Structure of natural killer receptor 2B4 bound to CD48 reveals basis for heterophilic recognition in signaling lymphocyte activation molecule family. PMID: 17950006
Growth factor independence 1 (Gfi1) regulates cell-fate decision of a bipotential granulocytic-monocytic precursor defined by expression of Gfi1 and CD48. PMID: 23226623
NMR analysis of interacting soluble forms of the cell-cell recognition molecules CD2 and CD48. PMID: 8634239
Molecular cloning and biological characterization of NK cell activation-inducing ligand, a counterstructure for CD48. PMID: 10556801
Costimulation by CD48 and B7-1 induces immunity against poorly immunogenic tumors. PMID: 8627175
Human cell-adhesion molecule CD2 binds CD58 (LFA-3) with a very low affinity and an extremely fast dissociation rate but does not bind CD48 or CD59. PMID: 7520278
Mast cells and eosinophils in allergy: Close friends or just neighbors. PMID: 26526347
Repopulating activity of ex vivo-expanded murine hematopoietic stem cells resides in the CD48-c-Kit+Sca-1+lineage marker- cell population. PMID: 18079432
SHIP influences signals from CD48 and MHC class I ligands that regulate NK cell homeostasis, effector function, and repertoire formation. PMID: 20363967
Characterization of the CD48 gene demonstrates a positive element that is specific to Epstein-Barr virus-immortalized B-cell lines and contains an essential NF-kappa B site. PMID: 7815555
NK cells stimulate proliferation of T and NK cells through 2B4/CD48 interactions. PMID: 15210772
Mutation analysis with random DNA identifiers (MARDI) catalogs Pig-a mutations in heterogeneous pools of CD48-deficient T cells derived from DMBA-treated rats. PMID: 26683280
Ox-LDL can enhance the interaction of mice natural killer cells and dendritic cells via the CD48-2B4 pathway. PMID: 21221603
Expression analysis of two SLAM family receptors, SLAMF2 and SLAMF7, in patients with multiple myeloma. PMID: 31115879
2B4, the natural killer and T cell immunoglobulin superfamily surface protein, is a ligand for CD48. PMID: 9841922
Mast cell activation by Mycobacterium tuberculosis: mediator release and role of CD48. PMID: 12759438
Genomic instability on hMSH2, hMLH1, CD48 and IRF4 loci in pulmonary sarcoidosis. PMID: 12521125
CD59 and CD48 expressed by rat retinal pigment epithelial cells are major ligands for the CD2-mediated alternative pathway of T cell activation. PMID: 8621904
sCD48 is elevated in non-allergic but not in allergic persistent rhinitis. PMID: 34477021
Pig embryonic pancreatic tissue as a source for transplantation in diabetes: transient treatment with anti-LFA1, anti-CD48, and FTY720 enables long-term graft maintenance in mice with only mild ongoing immunosuppression. PMID: 19401429
Coexpression of CD58 or CD48 with intercellular adhesion molecule 1 on target cells enhances adhesion of resting NK cells. PMID: 12496412
Rational design of a novel calcium-binding site adjacent to the ligand-binding site on CD2 increases its CD48 affinity. PMID: 18287277
Affinity and kinetic analysis of the interaction of the cell adhesion molecules rat CD2 and CD48. PMID: 7903240
Decrease in cAMP levels promoted by CD48-CD2 interaction correlates with inhibition of apoptosis in B cells. PMID: 8668920
Identification, by protein sequencing and gene transfection, of sgp-60 as the murine homologue of CD48. PMID: 8475091
Prolonged allograft survival by the inhibition of costimulatory CD2 signals but not by modulation of CD48 (CD2 ligand) in the rat. PMID: 8959856
Direct measurements of heterotypic adhesion between the cell surface proteins CD2 and CD48. PMID: 12356317
2B4 inhibits NK-cell fratricide. PMID: 17537992
Alteration of liver immunity by increasing inflammatory response during co-administration of methamphetamine and atazanavir. PMID: 32249638
[Detection of the expression of NK ligands in acute leukemia cell lines by real-time PCR]. PMID: 23597460
Cholesterol-dependent clustering of IL-2Ralpha and its colocalization with HLA and CD48 on T lymphoma cells suggest their functional association with lipid rafts. PMID: 10823948
