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Anti-CETP Polyclonal Antibody

Catalog #:   PHC89701 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: P11597
Overview

Catalog No.

PHC89701

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CETP (Ile81-Ala311).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

CETP,Lipid transfer protein I,Cholesteryl ester transfer protein

Purification

Purified by antigen affinity column.

Accession

P11597

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with CETP antibody (PHC89701) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 28 kDa
    Observed MW: 28 kDa
References

Immunotherapy and vaccine-based approaches for atherosclerosis prevention: a systematic review study., PMID:40114074

Efficacy of a novel PCSK9 inhibitory peptide alone and with evinacumab in a mouse model of atherosclerosis., PMID:39909173

Recent advances in immunotherapy targeting CETP proteins for atherosclerosis prevention., PMID:39907207

Vaccination as a Promising Approach in Cardiovascular Risk Mitigation: Are We Ready to Embrace a Vaccine Strategy?, PMID:39766344

A novel LPS binding /bactericidal permeability-increasing protein (LBP/BPI) from the scallop Argopecten purpuratus plays an essential role in host resistance to Vibrio infection., PMID:39471964

The effect of dulaglutide on glycated hemoglobin is associated with PNPLA3 Ι148Μ gene polymorphism in patients with type 2 diabetes mellitus., PMID:39179734

Advances in targeting LDL cholesterol: PCSK9 inhibitors and beyond., PMID:39070027

Role of CETP, PCSK-9, and CYP7-alpha in cholesterol metabolism: Potential targets for natural products in managing hypercholesterolemia., PMID:38866219

The importance of LDL-C lowering in atherosclerotic cardiovascular disease prevention: Lower for longer is better., PMID:38576462

Complex changes in serum protein levels in COVID-19 convalescents., PMID:38396092

CETP-derived Peptide Seq-1, the Key Component of HB-ATV-8 Vaccine Prevents Stress Responses, and Promotes Downregulation of Pro-Fibrotic Genes in Hepatocytes and Stellate Cells., PMID:38301446

Two decades of vaccine development against atherosclerosis., PMID:37860053

Obicetrapib plus ezetimibe as an adjunct to high-intensity statin therapy: A randomized phase 2 trial., PMID:37277261

Intensive cholesterol-lowering treatment reduces synovial inflammation during early collagenase-induced osteoarthritis, but not pathology at end-stage disease in female dyslipidemic E3L.CETP mice., PMID:36898656

Plasma Proteome Profiling of Patients With In-stent Restenosis by Tandem Mass Tag-Based Quantitative Proteomics Approach., PMID:35265678

A single-dose, implant-based, trivalent virus-like particle vaccine against "cholesterol checkpoint" proteins., PMID:34541299

Biological drug and drug delivery-mediated immunotherapy., PMID:33996408

Novel high-intensive cholesterol-lowering therapies do not ameliorate knee OA development in humanized dyslipidemic mice., PMID:33722697

Beneficial effects of brown fat activation on top of PCSK9 inhibition with alirocumab on dyslipidemia and atherosclerosis development in APOE*3-Leiden.CETP mice., PMID:33667684

Novel role of cholesteryl ester transfer protein (CETP): attenuation of adiposity by enhancing lipolysis and brown adipose tissue activity., PMID:33166579

Genome-Wide Association Study Highlights APOH as a Novel Locus for Lipoprotein(a) Levels-Brief Report., PMID:33115273

No effects of PCSK9-inhibitor treatment on spatial learning, locomotor activity, and novel object recognition in mice., PMID:32858115

The lipid transfer properties of CETP define the concentration and composition of plasma lipoproteins., PMID:32591337

Development of an effective liposomal cholesterol ester transfer protein (CETP) vaccine for protecting against atherosclerosis in rabbit model., PMID:31852350

Alirocumab, evinacumab, and atorvastatin triple therapy regresses plaque lesions and improves lesion composition in mice., PMID:31843957

Heterozygous Ldlr-Deficient Hamster as a Model to Evaluate the Efficacy of PCSK9 Antibody in Hyperlipidemia and Atherosclerosis., PMID:31779098

Oncostatin M reduces atherosclerosis development in APOE*3Leiden.CETP mice and is associated with increased survival probability in humans., PMID:31461490

Anti-PCSK9 antibodies inhibit pro-atherogenic mechanisms in APOE*3Leiden.CETP mice., PMID:31366894

Antisense Oligonucleotides Targeting Lipoprotein(a)., PMID:31111240

Therapeutic Intranasal Vaccine HB-ATV-8 Prevents Atherogenesis and Non-alcoholic Fatty Liver Disease in a Pig Model of Atherosclerosis., PMID:30792163

Drugs that Mimic the Effect of Gene Mutations for the Prevention or the Treatment of Atherosclerotic Disease: From PCSK9 Inhibition to ANGPTL3 Inactivation., PMID:30306859

Achieved LDL cholesterol levels in patients with heterozygous familial hypercholesterolemia: A model that explores the efficacy of conventional and novel lipid-lowering therapy., PMID:29934068

From lipid locus to drug target through human genomics., PMID:29800275

Targeted delivery of CD44s-siRNA by ScFv overcomes de novo resistance to cetuximab in triple negative breast cancer., PMID:29777999

Cholesteryl ester transfer protein and its inhibitors., PMID:29487091

The AT04A vaccine against proprotein convertase subtilisin/kexin type 9 reduces total cholesterol, vascular inflammation, and atherosclerosis in APOE*3Leiden.CETP mice., PMID:28637178

Investigational therapies for hypercholesterolemia., PMID:28368771

A novel atheroprotective role of MF59-like adjuvant when co-administered with CETP vaccine in rabbit model of atherosclerosis., PMID:28096968

New directions for pharmacotherapy in the treatment of acute coronary syndrome., PMID:27677394

Polyhedral 3D structure of human plasma very low density lipoproteins by individual particle cryo-electron tomography1., PMID:27538822

Anti-atherosclerosis effect of different doses of CETP vaccine in rabbit model of atherosclerosis., PMID:27261627

Cholesteryl ester transfer between lipoproteins does not require a ternary tunnel complex with CETP., PMID:26876146

Promising new therapies for the treatment of hypercholesterolemia., PMID:26822080

Low High-Density Lipoprotein and Risk of Myocardial Infarction., PMID:26692765

Non-statin Treatments for Managing LDL Cholesterol and Their Outcomes., PMID:26548322

Higher Cardiovascular Risk in Common Variable Immunodeficiency and X-Linked Agammaglobulinaemia Patients., PMID:26183722

Current Treatment of Dyslipidemia: Evolving Roles of Non-Statin and Newer Drugs., PMID:26169307

Discovery Approaches for Novel Dyslipidemia Drugs., PMID:26135857

Prevention of fatal hepatic complication in schistosomiasis by inhibition of CETP., PMID:26060442

Modification of CETP function by changing its substrate preference: a new paradigm for CETP drug design., PMID:25616437

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-CETP Polyclonal Antibody [PHC89701]
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