based, multi-cohort study., PMID:40090526
Dupilumab efficacy in relation to changes in club cell secretory protein 16., PMID:40043947
Respiratory long COVID in aged hamsters features impaired lung function post-exercise with bronchiolization and fibrosis., PMID:40021627
The impact of tangeretin combined with whey protein on exercise-induced bronchoconstriction in professional athletes: a placebo-controlled trial., PMID:39422600
Clara cell 10 (CC10) protein attenuates allergic airway inflammation by modulating lung dendritic cell functions., PMID:39078462
Detection of serum CC16 by a rapid and ultrasensitive magnetic chemiluminescence immunoassay for lung disease diagnosis., PMID:39072498
A rapid point of care CC16 kit for screening of occupational silica dust exposed workers for early detection of silicosis/silico-tuberculosis., PMID:34873200
Bimodal fibrosis in a novel mouse model of bleomycin-induced usual interstitial pneumonia., PMID:34728556
A decline in club cell secretory proteins in lung transplantation is associated with release of natural killer cells exosomes leading to chronic rejection., PMID:34627707
Club Cell Protein 16 Attenuates CD16brightCD62dim Immunosuppressive Neutrophils in Damaged Tissue upon Posttraumatic Sepsis-Induced Lung Injury., PMID:33575362
Clinical significance of CC16 and IL-12 in bronchoalveolar lavage fluid of various stages of silicosis., PMID:33302652
Early local neutralization of CC16 in sepsis‑induced ALI following blunt chest trauma leads to delayed mortality without benefitting overall survival., PMID:33125155
Decline in Club Cell Secretory Proteins, Exosomes Induction and Immune Responses to Lung Self-antigens, Kα1 Tubulin and Collagen V, Leading to Chronic Rejection After Human Lung Transplantation., PMID:32890135
Club cell protein 16 in sera from trauma patients modulates neutrophil migration and functionality via CXCR1 and CXCR2., PMID:31666007
High-mobility group box-1 protein from CC10+ club cells promotes type 2 response in the later stage of respiratory syncytial virus infection., PMID:30407867
Imaging Lymphatics in Mouse Lungs., PMID:30242759
Nasal epithelium injury by chlorination products and other stressors predicts persistent sensitization to aeroallergens in young schoolchildren., PMID:28628840
Progression of EGFR-Mutant Lung Adenocarcinoma is Driven By Alveolar Macrophages., PMID:27496865
Postnatal development of the bronchiolar club cells of distal airways in the mouse lung: stereological and molecular biological studies., PMID:26796206
Examining the Effects of External or Internal Radiation Exposure of Juvenile Mice on Late Morbidity after Infection with Influenza A., PMID:26114328
Phosphorylation of p300 increases its protein degradation to enhance the lung cancer progression., PMID:24530506
Inhibition of the αvβ6 integrin leads to limited alteration of TGF-α-induced pulmonary fibrosis., PMID:24508732
EGF shifts human airway basal cell fate toward a smoking-associated airway epithelial phenotype., PMID:23818594
Interleukin-25 induces pulmonary arterial remodeling via natural killer T cell-dependent mechanisms., PMID:23711862
Nasal epithelium biomarkers in young children: associations with allergic sensitization and environmental stressors., PMID:23169618
Alleviation of lung inflammatory responses by adeno-associated virus 2/9 vector carrying CC10 in OVA-sensitized mice., PMID:23013277
Nasal epithelium integrity, environmental stressors, and allergic sensitization: a biomarker study in adolescents., PMID:22424574
Respiratory effects associated with wood fuel use: a cross-sectional biomarker study among adolescents., PMID:21901861
[Expression of serum Clara cell secretory protein 10 in wheezing children under 5 years old]., PMID:21426635
The CC16 A38G polymorphism is associated with the development of asthma in children with allergic rhinitis., PMID:21255142
Bleomycin revisited: towards a more representative model of IPF?, PMID:20675435
The mouse forkhead gene Foxp2 modulates expression of the lung genes., PMID:20553735
The effects of overexpression of histamine releasing factor (HRF) in a transgenic mouse model., PMID:20552026
Identification and characterization of Ch806 mimotopes., PMID:20544195
Prognostic significance of OCT4 expression in adenocarcinoma of the lung., PMID:20462980
[Effects of airborne fine particulate matters on human immunological indicators]., PMID:20364588
Human LPLUNC1 is a secreted product of goblet cells and minor glands of the respiratory and upper aerodigestive tracts., PMID:20237794
Clara cell 10-kD protein suppresses chitinase 3-like 1 expression associated with eosinophilic chronic rhinosinusitis., PMID:20093645
Strain-dependent activation of NF-kappaB in the airway epithelium and its role in allergic airway inflammation., PMID:19897746
Generation of lung epithelial-like tissue from human embryonic stem cells., PMID:19891764
Amylase expression in taste receptor cells of rat circumvallate papillae., PMID:19408014
Distribution and regulation of protein expression of the free fatty acid receptor GPR120., PMID:19145429
Secretoglobin 1A1 gene and asthma pre-disposition: what is the evidence?, PMID:19128350
Effect of infliximab on local and systemic inflammation in chronic obstructive pulmonary disease: a pilot study., PMID:18277064
Munc13-2-/- baseline secretion defect reveals source of oligomeric mucins in mouse airways., PMID:18258655
Immunohistochemical localization of cystic fibrosis transmembrane regulator and clara cell secretory protein in taste receptor cells of rat circumvallate papillae., PMID:18156603
Haemophilus influenzae lysate induces aspects of the chronic obstructive pulmonary disease phenotype., PMID:18096867
Pneumoproteins as markers of paraquat lung injury: a clinical case., PMID:17174135
Mesenchymal maintenance of distal epithelial cell phenotype during late fetal lung development., PMID:17114281
Secretory cells of the airway express molecules of the chemoreceptive cascade., PMID:17024421
For research use only. Not for human or drug use.
