Anti-POU2F2 Polyclonal Antibody

Catalog No.

PHC38401

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human POU2F2 (Phe236-Thr398).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Oct-2,POU domain,class 2,transcription factor 2,OTF-2,OCT2,Octamer-binding protein 2,POU2F2,Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2,Octamer-binding transcription factor 2,OTF2

Purification

Purified by antigen affinity column.

Accession

P09086

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Increased expression of interleukin-21-inducible genes in minor salivary glands are associated with primary Sjögren's syndrome disease characteristics., PMID:33247940

Regulation of normal B-cell differentiation and malignant B-cell survival by OCT2., PMID:26993806

MiR-210 is induced by Oct-2, regulates B cells, and inhibits autoantibody production., PMID:23960236

B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1., PMID:23045607

CD86 stimulation on a B cell activates the phosphatidylinositol 3-kinase/Akt and phospholipase C gamma 2/protein kinase C alpha beta signaling pathways., PMID:16709832

Alterations of loci encoding PU.1, BOB1, and OCT2 transcription regulators do not correlate with their suppressed expression in Hodgkin lymphoma., PMID:15796964

Analysis of transcription factor OCT.1, OCT.2 and BOB.1 expression using tissue arrays in classical Hodgkin's lymphoma., PMID:15257313

The HoxC4 homeodomain protein mediates activation of the immunoglobulin heavy chain 3' hs1,2 enhancer in human B cells. Relevance to class switch DNA recombination., PMID:15252056

CD86 and beta2-adrenergic receptor signaling pathways, respectively, increase Oct-2 and OCA-B Expression and binding to the 3'-IgH enhancer in B cells., PMID:15024018

All known in vivo functions of the Oct-2 transcription factor require the C-terminal protein domain., PMID:14978099

NF-kappa B and Oct-2 synergize to activate the human 3' Igh hs4 enhancer in B cells., PMID:14707079

Critical role for the Oct-2/OCA-B partnership in Ig-secreting cells., PMID:14662861

The B-cell transcription factors BSAP, Oct-2, and BOB.1 and the pan-B-cell markers CD20, CD22, and CD79a are useful in the differential diagnosis of classic Hodgkin lymphoma., PMID:14608905

Disruption of the B-cell specific transcriptional program in HHV-8 associated primary effusion lymphoma cell lines., PMID:12592383

Primary mediastinal B-cell lymphoma: high frequency of BCL-6 mutations and consistent expression of the transcription factors OCT-2, BOB.1, and PU.1 in the absence of immunoglobulins., PMID:12507907

Differential regulation of CD36 expression in antigen-presenting cells: Oct-2 dependence in B lymphocytes but not dendritic cells or macrophages., PMID:12356675

Loss of PU.1 expression is associated with defective immunoglobulin transcription in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease., PMID:11929801

A conserved sequence block in the murine and human T cell receptor Jalpha loci interacts with developmentally regulated nucleoprotein complexes in vitro and associates with GATA-3 and octamer-binding factors in vivo., PMID:11385613

B cell development and immunoglobulin gene transcription in the absence of Oct-2 and OBF-1., PMID:11135581

Down-regulation of BOB.1/OBF.1 and Oct2 in classical Hodgkin disease but not in lymphocyte predominant Hodgkin disease correlates with immunoglobulin transcription., PMID:11154228

Transcriptional regulation of the human osteopontin promoter: functional analysis and DNA-protein interactions., PMID:11126367

An essential octamer motif in the mb-1 (Igalpha) promoter., PMID:11000405

An upstream Oct-1- and Oct-2-binding silencer governs B29 (Ig beta) gene expression., PMID:10679093

Binding of octamer factors to a novel 3'-positive regulatory element in the mouse interleukin-5 gene., PMID:10660628

Interaction and functional interference of C/EBPbeta with octamer factors in immunoglobulin gene transcription., PMID:10602039

Transcriptional regulation of the murine 3' IgH enhancer by OCT-2., PMID:10591177

The activity of the human interleukin-5 conserved lymphokine element 0 is regulated by octamer factors in human cells., PMID:10491186

Transcription factor effects on chromosome constitution of cell hybrids., PMID:9925930

oct-2 gene disruption eliminates the peritoneal B-1 lymphocyte lineage and attenuates B-2 cell maturation and function., PMID:9548466

Using altered specificity Oct-1 and Oct-2 mutants to analyze the regulation of immunoglobulin gene transcription., PMID:9384588

Temporal control of IgH gene expression in developing B cells by the 3' locus control region., PMID:9442395

Diverse transcription factors are involved in the quantitative regulation of transcriptional activation of kappa promoters., PMID:9209478

Characterization of constitutive and inducible transcription factors binding to the P2 NF-AT site in the human interleukin-4 promoter., PMID:9133600

Decreased production of IL-2 and IFN-gamma by stimulated splenocytes from mice bearing plasma cell tumors is associated with alteration of DNA-binding factors., PMID:8982782

Octamer independent activation of transcription from the kappa immunoglobulin germline promoter., PMID:8972869

High-level nuclear NF-kappa B and Oct-2 is a common feature of cultured Hodgkin/Reed-Sternberg cells., PMID:8639794

Concerted repression of an immunoglobulin heavy-chain enhancer, 3' alpha E(hs1,2)., PMID:8633077

Induction of the Oct-2 transcription factor in primary sensory neurons during inflammation is nerve growth factor-dependent., PMID:8929970

Real-time analysis of Oct protein-octamer interaction and transcription complex assembly., PMID:8643112

Role of Oct-2 in immunoglobulin gene silencing., PMID:7486513

Interaction of Oct-1 with TFIIB. Implications for a novel response elicited through the proximal octamer site of the lipoprotein lipase promoter., PMID:7642649

Stimulation of basal transcription from the mouse mammary tumor virus promoter by Oct proteins., PMID:7609037

Diphosphoryl lipid A from Rhodobacter sphaeroides transiently activates NF-kappa B but inhibits lipopolysaccharide induction of kappa light chain and Oct-2 in the B-cell lymphoma line 70Z/3., PMID:7868225

A B-cell coactivator of octamer-binding transcription factors., PMID:7779176

Involvement of the Ets family factor PU.1 in the activation of immunoglobulin promoters., PMID:7822329

Oct-2 is required early in T cell-independent B cell activation for G1 progression and for proliferation., PMID:7600291

Constitutively expressed Oct-2 prevents immunoglobulin gene silencing in myeloma x T cell hybrids., PMID:7600290

Simultaneous activation of Ig and Oct-2 synthesis and reduction of surface MHC class II expression by IL-6., PMID:7930570

Two different IFN-gamma nonresponsive variants derived from the B-cell lymphoma 70Z/3., PMID:8039828

Genetic analysis of transcription factors implicated in B lymphocyte development., PMID:7616055

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