Catalog No.
PHC87901
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PIM1 (Ser98-Lys313).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
PIM1,Serine/threonine-protein kinase pim-1
Purification
Purified by antigen affinity column.
Accession
P11309
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
[Relapse-related candidate genes and their clinicopathological connections of diffuse large B cell lymphoma]., PMID:40159024
Diagnosis, Prognosis, and Treatment of Triple-Negative Breast Cancer: A Review., PMID:40124876
Zanubrutinib plus R-CHOP for the treatment of newly diagnosed double-expressor lymphoma: A phase 2 clinical study., PMID:39748728
Novel approaches in myelofibrosis., PMID:39670187
Efficacy and Safety of Polatuzumab Vedotin Plus Rituximab, Cyclophosphamide, Doxorubicin and Prednisone for Previously Untreated Diffuse Large B-Cell Lymphoma: A Real-World, Multi-Center, Retrospective Cohort Study., PMID:39641321
Pim1 is Critical in T-cell-independent B-cell Response and MAPK Activation in B Cells., PMID:39505064
[Efficacy and safety analysis of the OR-CHOP regimen for the treatment of MCD subtype diffuse large B cell lymphoma in the real-world setting]., PMID:39414605
PIM1/NF-κB/CCL2 blockade enhances anti-PD-1 therapy response by modulating macrophage infiltration and polarization in tumor microenvironment of NSCLC., PMID:39004633
In silico studies and development of a protein-based electrochemical sensor for selective and sensitive detection of aflatoxin B1., PMID:38935329
Transcriptomic signatures of classical monocytes reveal pro-inflammatory modules and heterogeneity in polyarticular juvenile idiopathic arthritis., PMID:38835762
Deciphering the Prognostic Significance of MYD88 and CD79B Mutations in Diffuse Large B-Cell Lymphoma: Insights into Treatment Outcomes., PMID:38643457
Mutational, immune microenvironment, and clinicopathological profiles of diffuse large B-cell lymphoma and follicular lymphoma with BCL6 rearrangement., PMID:38462571
Leukemic presentation and progressive genomic alterations of MCD/C5 diffuse large B-cell lymphoma (DLBCL)., PMID:37730436
Mutant PIK3CA as a negative predictive biomarker for treatment with a highly selective PIM1 inhibitor in human colon cancer., PMID:37621144
IGH 3'RR recombination uncovers a non-germinal center imprint and c-MYC-dependent IGH rearrangement in unmutated chronic lymphocytic leukemia., PMID:37496419
[Clinicopathologic characteristics and prognostic analysis of testicular diffuse large B-cell lymphoma]., PMID:37357002
Transcriptomic analysis of neutrophil apoptosis induced by diffuse large B-cell lymphoma unveils a potential role in neutropenia., PMID:37266765
Molecular Biomarker Exploration of Rituximab plus CHOP Therapy in Real-World Diffuse Large B-Cell Lymphoma Patients., PMID:36649512
Inhibition of PIM Kinases in DLBCL Targets MYC Transcriptional Program and Augments the Efficacy of Anti-CD20 Antibodies., PMID:34625423
Autoantibodies in the diagnosis, prognosis, and prediction of colorectal cancer., PMID:34528528
Hypoxia-activated platelets stimulate proliferation and migration of pulmonary arterial smooth muscle cells by phosphatidylserine/LOX-1 signaling-impelled intercellular communication., PMID:34520855
c-MYC and p53 expression highlight starry-sky pattern as a favourable prognostic feature in R-CHOP-treated diffuse large B-cell lymphoma., PMID:34374220
Crystal Structure-Guided Design of Bisubstrate Inhibitors and Photoluminescent Probes for Protein Kinases of the PIM Family., PMID:34299628
Gene expression in circulating tumor cells reveals a dynamic role of EMT and PD-L1 during osimertinib treatment in NSCLC patients., PMID:33504904
Targeting PRAS40: a novel therapeutic strategy for human diseases., PMID:33504218
Proposal and validation of a method to classify genetic subtypes of diffuse large B cell lymphoma., PMID:33479306
Molecular profiling of Chinese R-CHOP treated DLBCL patients: Identifying a high-risk subgroup., PMID:32399964
Cytotoxicity Assessment and Apoptosis-related Gene Profiling of Antibody Treated Acute Myeloid Leukemia (AML) and Acute Lymphocytic Leukemia (ALL) Cancerous Cell Lines., PMID:32245312
Targeting of inflammatory pathways with R2CHOP in high-risk DLBCL., PMID:32139889
Phosphorylation of DEPDC5, a component of the GATOR1 complex, releases inhibition of mTORC1 and promotes tumor growth., PMID:31548394
Pim-1 as a Therapeutic Target in Lupus Nephritis., PMID:30791224
Targeting PIM Kinase with PD1 Inhibition Improves Immunotherapeutic Antitumor T-cell Response., PMID:30327305
Analysis of Genomic Alteration in Primary Central Nervous System Lymphoma and the Expression of Some Related Genes., PMID:30227305
From Waldenström's macroglobulinemia to aggressive diffuse large B-cell lymphoma: a whole-exome analysis of abnormalities leading to transformation., PMID:28841204
Bonafide Targets of Deregulated microRNAs in Non-Small Cell Lung Cancer as Tool to Identify Novel Therapeutic Targets: A Review., PMID:27719642
CD95-mediated apoptosis in Burkitt's lymphoma B-cells is associated with Pim-1 down-regulation., PMID:27641442
Development of a novel multiplex beads-based assay for autoantibody detection for colorectal cancer diagnosis., PMID:26915739
Human CD180 Transmits Signals via the PIM-1L Kinase., PMID:26555723
Patterns and Significance of PIM Kinases in Urothelial Carcinoma., PMID:26551340
The mutational pattern of primary lymphoma of the central nervous system determined by whole-exome sequencing., PMID:25189415
EBNA3C augments Pim-1 mediated phosphorylation and degradation of p21 to promote B-cell proliferation., PMID:25121590
PRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling., PMID:24909179
Characterisation of seven newly established head and neck squamous cell carcinoma cell lines., PMID:24792014
RNAi screen identifies a synthetic lethal interaction between PIM1 overexpression and PLK1 inhibition., PMID:24771642
Integrative biology approach identifies cytokine targeting strategies for psoriasis., PMID:24523322
Inhibition of IL-17 as a pharmacological approach for IBD., PMID:23886112
Detection of neutralizing antibodies to erythropoietin by inhibition of rHuEPO-stimulated EGR1 gene expression in the UT-7/EPO cell line., PMID:23142458
Phosphorylation of the androgen receptor by PIM1 in hormone refractory prostate cancer., PMID:22986532
Inhibition of Pim-1 attenuates the proliferation and migration in nasopharyngeal carcinoma cells., PMID:22840454
Identification of a phenanthrene derivative as a potent anticancer drug with Pim kinase inhibitory activity., PMID:21981263
For research use only. Not for human or drug use.
