Catalog No.
YHK56701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Lys163
Predicted molecular weight
19.71 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q6FI81
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Cytokine-induced apoptosis inhibitor 1, Anamorsin, Fe-S cluster assembly protein DRE2 homolog, CIAPIN1
CIAPIN1 promotes proliferation and migration of PDGF-BB-activated airway smooth muscle cells via the PI3K/AKT and JAK2/STAT3 signaling pathways., PMID:40338178
CIAPIN1 attenuates ferroptosis via regulating PI3K/AKT pathway in LPS-induced podocytes., PMID:40259237
Causal associations between circulating protein ratios and drug resistance in papillary thyroid cancer: a Mendelian randomization study., PMID:39754686
Downregulation of CIAPIN1 regulates the proliferation, migration and glycolysis of breast cancer cells via inhibition of STAT3 pathway., PMID:39242716
Serum CIAPIN1 is lower in septic patients with cardiac dysfunction., PMID:39241831
Omics-CNN: A comprehensive pipeline for predictive analytics in quantitative omics using one-dimensional convolutional neural networks., PMID:38027840
Cytokine-induced apoptosis inhibitor 1: a comprehensive analysis of potential diagnostic, prognosis, and immune biomarkers in invasive breast cancer., PMID:37588751
Tat-CIAPIN1 Prevents Pancreatic β-Cell Death in hIAPP-Induced RINm5F Cells and T2DM Animal Model., PMID:37445656
The expression of cuproptosis-related genes in hepatocellular carcinoma and their relationships with prognosis., PMID:36313717
Prediction of CIAPIN1 (Cytokine-Induced Apoptosis Inhibitor 1) Signaling Pathway and Its Role in Cholangiocarcinoma Metastasis., PMID:35807116
Cytokine-induced apoptosis inhibitor 1 (CIAPIN1) accelerates vascular remodelling via p53 and JAK2-STAT3 regulation in vascular smooth muscle cells., PMID:34289085
Tat-CIAPIN1 protein prevents against cytokine-induced cytotoxicity in pancreatic RINm5F β-cells., PMID:34120676
In Cellulo Mössbauer and EPR Studies Bring New Evidence to the Long-Standing Debate on Iron-Sulfur Cluster Binding in Human Anamorsin., PMID:33852169
Inhibition of miR-322-5p Protects Cardiac Myoblast Cells Against Hypoxia-Induced Apoptosis and Injury Through Regulating CIAPIN1., PMID:33538533
Autoantibody signature in hepatocellular carcinoma using seromics., PMID:32616055
Re-Evaluating the Mechanism of Action of α,β-Unsaturated Carbonyl DUB Inhibitors b-AP15 and VLX1570: A Paradigmatic Example of Unspecific Protein Cross-linking with Michael Acceptor Motif-Containing Drugs., PMID:32109059
Transduced Tat-CIAPIN1 reduces the inflammatory response on LPS- and TPA-induced damages., PMID:31722779
New prognostic markers revealed by RNA-Seq transcriptome analysis after MYC silencing in a metastatic gastric cancer cell line., PMID:31645899
Anamorsin attenuates cupric chloride-induced dopaminergic neuronal cell death., PMID:31582212
Downregulation of miR‑16 protects H9c2(2‑1) cells against hypoxia/reoxygenation damage by targeting CIAPIN1 and regulating the NF‑κB pathway., PMID:31432171
CIAPIN1 Targeted NHE1 and ERK1/2 to Suppress NSCLC Cells' Metastasis and Predicted Good Prognosis in NSCLC Patients Receiving Pulmonectomy., PMID:31093311
Tat-CIAPIN1 inhibits hippocampal neuronal cell damage through the MAPK and apoptotic signaling pathways., PMID:30818058
MiRNA-195-5p Functions as a Tumor Suppressor and a Predictive of Poor Prognosis in Non-small Cell Lung Cancer by Directly Targeting CIAPIN1., PMID:30637589
