Catalog No.
YHF40701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Arg394
Predicted molecular weight
46.92 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P61160
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Actin-like protein 2, ARP2, Actin-related protein 2, ACTR2
Note
For research use only.
Myosin-I synergizes with Arp2/3 complex to enhance the pushing forces of branched actin networks., PMID:39270022
Lamellipodia-Mediated Osteoblast Haptotaxis Guided by Fibronectin Ligand Concentrations on a Multiplex Chip., PMID:39286887
Arpin deficiency increases actomyosin contractility and vascular permeability., PMID:39298260
The Rac1-PAK1-Arp2/3 signaling axis regulates CHIKV nsP1-induced filopodia and optimal viral genome replication., PMID:39297643
Arp2/3 complex activity enables nuclear YAP for naïve pluripotency of human embryonic stem cells., PMID:39319536
Scar/WAVE drives actin protrusions independently of its VCA domain using proline-rich domains., PMID:39332399
Aspartyl proteases target host actin nucleator complex protein to limit epithelial innate immunity., PMID:39349750
Actin-related protein 2/3 complex subunit 1B promotes ovarian cancer progression by regulating the AKT/PI3K/mTOR signaling pathway., PMID:39360160
Identification and RT-qPCR Validation of Biomarkers Based on Butyrate Metabolism-Related Genes to Predict Recurrent Miscarriage., PMID:39372587
Actin-driven nanotopography promotes stable integrin adhesion formation in developing tissue., PMID:39375335
Rapid identification of primary atopic disorders (PAD) by a clinical landmark-guided, upfront use of genomic sequencing., PMID:39381601
Endosomal actin branching, fission, and receptor recycling require FCHSD2 recruitment by MICAL-L1., PMID:39382837
Should it stay or should it go: gap junction protein GJA1/Cx43 conveys damaged lysosomes to the cell periphery to potentiate exocytosis., PMID:39394955
Reconstitution of Arp2/3-nucleated actin assembly with proteins CP, V-1, and CARMIL., PMID:39437783
Spatiotemporal analysis of F-actin polymerization with micropillar arrays reveals synchronization between adhesion sites., PMID:39441710
CYRI controls epidermal wound closure and cohesion of invasive border cell cluster in Drosophila., PMID:39453414
Neutrophils exhibit flexible migration strategies and trail formation mechanisms on varying adhesive substrates., PMID:39454506
ARP2/3 complex affects myofibroblast differentiation and migration in pancreatic ductal adenocarcinoma., PMID:39472297
Spatiotemporal coordination of actin regulators generates invasive protrusions in cell-cell fusion., PMID:39487253
Viscosity regulates cell spreading and cell-extracellular matrix interactions., PMID:39529371
Plasma proteomic signature of chronic psychosocial stress in mice., PMID:39532277
Vinculin-Arp2/3 interaction inhibits branched actin assembly to control migration and proliferation., PMID:39547716
HIV-1 budding requires cortical actin disassembly by the oxidoreductase MICAL1., PMID:39556735
Recurrent eosinophilia with a novel homozygous ARPC1B mutation., PMID:39609360
Actin-based deformations of the nucleus control mouse multiciliated ependymal cell differentiation., PMID:39662468
From Molecules to Amoeboid Movement: A New Way for Understanding the Morphology Through Actin-Binding Proteins., PMID:39766290
Mitochondria- and ER-associated actin are required for mitochondrial fusion., PMID:39774009
High expression of ARPC1B promotes the proliferation and apoptosis of clear cell renal cell carcinoma cells, leading to a poor prognosis., PMID:39818256
Dietary limonin alleviates Salmonella Typhimurium-induced colitis via dual targeting virulence SopB and SopE2 and inhibiting RAC1/CDC42/Arp2/3 pathway and regulating gut microbiota., PMID:39820212
Two ligands of Arp2/3 complex, yeast coronin and GMF, interact and synergize in pruning branched actin networks., PMID:39826693
Targeting ARPC1B Overcomes Immune Checkpoint Inhibitor Resistance in Glioblastoma by Reversing Protumorigenic Macrophage Polarization., PMID:39841088
Pan-cancer analysis of Arp2/3 complex subunits: focusing on ARPC1A's role and validating the ARPC1A/c-Myc axis in non-small cell lung cancer., PMID:39867911
Proteogenomic analysis reveals Arp 2/3 complex as a common molecular mechanism in high risk pancreatic cysts and pancreatic cancer., PMID:39890846
Molecular mechanisms of hotspot variants in cytoskeletal β-actin associated with Baraitser-Winter syndrome., PMID:39930656
The WASP/WAVE Protein Family in Breast Cancer and Their Role in the Metastatic Cascade., PMID:39993807
Changes in Protein Expression in Warmed Human Lens Epithelium Cells Using Shotgun Proteomics., PMID:40005403
NPF binding to Arp2 is allosterically linked to the release of ArpC5's N-terminal tail and conformational changes in Arp2/3 complex., PMID:40042350
Cell signaling facilitates apical constriction by basolaterally recruiting Arp2/3 via Rac and WAVE., PMID:40042443
Molecular mechanism of Arp2/3 complex activation by nucleation-promoting factors and an actin monomer., PMID:40048273
YAP/TAZ-mediated nuclear membrane rupture in promoting senescence of skeletal muscle associated with COPD., PMID:40075503
Membrane composition and curvature in SNX9-mediated actin polymerization., PMID:40105919
Gαi2 Induces Cell Migration in PC3 Prostate Cancer Cells in the Absence of Rac1 Activation., PMID:40141305
Dynamic Plasma Membrane Topography Linked With Arp2/3 Actin Network Induction During Cell Shape Change., PMID:40159841
[Aurora-A overexpression promotes cervical cancer cell invasion and metastasis by activating the NF-κBp65/ARPC4 signaling axis]., PMID:40294934
Targeted Regulation of HSP70 by the ARP2/3 Complex in Mammary Epithelial Cells and Its Impact on Host Cell Apoptosis., PMID:40305275
Liangxue Qushi Zhiyang Decoction Inhibits Atopic Dermatitis in Mice via FcγR-Mediated Phagocytosis., PMID:40322063
Single-cell proteomics analysis of human oocytes during GV-to-MI transition., PMID:40359387
SECS, drugs, and Rac1&Rho: regulation of EnNaC in vascular endothelial cells., PMID:40402207
JMY powers dendritogenesis and is regulated by CaM revealing a general, critical principle in neuromorphogenesis., PMID:40404909
ARP2/3 regulates cell surface dynamics of CeTOCA-1 in C. elegans zygotes., PMID:40501091
For research use only. Not for human or drug use.