Murine epidermal Langerhans cells express CD48, which is a counter-receptor for mouse CD2. PMID: 7487136
Activating interactions in human NK cell recognition: the role of 2B4-CD48. PMID: 10359122
Natural-killer cell ligands at the maternal-fetal interface: UL-16 binding proteins, MHC class-I chain related molecules, HLA-F and CD48. PMID: 18658158
Anti-CD2 receptor and anti-CD2 ligand (CD48) antibodies synergize to prolong allograft survival. PMID: 7903681
The chicken SLAM family. PMID: 23064403
Development of an in vivo gene mutation assay using the endogenous Pig-A gene: I. Flow cytometric detection of CD59-negative peripheral red blood cells and CD48-negative spleen T-cells from the rat. PMID: 18626999
Cutting edge: the NK cell receptor 2B4 augments antigen-specific T cell cytotoxicity through CD48 ligation on neighboring T cells. PMID: 12734329
Human mast cell activation by Staphylococcus aureus: interleukin-8 and tumor necrosis factor alpha release and the role of Toll-like receptor 2 and CD48 molecules. PMID: 18644875
The murine Cd48 gene: allelic polymorphism in the IgV-like region. PMID: 9949948
Identification of human endogenous retrovirus transcripts in Hodgkin Lymphoma cells. PMID: 30707417
Dormant and self-renewing hematopoietic stem cells and their niches. PMID: 17442778
Characterization of the Epstein-Barr virus-inducible gene encoding the human leukocyte adhesion and activation antigen BLAST-1 (CD48). PMID: 1847502
Analysis of the structure and interactions of CD2. PMID: 7907562
Transcriptional profiling of Foxo3a and Fancd2 regulated genes in mouse hematopoietic stem cells. PMID: 25984447
Inhibitory 2B4 contributes to NK cell education and immunological derangements in XLP1 patients. PMID: 28386908
Immune Functions of Signaling Lymphocytic Activation Molecule Family Molecules in Multiple Myeloma. PMID: 33451089
CD2 is a dominant target for allogeneic responses. PMID: 12201362
Molecular and Phenotypic Characterization of Escherichia coli Associated with Granulomatous Colitis of Boxer Dogs. PMID: 32854367
Functional study of tilapia T cell activation stimulus signal molecule CD2., PMID:39909121
Fine-tuning spatial-temporal dynamics and surface receptor expression support plasma cell-intrinsic longevity., PMID:38896451
NK and T-lymphocyte Kinetics Predict Outcome in Myeloma Patients Treated With Elotuzumab, Lenalidomide Plus Dexamethasone., PMID:38434915
Epigenetic regulation of CD38/CD48 by KDM6A mediates NK cell response in multiple myeloma., PMID:38355622
Gene signatures to therapeutics: Assessing the potential of ivermectin against t(4;14) multiple myeloma., PMID:38292661
The Immunogenicity of CpG, MF59-like, and Alum Adjuvant Delta Strain Inactivated SARS-CoV-2 Vaccines in Mice., PMID:38250873
Seven chromatin regulators as immune cell infiltration characteristics, potential diagnostic biomarkers and drugs prediction in hepatocellular carcinoma., PMID:37903974
FCM marker importance for MRD assessment in T-cell acute lymphoblastic leukemia: An AIEOP-BFM-ALL-FLOW study group report., PMID:37776305
Impact of HIV-1 Vpu-mediated downregulation of CD48 on NK-cell-mediated antibody-dependent cellular cytotoxicity., PMID:37404017
Fine-tuning spatial-temporal dynamics and surface receptor expression support plasma cell-intrinsic longevity., PMID:36891288
Programmed Cell Death-1 (PD-1) anchoring to the GPI-linked co-receptor CD48 reveals a novel mechanism to modulate PD-1-dependent inhibition of human T cells., PMID:36889184
Oral mucosal breaks trigger anti-citrullinated bacterial and human protein antibody responses in rheumatoid arthritis., PMID:36812347
Unraveling the surface proteomic profile of multiple myeloma to reveal new immunotherapeutic targets and markers of drug resistance., PMID:36311892
Elevated levels of sCD48 are inversely correlated with markers of disease activity in bullous pemphigoid., PMID:36134505
Cromolyn Sodium differentially regulates human mast cell and mouse leukocyte responses to control allergic inflammation., PMID:35278626
CD48-expressing non-small-cell lung cancer cells are susceptible to natural killer cell-mediated cytotoxicity., PMID:34905179
