Catalog No.
YHE67101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr237-Gly291
Predicted molecular weight
19.12 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P49639
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HOX1F, HOXA1, Homeobox protein Hox-1F, Homeobox protein Hox-A1
Note
For research use only.
Long Non-Coding RNA HOXA Transcript Antisense RNA Myeloid-Specific 1-HOXA1 Axis Downregulates the Immunosuppressive Activity of Myeloid-Derived Suppressor Cells in Lung Cancer., PMID:29662483
MicroRNA‑577 inhibits the migration and invasion of hepatocellular carcinoma cells by targeting homeobox A1., PMID:29693150
Long noncoding RNA HOTTIP cooperates with CCCTC-binding factor to coordinate HOXA gene expression., PMID:29698677
Long Non-Coding RNA MEG3 Functions as a Competing Endogenous RNA to Regulate HOXA11 Expression by Sponging miR-181a in Multiple Myeloma., PMID:30134227
Over-expressed lncRNA HOTAIRM1 promotes tumor growth and invasion through up-regulating HOXA1 and sequestering G9a/EZH2/Dnmts away from the HOXA1 gene in glioblastoma multiforme., PMID:30376874
iDEP: an integrated web application for differential expression and pathway analysis of RNA-Seq data., PMID:30567491
microRNA‑577 inhibits cell proliferation and invasion in non‑small cell lung cancer by directly targeting homeobox A1., PMID:30628697
Cancer Stem Cell based molecular predictors of tumor recurrence in Oral squamous cell carcinoma., PMID:30641296
Ethanol promotes differentiation of embryonic stem cells through retinoic acid receptor-γ., PMID:30737277
circEIF4G2 modulates the malignant features of cervical cancer via the miR‑218/HOXA1 pathway., PMID:30896864
Long non-coding RNA 00152 promotes cell proliferation in cervical cancer via regulating miR-216b-5p/HOXA1 axis., PMID:31114990
Elevated microRNA-145 inhibits the development of oral squamous cell carcinoma through inactivating ERK/MAPK signaling pathway by down-regulating HOXA1., PMID:31138758
A distal enhancer maintaining Hoxa1 expression orchestrates retinoic acid-induced early ESCs differentiation., PMID:31147716
MiR-99a suppressed cell proliferation and invasion by directly targeting HOXA1 through regulation of the AKT/mTOR signaling pathway and EMT in ovarian cancer., PMID:31210292
MicroRNA-99a-5p alleviates atherosclerosis via regulating Homeobox A1., PMID:31325426
Glutamylation of deubiquitinase BAP1 controls self-renewal of hematopoietic stem cells and hematopoiesis., PMID:31699823
[Effects of HOXA1 Gene Antisense Oligonucleotides on Growth of Esophageal Cancer Cells]., PMID:31950785
miR-18a-3p Encourages Apoptosis of Chondrocyte in Osteoarthritis via HOXA1 Pathway., PMID:32013856
microRNA-100 functions as a tumor suppressor in non-small cell lung cancer via regulating epithelial-mesenchymal transition and Wnt/β-catenin by targeting HOXA1., PMID:32364673
Long non-coding RNA SNHG1 activates HOXA1 expression via sponging miR-193a-5p in breast cancer progression., PMID:32497022
Bosley-Salih-Alorainy syndrome in patients from India., PMID:32864817
Long noncoding RNA HOTAIRM1 promotes myeloid-derived suppressor cell expansion and suppressive functions through up-regulating HOXA1 expression during latent HIV infection., PMID:33048872
LncRNA HOTAIRM1 promotes MDSC expansion and suppressive functions through the HOXA1-miR124 axis during HCV infection., PMID:33328510
MiR-10a-5p restrains the aggressive phenotypes of ovarian cancer cells by inhibiting HOXA1., PMID:33332731
CircWHSC1 serves as an oncogene to promote hepatocellular carcinoma progression., PMID:33410156
Promotive role of microRNA‑150 in hippocampal neurons apoptosis in vascular dementia model rats., PMID:33576461
Long non‑coding RNA AFAP1‑AS1 facilitates the growth and invasiveness of oral squamous cell carcinoma by regulating the miR‑145/HOXA1 axis., PMID:33650645
MiR-30b-5p Influences Chronic Exercise Arthritic Injury by Targeting Hoxa1., PMID:33930933
IGF1-mediated HOXA13 overexpression promotes colorectal cancer metastasis through upregulating ACLY and IGF1R., PMID:34075028
CircRASSF2 acts as a prognostic factor and promotes breast cancer progression by modulating miR-1205/HOXA1 axis., PMID:34180753
Downregulation of LINC00665 suppresses the progression of lung adenocarcinoma via regulating miR-181c-5p/ZIC2 axis., PMID:34232917
Silencing long non-coding RNA DLX6-AS1 or restoring microRNA-193b-3p enhances thyroid carcinoma cell autophagy and apoptosis via depressing HOXA1., PMID:34514705
Enhancer architecture-dependent multilayered transcriptional regulation orchestrates RA signaling-induced early lineage differentiation of ESCs., PMID:34723340
Elevated lncRNA-UCA1 upregulates EZH2 to promote inflammatory response in sepsis-induced pneumonia via inhibiting HOXA1., PMID:35018436
Long Noncoding RNA HOTAIRM1 Promotes Immunosuppression in Sepsis by Inducing T Cell Exhaustion., PMID:35022270
Homeobox A1 Facilitates Immune Escape and Alleviates Oxidative Stress in Lung Adenocarcinoma., PMID:35633885
HOXA1, a breast cancer oncogene., PMID:35675857
HOXA1 promotes proliferation and metastasis of bladder cancer by enhancing SMAD3 transcription., PMID:36228347
Circ_0058063 regulates the development of esophageal cancer through miR-377-3p/HOXA1 axis., PMID:36729977
Variations in the poly-histidine repeat motif of HOXA1 contribute to bicuspid aortic valve in mouse and zebrafish., PMID:36941270
HOXA1 promotes aerobic glycolysis and cancer progression in cervical cancer., PMID:37286120
Downregulation of homeobox A1 in human granulosa cells is involved in diminished ovarian reserve through promoting cell apoptosis and mitochondrial dysfunction., PMID:37923054
A retinoid analogue, TTNPB, promotes clonal expansion of human pluripotent stem cells by upregulating CLDN2 and HoxA1., PMID:38365890
HOXA1 silencing inhibits cisplatin resistance of oral squamous cell carcinoma cells via IκB/NF-κB signaling pathway., PMID:38477942
HOXA1 Promotes Migration, Invasion and Cell Cycle, and Suppresses Cisplatin Sensitivity of Laryngeal Cancer Cells By Mediating AKT/mTOR Pathway., PMID:39085122
HOXA1 promotes epithelial-mesenchymal transition and malignant characteristics of laryngeal squamous cell carcinoma., PMID:39243570
The homeobox family gene signature predicts the prognosis of osteosarcoma and correlates with immune invasion., PMID:39762460
Homeodomain Involvement in Nuclear HOX Protein Homo- and Heterodimerization., PMID:39796276
HOXA1 Contributes to Bronchial Epithelial Cell Cycle Progression by Regulating p21/CDKN1A., PMID:40076953
Role of Homeobox A1 in Airway Epithelial Generation from Human Airway Basal Cells., PMID:40214503