Catalog No.
YHD59601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr97-Gln173
Predicted molecular weight
21.03 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P23588
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
EIF4B, Eukaryotic translation initiation factor 4B, eIF-4B
Note
For research use only.
Organotin and organochlorine toxicants activate key translational regulatory proteins in human immune cells., PMID:36372856
Upregulation of ATF4-LAMP3 Axis by ORF45 Facilitates Lytic Replication of Kaposi's Sarcoma-Associated Herpesvirus., PMID:36377873
13-Acetoxysarcocrassolide induces apoptosis in human hepatocellular carcinoma cells through mitochondrial dysfunction and suppression of the PI3K/AKT/mTOR/p70S6K signalling pathway., PMID:36416062
Patient-specific identification of genome-wide DNA-methylation differences between intracranial and extracranial melanoma metastases., PMID:36624125
The transcript interactome of skeletal muscle RNA binding protein motif 3 (RBM3)., PMID:36750123
CDK13 phosphorylates the translation machinery and promotes tumorigenic protein synthesis., PMID:36882522
A novel circular RNA circRBMS3 regulates proliferation and metastasis of osteosarcoma by targeting miR-424-eIF4B/YRDC axis., PMID:36897170
Rumen-Protected Lysine and Methionine Supplementation Reduced Protein Requirement of Holstein Bulls by Altering Nitrogen Metabolism in Liver., PMID:36899700
Expression of Eukaryotic Translation Initiation Factors in the Urothelial Carcinoma of the Bladder., PMID:36974813
Lactoferrin attenuates cardiac fibrosis and cardiac remodeling after myocardial infarction via inhibiting mTORC1/S6K signaling pathway., PMID:37351157
Backbone resonance assignments of the C-terminal region of human translation initiation factor eIF4B., PMID:37368134
Curcumin analog GO-Y030 inhibits tumor metastasis and glycolysis., PMID:37656908
SP1-Induced Upregulation of LncRNA AFAP1-AS1 Promotes Tumor Progression in Triple-Negative Breast Cancer by Regulating mTOR Pathway., PMID:37686205
Exosomal miR-30a-5p promoted intrahepatic cholangiocarcinoma progression by increasing angiogenesis and vascular permeability in PDCD10 dependent manner., PMID:37781039
Influence of FTDP-17 mutants on circular Tau RNAs., PMID:37786725
Complex CDKL5 translational regulation and its potential role in CDKL5 deficiency disorder., PMID:37964795
Decoding the Heterogeneity and Specialized Function of Translation Machinery Through Ribosome Profiling in Yeast Mutants of Initiation Factors., PMID:37997253
RNA helicase EIF4A1-mediated translation is essential for the GC response., PMID:38011999
PABP-driven secondary condensed phase within RSV inclusion bodies activates viral mRNAs for ribosomal recruitment., PMID:38072230
Exploring biomarkers in trigeminal neuralgia patients operated with microvascular decompression: A comparison with multiple sclerosis patients and non-neurological controls., PMID:38158702
The Anticancer Effects of Marine Carotenoid Fucoxanthin through Phosphatidylinositol 3-Kinase (PI3K)-AKT Signaling on Triple-Negative Breast Cancer Cells., PMID:38202644
Identification and characterization of TOR in Macrobrachium rosenbergii and its role in muscle protein and lipid production., PMID:38267514
Influence of FTDP-17 mutants on circular tau RNAs., PMID:38286213
Methionyl-Methionine Dipeptide Enhances Mammogenesis and Lactogenesis by Suppressing the Expression of a Novel Long Noncoding RNA MGPNCR to Inhibit eIF4B Dephosphorylation., PMID:38501560
Identification of Eukaryotic Translation Initiation Factor 4B as a Novel Candidate Gene for Congenital Hypothyroidism., PMID:38654471
Poly(A)-binding protein promotes VPg-dependent translation of potyvirus through enhanced binding of phosphorylated eIFiso4F and eIFiso4F∙eIF4B., PMID:38696388
Single-cell transcriptome revealed dysregulated RNA-binding protein expression patterns and functions in human ankylosing spondylitis., PMID:38770048
Functional transcriptome analysis revealed major changes in pathways affecting systems biology of Tharparkar cattle under seasonal heat stress., PMID:38855148
Genetic evidence supporting potential causal roles of EIF4 family in breast cancer: a two-sample randomized Mendelian study., PMID:39215053
Eukaryotic initiation factor 4B is a multi-functional RNA binding protein that regulates histone mRNAs., PMID:39225047
Disordered regions of human eIF4B orchestrate a dynamic self-association landscape., PMID:39384813
Leucine-Rich Alpha-2-Glycoprotein 1 Promotes Metastatic Colorectal Cancer Growth Through Human Epidermal Growth Factor Receptor 3 Signaling., PMID:39393543
In-depth proteomics and Phosphoproteomics reveal biomarkers and molecular pathways of chronic intermittent hypoxia in mice., PMID:39433155
Comparative Proteomic and Phosphoproteomic Analyses Reveal Molecular Signatures of Myocardial Infarction and Transverse Aortic Constriction in Aged Mouse Models., PMID:39502510
Probing the Mesenchymal Stem Cell Aging through In silico Assessment of Extracellular Vesicle-mediated miRNAs., PMID:39670493
Trypanosomatid DRBD9s are likely to be eIF4B orthologues., PMID:39703104
40S ribosomal subunits scan mRNA for the start codon by one-dimensional diffusion., PMID:39803544
Yeast Eukaryotic Initiation Factor 4B Remodels the MRNA Entry Site on the Small Ribosomal Subunit., PMID:39847343
YTHDF3 drives tumor growth and metastasis by recruiting eIF4B to promote Notch2 translation in breast cancer., PMID:39924078
Intestinal Gastrin/CCKBR Axis Protects against Type 2 Diabetes by Reducing Intestinal Glucose Absorption through the PI3K/Akt/eIF4B Signaling Pathway., PMID:39950948
Proteome-wide Mendelian randomization identifies causal plasma proteins in prostate cancer development., PMID:39994764
Interaction of dietary replacements of fishmeal by protein blend and feeding frequency on growth performance and protein utilization of gibel carp (Carassius gibelio var. CAS V)., PMID:39995523
Eukaryotic initiation factors eIF4F and eIF4B promote translation termination upon closed-loop formation., PMID:40066881
The proximity proteome of pre-40S pre-ribosomal particle components PNO1 and NOB1 using turboID proximity labeling technology., PMID:40157618
Transcriptome remodeling and adaptive preservation of muscle protein content in hibernating black bears., PMID:40166218
Lysine-specific demethylase 1 controls key OSCC preneoplasia inducer STAT3 through CDK7 phosphorylation during oncogenic progression and immunosuppression., PMID:40246812
A structural element within the 5'UTR of β-catenin mRNA modulates its translation under hypoxia., PMID:40309781
Genetic Evidence Supporting a Causal Association Between mTORC1-Dependent Circulating Protein Levels and Diabetic Retinopathy., PMID:40314641
The Functional Impact of the Noncoding SNP rs3741442 on Orofacial Clefting., PMID:40353495
HMGA2 and protein leucine methylation drive pancreatic cancer lineage plasticity., PMID:40419509
For research use only. Not for human or drug use.
