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Anti-CTSH Polyclonal Antibody

Catalog #:   PHC42801 Specific References (43) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: P09668
Overview

Catalog No.

PHC42801

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CTSH (Ala23-Val335).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

CPSB,Pro-cathepsin H,CTSH

Purification

Purified by antigen affinity column.

Accession

P09668

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with CTSH antibody (PHC42801) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 37 kDa
    Observed MW: 37 kDa
References

Longitudinal assessment of thyroid function in dogs with hypoadrenocorticism: Clinical outcomes and prevalence of autoantibodies., PMID:39531378

Concentration of non-myocyte proteins in arterial media of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy., PMID:36753487

Longitudinal Pattern of First-Phase Insulin Response Is Associated With Genetic Variants Outside the Class II HLA Region in Children With Multiple Autoantibodies., PMID:31591105

Genetic Variants Predisposing Most Strongly to Type 1 Diabetes Diagnosed Under Age 7 Years Lie Near Candidate Genes That Function in the Immune System and in Pancreatic β-Cells., PMID:31558544

A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic dermatitis., PMID:27913303

Regulation of split anergy in natural killer cells by inhibition of cathepsins C and H and cystatin F., PMID:26247631

Preliminary study of thyroid and colon cancers-associated antigens and their cognate autoantibodies as potential cancer biomarkers., PMID:22612312

Increased expression of cathepsins and obesity-induced proinflammatory cytokines in lacrimal glands of male NOD mouse., PMID:20463324

Identification, expression and immunolocalization of cathepsin B3, a stage-specific antigen expressed by juvenile Fasciola gigantica., PMID:19632187

Thyroid testing in Sloughis., PMID:18681922

[Thyroid crisis and protein C deficiency in a case of superior sagittal sinus thrombosis]., PMID:17370653

Serum thyroid hormone concentrations and thyroglobulin autoantibodies in trained and non-trained healthy whippets., PMID:16772138

Inhibitory p41 isoform of invariant chain and its potential target enzymes cathepsins L and H in distinct populations of macrophages in human lymph nodes., PMID:15196205

Expression of cathepsin H in differentiating rat spermatids: immunoelectron microscopic study., PMID:12838426

Gene expression analysis of human middle ear cholesteatoma using complementary DNA arrays., PMID:12792315

[Clinical, hematological, biochemical and endocrinological aspects of 32 dogs with hypothyroidism]., PMID:12741092

Cysteine protease activity is required for surfactant protein B processing and lamellar body genesis., PMID:12495934

Cathepsin expression in oral squamous cell carcinoma: relationship with clinicopathologic factors., PMID:12029284

Canine thyrotropin beta-subunit gene: cloning and expression in Escherichia coli, generation of monoclonal antibodies, and transient expression in the Chinese hamster ovary cells., PMID:10869856

Identification of peptide fragments generated by digestion of bovine and human osteocalcin with the lysosomal proteinases cathepsin B, D, L, H, and S., PMID:9076588

Enzyme-linked immunosorbent assay for the detection of total cathepsin H in human tissue cytosols and sera., PMID:9050938

Expression and the role of cathepsin H in human glioma progression and invasion., PMID:8640738

Biochemical and immunohistochemical analysis of cathepsins B, H, L and D in human melanocytic tumours., PMID:7598531

Purification and characterization of cathepsin H from hepatopancreas of carp Cyprinus carpio., PMID:1499287

Incorporation and degradation by kidney lysosomes of cystatin alpha injected intravenously., PMID:1555593

Bacteriologic monitoring of periodontal diseases: cultural, enzymatic, immunologic, and nucleic acid studies., PMID:1912631

Use of BANA hydrolysis as a diagnostic test for identifying periodontopathic environments., PMID:1792543

Properties and nature of a cysteine proteinase inhibitor located in keratohyalin granules of rat epidermis., PMID:2199217

Immunocytochemical localization of cathepsins B and H in corticotrophs and melanotrophs of rat pituitary gland., PMID:2159033

Determination of cathepsins B and H in sera and synovial fluids of patients with different joint diseases., PMID:2329322

Inhibition of tumor growth, invasion and metastasis in papain-immunized mice., PMID:2139872

Immunocytochemical localization of angiotensinogen and cathepsins B, H, and L in rat hepatocytes, with special reference to degradation of angiotensinogen in lysosomes after colchicine., PMID:2685113

Immunocytochemical localization of prorenin, renin, and cathepsins B, H, and L in juxtaglomerular cells of rat kidney., PMID:2509552

[Application of neuronal cell culture in human degenerative brain disorders]., PMID:2486604

Immunocytochemical localization of cathepsins B, H, L, and T4 in follicular cells of rat thyroid gland., PMID:2703704

Immunohistochemical and biochemical study of a cathepsin B-like proteinase in human colonic cancers., PMID:3180094

Immunolocalization of cathepsins B, H and L in skeletal muscle of X-linked muscular dystrophy (mdx) mouse., PMID:3279718

Cathepsin D, B, and H in rat brain as demonstrated by immunohistochemistry., PMID:3122502

Abnormal increases of lysosomal cysteinine proteinases in rimmed vacuoles in the skeletal muscle., PMID:3511718

Antibodies to rat liver cathepsins: characterization and use for the identification of enzyme precursors., PMID:3579871

Distribution of cathepsins B and H in rat tissues and peripheral blood cells., PMID:3900059

Homologous radioimmunoassay for canine thyrotropin: response of normal and x-irradiated dogs to propylthiouracil., PMID:7460852

Identification and possible regulation of muscle cell lysosomal protease activity by exogenous protease inhibitors., PMID:7043996

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-CTSH Polyclonal Antibody [PHC42801]
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