OsDRE2 contributes to chitin-triggered response through its interaction with OsRLCK185., PMID:30418086
Hsa-miRNA-143-3p Reverses Multidrug Resistance of Triple-Negative Breast Cancer by Inhibiting the Expression of Its Target Protein Cytokine-Induced Apoptosis Inhibitor 1 In Vivo., PMID:30275853
Inhibition of miR-182-5p protects cardiomyocytes from hypoxia-induced apoptosis by targeting CIAPIN1., PMID:29671338
The study on expression of CIAPIN1 interfering hepatocellular carcinoma cell proliferation and its mechanisms., PMID:28742201
Anamorsin/Ndor1 Complex Reduces [2Fe-2S]-MitoNEET via a Transient Protein-Protein Interaction., PMID:28648056
Upregulation of microRNA-143 reverses drug resistance in human breast cancer cells via inhibition of cytokine-induced apoptosis inhibitor 1., PMID:28588724
NBP35 interacts with DRE2 in the maturation of cytosolic iron-sulphur proteins in Arabidopsis thaliana., PMID:27801963
Cytokine-induced apoptosis inhibitor-1 causes dedifferentiation of rabbit articular chondrocytes via the ERK-1/2 and p38 kinase pathways., PMID:27644154
EPR studies of wild type and mutant Dre2 identify essential [2Fe--2S] and [4Fe--4S] clusters and their cysteine ligands., PMID:27672211
A Glutaredoxin·BolA Complex Serves as an Iron-Sulfur Cluster Chaperone for the Cytosolic Cluster Assembly Machinery., PMID:27519415
Knock-down of CIAPIN1 sensitizes K562 chronic myeloid leukemia cells to Imatinib by regulation of cell cycle and apoptosis-associated members via NF-κB and ERK5 signaling pathway., PMID:26679828
Elucidating the Molecular Function of Human BOLA2 in GRX3-Dependent Anamorsin Maturation Pathway., PMID:26613676
Cancer-Related NEET Proteins Transfer 2Fe-2S Clusters to Anamorsin, a Protein Required for Cytosolic Iron-Sulfur Cluster Biogenesis., PMID:26448442
[Expression of cytokine-induced apoptosis inhibitor 1 in gastric cancer tissues and its effects on invasion and migration of SGC-7901 cell]., PMID:26404695
N-terminal domains mediate [2Fe-2S] cluster transfer from glutaredoxin-3 to anamorsin., PMID:26302480
Molecular cloning, expression and functional characterization of a teleostan cytokine-induced apoptosis inhibitor from rock bream (Oplegnathus fasciatus)., PMID:25912359
Cytokine-induced apoptosis inhibitor 1 inhibits the growth and proliferation of multiple myeloma., PMID:25901506
CIAPIN1 and ABCA13 are markers of poor survival in metastatic ovarian serous carcinoma., PMID:25889687
CIAPIN1 targets Na⁺/H⁺ exchanger 1 to mediate MDA-MB-231 cells' metastasis through regulation of MMPs via ERK1/2 signaling pathway., PMID:25724898
Epigenetic role for the conserved Fe-S cluster biogenesis protein AtDRE2 in Arabidopsis thaliana., PMID:25197096
CIAPIN1 targets Na+/H+ exchanger 1 to mediate K562 chronic myeloid leukemia cells' differentiation via ERK1/2 signaling pathway., PMID:25043809
The diabetes drug target MitoNEET governs a novel trafficking pathway to rebuild an Fe-S cluster into cytosolic aconitase/iron regulatory protein 1., PMID:25012650
[Effect of CIAPIN1 gene on proliferation of K562 cells]., PMID:24989274
Anamorsin, a novel caspase-3 substrate in neurodegeneration., PMID:24973211
CIAPIN1 gene silencing enhances chemosensitivity in a drug-resistant animal model in vivo., PMID:24676475
The anti-apoptotic gene Anamorsin is essential for both autonomous and extrinsic regulation of murine fetal liver hematopoiesis., PMID:24440520
Proteomic studies of multiple myeloma in RPMI8226 cell line treated with bendamustine., PMID:24344029
For research use only. Not for human or drug use.
