Catalog No.
YHH17501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly205-Asp291
Predicted molecular weight
12.79 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q15723
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NERF, New ETS-related factor, E74-like factor 2, ETS-related transcription factor Elf-2, ELF2
Note
For research use only.
Vitamin C modulates the metabolic and cytokine profiles, alleviates hepatic endoplasmic reticulum stress, and increases the life span of Gulo-/- mice., PMID:26922388
ChIP-on-chip analysis of thyroid hormone-regulated genes and their physiological significance., PMID:26968954
Supplementation of procyanidins B2 attenuates photooxidation-induced apoptosis in ARPE-19 cells., PMID:27251367
Salubrinal improves mechanical properties of the femur in osteogenesis imperfecta mice., PMID:27743814
Obovatol Induces Apoptosis in Non-small Cell Lung Cancer Cells via C/EBP Homologous Protein Activation., PMID:27489231
Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma., PMID:28096186
The antiproliferative ELF2 isoform, ELF2B, induces apoptosis in vitro and perturbs early lymphocytic development in vivo., PMID:28351373
An Elf2-like transcription factor acts as repressor of the mouse ecto-5'-nucleotidase gene expression in hepatic myofibroblasts., PMID:28667437
Long non-coding RNA PCAT7 regulates ELF2 signaling through inhibition of miR-134-5p in nasopharyngeal carcinoma., PMID:28728844
Phospho-Rasputin Stabilization by Sec16 Is Required for Stress Granule Formation upon Amino Acid Starvation., PMID:28746877
Highly Pathogenic New World Arenavirus Infection Activates the Pattern Recognition Receptor Protein Kinase R without Attenuating Virus Replication in Human Cells., PMID:28794024
Environmental perturbations lead to extensive directional shifts in RNA processing., PMID:29023442
Structure of a human cap-dependent 48S translation pre-initiation complex., PMID:29401259
Optimized postconditioning algorithm protects liver graft after liver transplantation in rats., PMID:29428101
Expression profile of translation initiation factor eIF2B5 in diffuse large B-cell lymphoma and its correlation to clinical outcome., PMID:30190479
Regional Susceptibility to ER Stress and Protection by Salubrinal Following a Single Exposure to Deltamethrin., PMID:30247739
Silvestrol Inhibits Chikungunya Virus Replication., PMID:30380742
B-Cell Receptor-Associated Protein 31 Regulates the Expression of Valosin-Containing Protein Through Elf2., PMID:30504720
Estrogen-Induced Apoptosis in Breast Cancers Is Phenocopied by Blocking Dephosphorylation of Eukaryotic Initiation Factor 2 Alpha (eIF2α) Protein., PMID:30655322
Expression of ELF1, a lymphoid ETS domain-containing transcription factor, is recurrently lost in classical Hodgkin lymphoma., PMID:30681722
Immunogenicity and Protective Efficacy of T-Cell Epitopes Derived From Potential Th1 Stimulatory Proteins of Leishmania (Leishmania) donovani., PMID:30873164
HNRNPAB-regulated lncRNA-ELF209 inhibits the malignancy of hepatocellular carcinoma., PMID:31090062
Major Effect of Oxidative Stress on the Male, but Not Female, SP-A1 Type II Cell miRNome., PMID:31354704
Identification of murine gammaherpesvirus 68 miRNA-mRNA hybrids reveals miRNA target conservation among gammaherpesviruses including host translation and protein modification machinery., PMID:31393953
Impact of High Salt Diet on Cerebral Vascular Function and Stroke in Tff3-/-/C57BL/6N Knockout and WT (C57BL/6N) Control Mice., PMID:31635131
miR-21-5p Under-Expression in Patients with Obstructive Sleep Apnea Modulates Intermittent Hypoxia with Re-Oxygenation-Induced-Cell Apoptosis and Cytotoxicity by Targeting Pro-Inflammatory TNF-α-TLR4 Signaling., PMID:32028672
CircRNA ZNF609 Knockdown Suppresses Cell Growth via Modulating miR-188/ELF2 Axis in Nasopharyngeal Carcinoma., PMID:32273713
Stromal Cell-Derived Factor (SDF) 2 and the Endoplasmic Reticulum Stress Response of Trophoblast Cells in Gestational Diabetes Mellitus and In vitro Hyperglycaemic Condition., PMID:32504504
ATF4 activation promotes hepatic mitochondrial dysfunction by repressing NRF1-TFAM signalling in alcoholic steatohepatitis., PMID:33177163
Correction of eIF2-dependent defects in brain protein synthesis, synaptic plasticity, and memory in mouse models of Alzheimer's disease., PMID:33531382
Indicators of the molecular pathogenesis of virulent Newcastle disease virus in chickens revealed by transcriptomic profiling of spleen., PMID:34475461
Supplementing N-carbamoylglutamate in late gestation increases newborn calf weight by enhanced placental expression of mTOR and angiogenesis factor genes in dairy cows., PMID:34738028
Secreted protein markers in oral squamous cell carcinoma (OSCC)., PMID:35130834
Perspective: Modulating the integrated stress response to slow aging and ameliorate age-related pathology., PMID:35146440
Long non-coding RNA PRNCR1 promotes ovarian cancer cell proliferation, migration and invasion by targeting the miR-653-5p/ELF2 axis., PMID:35166984
Serum From Preeclamptic Women Triggers Endoplasmic Reticulum Stress Pathway and Expression of Angiogenic Factors in Trophoblast Cells., PMID:35185601
Circ_0028007 Aggravates the Malignancy of Nasopharyngeal Carcinoma by Regulating miR-656-3p/ELF2 Axis., PMID:35239093
Translational control by heme-regulated elF2α kinase during erythropoiesis., PMID:35441596
Empagliflozin alleviates endoplasmic reticulum stress and augments autophagy in rotenone-induced Parkinson's disease in rats: Targeting the GRP78/PERK/eIF2α/CHOP pathway and miR-211-5p., PMID:35654124
Chemoproteomic profiling to identify activity changes and functional inhibitors of DNA-binding proteins., PMID:36356585
Barhi date (Phoenix dactylifera) extract ameliorates hepatocellular carcinoma in male rats., PMID:36411668
In silico analysis of alternative splicing events implicated in intracellular trafficking during B-lymphocyte differentiation., PMID:36439187
c-Myc-induced long noncoding RNA MIRE cooperates with hnRNPK to stabilize ELF2 mRNA and promotes clear cell renal cell carcinogenesis., PMID:37248433
A novel peptide P1-121aa encoded by STK24P1 regulates vasculogenic mimicry via ELF2 phosphorylation in glioblastoma., PMID:37406957
Hemopexin Reverses Activation of Lung eIF2a and Decreases Mitochondrial Injury in Chlorine Exposed Mice., PMID:37645744
Hemopexin reverses activation of lung eIF2α and decreases mitochondrial injury in chlorine-exposed mice., PMID:38150547
Combination of computational techniques and RNAi reveal targets in Anopheles gambiae for malaria vector control., PMID:38968330
CaMKKβ regulates transcription factor Elf2 gene methylation to maintain endothelial junctional barrier integrity., PMID:40060544
Therapeutic application of nano-encapsulated pomegranate peel extract attenuated DSS-induced colitis: Antioxidant and anti-inflammatory role and reduction of exaggerated response of endoplasmic reticulum stress., PMID:40359212
Identification of candidate transcription factors that regulate Sox9 expression through the testis-specific enhancer in the Amami spiny rat (Tokudaia osimensis), an XO/XO mammal., PMID:40467489
For research use only. Not for human or drug use.
