Catalog No.
PHC82001
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CTSA (Asp215-Met470).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
CTSA,Lysosomal protective protein,Protective protein cathepsin A,Cathepsin A,Carboxypeptidase L,Protective protein for beta-galactosidase,PPGB,Carboxypeptidase C,PPCA
Purification
Purified by antigen affinity column.
Accession
P10619
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Transcriptomic signatures in peripheral CD4+T-lymphocytes may reflect melanoma staging and immunotherapy responsiveness prior to ICI initiation., PMID:40226614
MOG35 - 55-induced EAE model of optic nerve inflammation compared to MS, MOGAD and NMOSD related subtypes of human optic neuritis., PMID:40197321
Impact of Low Hepatitis Delta Virus Screening Rates on the Accurate Estimation of Seroprevalence in Florida: A Retrospective Observational Study., PMID:40125109
Concerning Safety and Efficacy of Concurrent and Consolidative Durvalumab With Thoracic Radiation Therapy in PDL1-Unselected Stage III Non-Small Cell Lung Cancer: Brief Report., PMID:39147210
Neutralizing IFN-γ autoantibodies are rare and pathogenic in HLA-DRB1*15:02 or 16:02 individuals., PMID:38470480
Garetosmab in fibrodysplasia ossificans progressiva: a randomized, double-blind, placebo-controlled phase 2 trial., PMID:37770652
Patients With Inflammatory Bowel Diseases and Higher Visceral Adipose Tissue Burden May Benefit From Higher Infliximab Concentrations to Achieve Remission., PMID:37207314
Leveraging CTSA hubs for rapid, large-scale, high-impact research: A case study during a global public health emergency., PMID:36755544
Insights on 21 Years of HBV Surveillance in Blood Donors in France., PMID:36423116
Anti-nucleocapsid antibody levels and pulmonary comorbid conditions are linked to post-COVID-19 syndrome., PMID:35801588
Equivalent Cellular and Humoral Immunity to Varicella Zoster Virus in Patients With Inflammatory Bowel Disease and Healthy Older Adults for Whom Immunization Is Recommended., PMID:35060934
An outbreak of SARS-CoV-2 on a transplant unit in the early vaccination era., PMID:34969164
Breakthrough COVID-19 after SARS-CoV-2 vaccination in solid organ transplant recipients: An analysis of symptomatic cases and monoclonal antibody therapy., PMID:34932874
Monoclonal antibody treatment for COVID-19 in solid organ transplant recipients., PMID:34787345
IL-6 receptor blockade does not slow β cell loss in new-onset type 1 diabetes., PMID:34747368
Serum Samples from Co-Infected and Domestic Cat Field Isolates Nonspecifically Bind FIV and Other Antigens in Enzyme-Linked Immunosorbent Assays., PMID:34071706
Immune Responses to SARS-CoV-2 in Solid Organ Transplant Recipients., PMID:33688459
Association of Pulmonary Hemorrhage, Positive Proteinase 3, and Urinary Red Blood Cell Casts With Venous Thromboembolism in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis., PMID:31216123
Assessing the efficacy of new biologic therapies in hidradenitis suppurativa: consistency vs. bias in outcome measures in moderate and severe disease., PMID:30875132
Factors at de novo donor-specific antibody initial detection associated with allograft loss: a multicenter study., PMID:30597643
Pegloticase in gout treatment - safety issues, latest evidence and clinical considerations., PMID:29204266
Analysis of Transfusion-Related Acute Lung Injury and Possible Transfusion-Related Acute Lung Injury Reported to the French Hemovigilance Network From 2007 to 2013., PMID:28864336
Recent progress in development of transgenic silkworms overexpressing recombinant human proteins with therapeutic potential in silk glands., PMID:26971553
Soluble IgM links apoptosis to complement activation in early alcoholic liver disease in mice., PMID:26922040
[Assessment of malaria screening management in blood donation control in the French Military Blood Institute]., PMID:24948206
Egg-white-specific IgA and IgA2 antibodies in egg-allergic children: is there a role in tolerance induction?, PMID:24118158
IgE, but not IgG4, antibodies to Ara h 2 distinguish peanut allergy from asymptomatic peanut sensitization., PMID:23094689
Autoimmune diseases and autoantibodies in the first degree relatives of patients with systemic sclerosis., PMID:20223638
Heightened endoplasmic reticulum stress in the lungs of patients with chronic obstructive pulmonary disease: the role of Nrf2-regulated proteasomal activity., PMID:19797762
A randomized, double-blinded, placebo-controlled multicenter trial of etanercept in the treatment of alcoholic hepatitis., PMID:18848937
Elastogenesis in cultured dermal fibroblasts from patients with lysosomal beta-galactosidase, protective protein/cathepsin A and neuraminidase-1 deficiencies., PMID:16538002
[Comparison of techniques used to screen blood donations for malaria antibodies]., PMID:15077420
Identification of a CTL4/Neu1 fusion transcript in a sialidosis patient., PMID:12067718
Analysis of the C-terminal structure of urinary Tamm-Horsfall protein reveals that the release of the glycosyl phosphatidylinositol-anchored counterpart from the kidney occurs by phenylalanine-specific proteolysis., PMID:11741296
GGAs: a family of ADP ribosylation factor-binding proteins related to adaptors and associated with the Golgi complex., PMID:10747089
A family of proteins with gamma-adaptin and VHS domains that facilitate trafficking between the trans-Golgi network and the vacuole/lysosome., PMID:10747088
High density O-glycosylation on tandem repeat peptide from secretory MUC1 of T47D breast cancer cells., PMID:10373415
Protective protein/cathepsin A loss in cultured cells derived from an early-infantile form of galactosialidosis patients homozygous for the A1184-G transition (Y395C mutation)., PMID:9636645
Transport of human lysosomal neuraminidase to mature lysosomes requires protective protein/cathepsin A., PMID:9501080
Fetal diagnosis of galactosialidosis (protective protein/cathepsin A deficiency)., PMID:9437536
Protective protein in the bovine lysosomal beta-galactosidase complex., PMID:9357958
Lysosomal protective protein/cathepsin A. Role of the "linker" domain in catalytic activation., PMID:7592859
Protective protein as an endogenous endothelin degradation enzyme in human tissues., PMID:7822272
Distribution of lysosomal protective protein in human tissues., PMID:7999052
Human lysosomal protective protein has cathepsin A-like activity distinct from its protective function., PMID:1907282
The gene encoding human protective protein (PPGB) is on chromosome 20., PMID:2071143
Human placental neuraminidase. Activation, stabilization and association with beta-galactosidase and its protective protein., PMID:3922758
A human serum protein system affecting muscle contractility: characterization of the five components and their reaction sequence., PMID:670311
Effects of coupled tumor specific antigens (CTSA) on the growth of transplanted tumors in C3 H/HEJ mice., PMID:62331