Catalog No.
YHF24901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser58-Gly141
Predicted molecular weight
23.35 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P58012
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
FOXL2, Forkhead box protein L2
Note
For research use only.
A computational analysis of the molecular mechanisms underlying the effects of ibuprofen and dibutyl phthalate on gene expression in fish., PMID:38845962
Human Genetics of Ventricular Septal Defect., PMID:38884729
Landscape of potential germline pathogenic variants in select cancer susceptibility genes in patients with adult-type ovarian granulosa cell tumors., PMID:38898688
Role of ERβ in the ovary and ovary related diseases., PMID:38906392
FOXO1 induced fatty acid oxidation in hepatic cells by targeting ALDH1L2., PMID:38923573
Insights into the role of FoxL2 in tebuconazole-induced male- biased sex differentiation of zebrafish., PMID:38977095
Comparable to 17α- methyl testosterone, dietary supplements of Tribulus terrestris and Mucuna pruriens promote the development of mono-sex, all-male tilapia fry, growth, survival rate and sex-related genes (Amh, Sox9, Foxl2, Dmrt1)., PMID:39026327
miR-34 negatively regulates the expression of Dmrt and related genes in the testis of mud crab Scylla paramamosain., PMID:39128537
Pathological characteristics of SRY-negative 38,XX-DSD pigs: A family case report., PMID:39190944
Characterization and expression patterns of the Fox gene family under heat and cold stress in Manila clam Ruditapes philippinarum based on genome-wide identification., PMID:39216278
Discovery of a proteolysis targeting chimera (PROTAC) as a potent regulator of FOXP3., PMID:39222889
pSTAT3 activation of Foxl2 initiates the female pathway underlying temperature-dependent sex determination., PMID:39226347
foxl2l is a germ cell-intrinsic gatekeeper of oogenesis in zebrafish., PMID:39257375
Association of FOXL2 and ERCC6 variants with premature ovarian insufficiency and their potential use in clinical IVF guidance., PMID:39277148
Zebrafish Foxl2l functions in proliferating germ cells for female meiotic entry., PMID:39341446
Identification, expression, and function analysis of Rbpms2 splicing variants in Japanese flounder gonad., PMID:39414089
Computational insights into irinotecan's interaction with UBE2I in ovarian and endometrial cancers., PMID:39476484
Long Noncoding RNAs Expressed in Mouse Pituitary Development and Mature Hormone-Producing Cells., PMID:39487735
A Transcriptional Signature of Induced Neurons Differentiates Virologically Suppressed People Living With HIV from People Without HIV., PMID:39484396
Ovarian Sex Cord-Stromal Neoplasms: An Overview of Molecular Events and How to Correlate Morphology With Molecular Findings., PMID:39492459
Defects in meiosis I contribute to the genesis of androgenetic hydatidiform moles., PMID:39545410
Transcriptomic analysis of melatonin on the mechanism of embryonic gonadal development in female Jilin white geese., PMID:39566171
Early ovarian differentiation in the tammar wallaby and the effects of exposure to bisphenol A., PMID:39569971
The Molecular Landscape of 227 Adult Granulosa Cell Tumors of the Ovary: Insights into the Progression from Primary to Recurrence., PMID:39615884
[Small cell carcinoma of the ovary of hypercalcaemic type: a clinicopathological analysis of sixteen cases]., PMID:39648003
Gain-of-Function Chromatin Remodeling Activity of Oncogenic FOXL2C134W Reprograms Glucocorticoid Receptor Occupancy to Drive Granulosa Cell Tumors., PMID:39652611
Foxo1 directs the transdifferentiation of mouse Sertoli cells into granulosa-like cells., PMID:39681193
Ovarian Adult Granulosa Cell Tumors: A Scoping Review of DNA Alterations and Their Known Significance., PMID:39740818
Complex immunohistochemical and molecular study on 5 cases of ovarian juvenile granulosa cell tumors reveals a consistent alteration in the PI3K/AKT/mTOR signaling pathway., PMID:39773640
A novel CUL4B gene variant activating Wnt4/β-catenin signal pathway to karyotype 46, XY female with disorders of sex development., PMID:39773765
FOXL2 Knockdown Inhibits the Progression of Endometriosis., PMID:39776079
CRISPR targeting of FOXL2 c.402C>G mutation reduces malignant phenotype in granulosa tumor cells and identifies anti-tumoral compounds., PMID:39776254
Sex determination factor, a novel male-linked gene in the sea cucumber Apostichopus japonicus: Molecular characterization, expression patterns and effects of gene knockdown., PMID:39778676
Protective effect of luteinizing hormone on frozen-thawed ovarian follicles and granulosa cells., PMID:39808671
A Dynamic Shift in Estrogen Receptor Expression During Granulosa Cell Differentiation in the Ovary., PMID:39834231
Molecular Characterization and Expression of unc-13d in the Sex Reversal of Monopterus albus., PMID:39858121
Dose-dependent role of AMH and AMHR2 signaling in male differentiation and regulation of sex determination in Spotted knifejaw (Oplegnathus punctatus) with X1X1X2X2/X1X2Y chromosome system., PMID:39893368
Unveiling the role of FOXL2 in female differentiation and disease: a comprehensive review†., PMID:39976382
Epigenetic Perspectives and Their Prognostic Value in Early Recurrence After Hepatocellular Carcinoma Resection., PMID:40075616
FOXL2 drives the differentiation of supporting gonadal cells in early ovarian development., PMID:40102860
Effects of Huluan decotion on cyclophosphamide-induced autoimmune premature ovarian failure in murine models., PMID:40151113
Regulation of FOXL2 gene in ovarian granulosa cell tumor by JNK inhibitor., PMID:40204754
An inducible FOXL2-dependent mouse model of ovarian adult type granulosa cell tumor., PMID:40221170
Functional analysis of a novel FOXL2 mutation in blepharophimosis, ptosis, and epicanthus inversus syndrome type II and elucidation of the genotype-phenotype correlation., PMID:40251640
An Inducible CYP19A1 Excision Model for Sexual Differentiation in Chicken (Gallus gallus) via the CRISPR/Cas9 System., PMID:40284798
Spatiotemporal and single-cell atlases to dissect regional specific cell types of the developing ovary., PMID:40461746
A novel variant in the MAP3K1 genomic locus reveals abnormal cell apoptosis as a potential pathogenic mechanism in 46, XY disorders of sex development., PMID:40476564
Ontogeny of RSPO1, FOXL2, and RUNX1 during ovarian differentiation in the marsupial tammar wallaby., PMID:40481762
Genome-Wide Identification and Expression Analysis of Zona Pellucida (ZP) Gene Family in Cynoglossus semilaevis., PMID:40508155
H3K9me3 Involved in FOXL2 Regulation of SerpinE2 Expression to Affect Steroid Hormone Synthesis in Follicular Granulosa Cells., PMID:40512073
For research use only. Not for human or drug use.
