Catalog No.
PHC87501
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human BCR (Lys174-Asp331).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Renal carcinoma antigen NY-REN-26,BCR1,BCR,D22S11,Breakpoint cluster region protein
Purification
Purified by antigen affinity column.
Accession
P11274
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Patterns of adjuvant bone modifying agent use in patients with early-stage breast cancer in the United States., PMID:40500761
Imprints of somatic hypermutation on B-cell receptor immunoglobulins post-infection versus post-vaccination against SARS-CoV-2., PMID:40489958
Synergy and antagonism in the integration of BCR and CD40 signals that control B-cell population expansion., PMID:40473841
MBD2 promotes B cell differentiation and BCR signaling in systemic lupus erythematosus by regulating the LEF-1-PTEN-PI3K axis., PMID:40467564
Microfluidics combined with electron microscopy for rapid and high-throughput mapping of antibody-viral glycoprotein complexes., PMID:40461656
Sialylated IgG expressed in triple-negative breast cancer cells promotes cancer progression by promoting glycolysis., PMID:40457370
CEACAM1 as a mediator of B-cell receptor signaling in mantle cell lymphoma., PMID:40436855
B-cell lymphoma: Advances in pathogenesis, diagnosis, and targeted therapies., PMID:40435909
Differentiation-dependent EBF1 Activity Determines CD22 Transcription and Leukemia Sensitivity to Inotuzumab Ozogamicin., PMID:40435412
Dual generation of stereo- and linear-specific monoclonal antibodies through B-cell receptors by DNA and cell immunization for therapeutic applications., PMID:40412732
Extracellular Inosine Induces Anergy in B Cells to Alleviate Autoimmune Hepatitis., PMID:40409684
B cell receptor silencing reveals origin and dependencies of high-grade B cell lymphomas with MYC and BCL2 rearrangements., PMID:40402557
Intra-tumoral spatial heterogeneity in breast cancer quantified using high-dimensional protein multiplexing and single cell phenotyping., PMID:40399910
B-cell immune repertoire sequencing in tobacco cigarette smoking, vaping, and chronic obstructive pulmonary disease in the COPDGene cohort., PMID:40386772
Single cell transcriptomics correlate avian coronavirus prime vaccination efficacy with antigen-presenting cell preference., PMID:40382358
Adult Acute Lymphoblastic Leukemia: 2025 Update on Diagnosis, Therapy, and Monitoring., PMID:40377367
Molecular characterization and predictors of relapse in patients with Ph + ALL after frontline ponatinib and blinatumomab., PMID:40369607
Dasatinib Pharmacokinetics and Advanced Nanocarrier Strategies: from Systemic Limitations to Targeted Success., PMID:40360939
Insertional diversification of the immunoglobulin heavy chain in chronic lymphoproliferative disorders., PMID:40356055
[Application of next-generation sequencing technology for the investigation of immunoglobulin variable region characteristics and their prognostic significance in patients with chronic lymphocytic leukemia]., PMID:40355356
Antigen mobility regulates the dynamics and precision of antigen capture in the B cell immune synapse., PMID:40354540
Denosumab as an immune modulator in HER2-negative early breast cancer: results of the window-of-opportunity D-BIOMARK clinical trial., PMID:40350430
Chimeric autoantibody receptor T cells clonally eliminate B cells producing autoantibodies against IFN-γ., PMID:40344086
The Quest for Antibodies and Other Acquired Immune Receptors: A Historical Perspective., PMID:40341816
Somatic hypermutation generates antibody specificities beyond the primary repertoire., PMID:40339575
Naive and Memory B Cell BCR Repertoires in Individuals Immunized with an Inactivated SARS-CoV-2 Vaccine., PMID:40333337
The evolving therapeutic revolution in adult acute lymphoblastic leukemia., PMID:40323723
Induced B cell receptor diversity predicts PD-1 blockade immunotherapy response., PMID:40314973
Regulatory T cell epitope content in human antibodies decreases during maturation., PMID:40313951
Management of Adult Acute Lymphoblastic Leukemia: A Review., PMID:40310617
Impact of memory T cells on SARS-CoV-2 vaccine response in hematopoietic stem cell transplant., PMID:40294012
Monoclonal antibodies derived from B cells in subjects with cystic fibrosis reduce Pseudomonas aeruginosa burden in mice., PMID:40272253
Efficient boosting of Omicron-reactive memory B cells after breakthrough infection protects from repeated exposure., PMID:40264792
Critical roles of chronic BCR signaling in the differentiation of anergic B cells into age-associated B cells in aging and autoimmunity., PMID:40249819
Disease-specific B cell clones are shared between patients with Crohn's disease., PMID:40246842
Reading of human acute immune dynamics in omicron SARS-CoV-2 breakthrough infection., PMID:40231451
Decoding B Cells in Autoimmune Diseases Through ScRNA + BCR-Seq: Current Knowledge and Future Directions., PMID:40214492
Pharmacovigilance study of adverse reactions of anti-HER-2 drugs for the treatment of HER-2-positive breast cancer based on the FAERS database., PMID:40205546
Blinatumomab in combination with olverembatinib and concurrent intrathecal chemotherapy successfully treated a chronic myeloid leukemia relapse with central nervous system blast crisis: case report and literature review., PMID:40202540
Myeloid-Driven Immune Suppression Subverts Neutralizing Antibodies and T Cell Immunity in Severe COVID-19., PMID:40183283
Glofitamab in refractory or relapsed diffuse large B cell lymphoma after failing CAR-T cell therapy: a phase 2 LYSA study., PMID:40181090
A ROR1 targeted bispecific T cell engager shows high potency in the pre-clinical model of triple negative breast cancer., PMID:40165319
CRISPR screens with trastuzumab emtansine in HER2-positive breast cancer cell lines reveal new insights into drug resistance., PMID:40165206
Supervised fine-tuning of pre-trained antibody language models improves antigen specificity prediction., PMID:40163503
Immunotherapy followed by cetuximab in locally advanced/metastatic cutaneous squamous cell carcinomas: the I-TACKLE trial., PMID:40154210
Impact of Protein Kinase C Activation and Monoclonal Antibodies on Immune Checkpoint Regulation and B Cell Function in Patients with Chronic Lymphocytic Leukemia., PMID:40149717
CHIKV mRNA vaccines encoding conserved structural/envelope proteins confer broad cross-lineage protection against infection., PMID:40148284
Lung-resident memory B cells maintain allergic IgE responses in the respiratory tract., PMID:40139187
B-cell depletion therapy reduces retinal inflammation in experimental autoimmune uveoretinitis., PMID:40117810
Activated polyreactive B cells are clonally expanded in autoantibody positive and patients with recent-onset type 1 diabetes., PMID:40117290
For research use only. Not for human or drug use.
