Catalog No.
PHC38201
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human FGF2 (Pro143-Ser288).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
bFGF,FGF2,Basic fibroblast growth factor,HBGF-2,FGFB,FGF-2,Heparin-binding growth factor 2,Fibroblast growth factor 2
Purification
Purified by antigen affinity column.
Accession
P09038
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Simultaneous inhibition of fibroblast growth factor-2 and vascular endothelial growth factor-a with RC28-E in diabetic macular edema: a phase 2 randomised trial., PMID:40122579
A narrative review of basic and clinical studies for vocal fold regeneration therapies., PMID:39476786
Chemoenzymatic Synthesis of DNP-Functionalized FGFR1-Binding Peptides as Novel Peptidomimetic Immunotherapeutics for Treating Lung Cancer., PMID:39145988
External validation of serum biomarkers predicting short-term and mid/long-term relapse in patients with Crohn's disease stopping infliximab., PMID:39134391
LNMAC Promotes Cervical Squamous Cell Carcinoma Lymphatic Metastasis via Epigenetic Regulation of FGF2-Induced Lymphangiogenesis., PMID:39119899
Basic Fibroblast Growth Factor Accumulation in Culture Medium Masks the Direct Antitumor Effect of Anti-VEGF Agent Bevacizumab., PMID:39002014
Fluorescence-activated nuclear sorting (FANS) of nuclei from in vitro-generated syncytiotrophoblast., PMID:38944560
Equine Endothelial Cells Show Pro-Angiogenic Behaviours in Response to Fibroblast Growth Factor 2 but Not Vascular Endothelial Growth Factor A., PMID:38892205
Cytokine, Anti-SARS-CoV-2 Antibody, and Neutralizing Antibody Levels in Conventional Blood Donors Who Have Recovered from COVID-19., PMID:38867805
Targeting ONECUT2 inhibits tumor angiogenesis via down-regulating ZKSCAN3/VEGFA., PMID:38797268
Status of alternative angiogenic pathways in glioblastoma resected under and after bevacizumab treatment., PMID:38619734
Promising horizons in achondroplasia along with the development of new drugs., PMID:38569854
The "Brain Milking" Method for the Isolation of Neural Stem Cells and Oligodendrocyte Progenitor Cells from Live Rats., PMID:38407295
Identification and validation of basic fibroblast growth factor as a prognostic biomarker for the response of lung adenocarcinoma patients to bevacizumab treatment., PMID:38043261
Clinical proof of concept for anti-FGF2 therapy in exudative age-related macular degeneration (nAMD): phase 2 trials in treatment-naïve and anti-VEGF pretreated patients., PMID:38036609
Autophagy activates EGR1 via MAPK/ERK to induce FGF2 in renal tubular cells for fibroblast activation and fibrosis during maladaptive kidney repair., PMID:37978868
Tumor-derived GABA promotes lung cancer progression by influencing TAMs polarization and neovascularization., PMID:37977069
Analysis of proteins released from osteoarthritic cartilage by compressive loading., PMID:37880329
Shedding New Light: Novel Therapies for Achondroplasia and Growth Disorders., PMID:37704353
Impaired proliferation and migration of HUVEC and melanoma cells by human anti-FGF2 mAbs derived from a murine hybridoma by guided selection., PMID:37661761
Humanized disulfide-stabilized diabody against fibroblast growth factor-2 inhibits PD-L1 expression and epithelial-mesenchymal transition in hepatoma cells through STAT3., PMID:37489553
Fibroblasts are the most suitable cell source for regenerative medicine due to their high intracellular fibroblast growth factor 2 content., PMID:37457362
Small Extracellular Vesicle-Derived vWF Induces a Positive Feedback Loop between Tumor and Endothelial Cells to Promote Angiogenesis and Metastasis in Hepatocellular Carcinoma., PMID:37387563