GDF15 induces immunosuppression via CD48 on regulatory T cells in hepatocellular carcinoma., PMID:34489334
Elevated Serum Level of CD48 in Patients with Intermittent Allergic Rhinitis., PMID:32966985
Salivary gland epithelial cells from patients with Sjögren's syndrome induce B-lymphocyte survival and activation., PMID:32843324
The Use of Antibody Arrays in the Discovery of New Plasma Biomarkers for Endometriosis., PMID:32016799
Myeloma: next generation immunotherapy., PMID:31808859
An update on potentials and promises of T cell co-signaling molecules in transplantation., PMID:31696513
TCR repertoire and CDR3 motif analyses depict the role of αβ T cells in Ankylosing spondylitis., PMID:31477563
First-in-human phase 1 study of IT1208, a defucosylated humanized anti-CD4 depleting antibody, in patients with advanced solid tumors., PMID:31340866
Expression analysis of two SLAM family receptors, SLAMF2 and SLAMF7, in patients with multiple myeloma., PMID:31115879
[Evaluation of therapeutic sensitivity of retinal ganglion cells to targeted peptide bioregulator in culture]., PMID:30830079
Evaluation of Soluble CD48 Levels in Patients with Allergic and Nonallergic Asthma in Relation to Markers of Type 2 and Non-Type 2 Immunity: An Observational Study., PMID:30306094
[FAMILIAL OCCURRENCE OF SUMMER-TYPE HYPERSENSITIVITY PNEUMONITIS IN DEFECTIVE HOME]., PMID:30146627
Analysis of mutation in the rat Pig-a assay: II. Studies with bone marrow granulocytes., PMID:30091248
No difference in human mast cells derived from peanut allergic versus non-allergic subjects., PMID:29992767
[A CASE OF SUMMER-TYPE HYPERSENSITIVITY PNEUMONITIS ACCOMPANIED BY THE SYNDROME OF INAPPROPRIATE SECRETION OF ANTIDIURETIC HORMONE]., PMID:29459527
Non-IgE mediated mast cell activation., PMID:29431205
Impact of chronic blood viral infection on lymphocyte telomere length in Chornobyl clean-up workers in a remote period after radiation exposure., PMID:29286521
A cellular platform for the evaluation of immune checkpoint molecules., PMID:29029399
Fab antibody fragment-functionalized liposomes for specific targeting of antigen-positive cells., PMID:28939491
Expansion of cytotoxic natural killer cells using irradiated autologous peripheral blood mononuclear cells and anti-CD16 antibody., PMID:28894091
In Vivo Rat T-Lymphocyte Pig-a Assay: Detection and Expansion of Cells Deficient in the GPI-Anchored CD48 Surface Marker for Analysis of Mutation in the Endogenous Pig-a Gene., PMID:28748462
2B4-SAP signaling is required for the priming of naive CD8+ T cells by antigen-expressing B cells and B lymphoma cells., PMID:28344876
Crystal Structure of the Extracellular Domain of the Human Dendritic Cell Surface Marker CD83., PMID:28315353
Grouper (Epinephelus coioides) TCR signaling pathway was involved in response against Cryptocaryon irritans infection., PMID:28286257
Constitutive Kit activity triggers B-cell acute lymphoblastic leukemia-like disease in mice., PMID:27664314
Anti-CD48 Monoclonal Antibody Attenuates Experimental Autoimmune Encephalomyelitis by Limiting the Number of Pathogenic CD4+ T Cells., PMID:27581174
Human Diversity in a Cell Surface Receptor that Inhibits Autophagy., PMID:27345162
Fine-tuning of CD8(+) T-cell effector functions by targeting the 2B4-CD48 interaction., PMID:26860368
Selective Loss of Signaling Lymphocytic Activation Molecule Family Member 4-Positive CD8+ T Cells Contributes to the Decreased Cytotoxic Cell Activity in Systemic Lupus Erythematosus., PMID:26314831
Multiple myeloma: New surface antigens for the characterization of plasma cells in the era of novel agents., PMID:26287276
[Immune defects in multiple myeloma]., PMID:25626304
Combined immune checkpoint protein blockade and low dose whole body irradiation as immunotherapy for myeloma., PMID:25614821
[Expression of CD48 as a live marker to distinguish division of hematopoietic stem cells]., PMID:24989257
Successful treatment for West syndrome with severe combined immunodeficiency., PMID:24534054
For research use only. Not for human or drug use.