Expression and Purification of FGFR1-Fc Fusion Protein and Its Effects on Human Lung Squamous Carcinoma., PMID:37160564
Endothelial Progenitor Cells Promote Osteosarcoma Progression and Invasiveness via AKT/PI3K Signaling., PMID:36980704
Tumor Cell-Autonomous SHP2 Contributes to Immune Suppression in Metastatic Breast Cancer., PMID:36969745
Fibroblast Growth Factor 2 Is Produced By Renal Tubular Cells to Act as a Paracrine Factor in Maladaptive Kidney Repair After Cisplatin Nephrotoxicity., PMID:36925200
Knockdown of Programmed Death 1 Inhibited Progression of Papillary Thyroid Carcinoma in Mice., PMID:36876839
Fibroblast Growth Factor-2 and the Invasive Potential in Urothelial Malignancies of the Bladder., PMID:36843751
Paradoxical cancer cell stimulation by IFNγ drives tumor hyperprogression upon checkpoint blockade immunotherapy., PMID:36787694
Basic Fibroblast Growth Factor Blockade Leads to Distinct Cellular Responses in Melanoma B16 Cells., PMID:36787008
Distinct systemic immune networks define severe vs. mild COVID-19 in hematologic and solid cancer patients., PMID:36700209
A novel agonist with homobivalent single-domain antibodies that bind the FGF receptor 1 domain III functions as an FGF2 ligand., PMID:36529290
A comparative mRNA- and miRNA transcriptomics reveals novel molecular signatures associated with metastatic prostate cancers., PMID:36468011
Application of an antibody microarray for serum protein profiling of coronary artery stenosis., PMID:36166954
Targeting FAPα-expressing hepatic stellate cells overcomes resistance to antiangiogenics in colorectal cancer liver metastasis models., PMID:35951441
Identification and characterization of FGFR2+ hematopoietic stem cell-derived fibrocytes as precursors of cancer-associated fibroblasts induced by esophageal squamous cell carcinoma., PMID:35941662
Dry preserved multilayered fibroblast cell sheets are a new manageable tool for regenerative medicine to promote wound healing., PMID:35869108
Diverse actions of sirtuin-1 on ovulatory genes and cell death pathways in human granulosa cells., PMID:35840944
1,25OH-Vitamin D3 and IL-17 Inhibition Modulate Pro-Fibrotic Cytokines Production in Peripheral Blood Mononuclear Cells of Patients with Systemic Sclerosis., PMID:35693738
A monoclonal antibody against basic fibroblast growth factor attenuates cisplatin resistance in lung cancer by suppressing the epithelial-mesenchymal transition., PMID:35649742
Acceptance of Murine Islet Allografts Without Immunosuppression in Inguinal Subcutaneous White Adipose Tissue Pretreated With bFGF., PMID:35604856
Tubular cells produce FGF2 via autophagy after acute kidney injury leading to fibroblast activation and renal fibrosis., PMID:35491858
Nuclear Localization of Fibroblast Growth Factor Receptor 1 in Breast Cancer Cells Interacting with Cancer Associated Fibroblasts., PMID:35419302
Measurement of anti-suprabasin antibodies, multiple cytokines and chemokines as potential predictive biomarkers for neuropsychiatric systemic lupus erythematosus., PMID:35296428
Human Growth Factor/Immunoglobulin Complexes for Treatment of Myocardial Ischemia-Reperfusion Injury., PMID:35295649
Anti-CXCL10 monoclonal antibody therapy protects against the diabetic retinopathy in the mouse model induced by streptozotocin., PMID:35276554
Novel SH-SAW Biosensors for Ultra-Fast Recognition of Growth Factors., PMID:35049645
Regulation of Transplanted Cell Homing by FGF1 and PDGFB after Doxorubicin Myocardial Injury., PMID:34831221
A Cardiac Mitochondrial FGFR1 Mediates the Antithetical Effects of FGF2 Isoforms on Permeability Transition., PMID:34685716
For research use only. Not for human or drug use.
