Catalog No.
YHH86901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser207-Ser434
Predicted molecular weight
28.01 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q53EU6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
1-acyl-sn-glycerol-3-phosphate O-acyltransferase 9, AGPAT 10, 1-AGPAT 9, GPAT-3, hGPAT3, Glycerol-3-phosphate acyltransferase 3, Lysophosphatidic acid acyltransferase theta, 1-acyl-sn-glycerol-3-phosphate O-acyltransferase 10, LPAAT-theta, Acyl-CoA:glycerol-3-phosphate acyltransferase 3, 1-AGP acyltransferase 9, Lung cancer metastasis-associated protein 1, MAG1, MAG-1, GPAT3, AGPAT9
Integrated Metabolomics and Lipidomics Analysis Reveals the Mechanism Behind the Action of Chiglitazar on the Protection Against Sepsis-Induced Acute Lung Injury., PMID:40422869
JNK mediates serine phosphorylation of STAT3 in response to fatty acids released by lipolysis., PMID:40092442
Disruption of the endoplasmic reticulum-localized fatty acyl-ACP thioesterase IPF1 caused partial male sterility in rice., PMID:40056293
Isolation and Characterization of GPAT3 Gene from Jojoba Plant and its Inferior Early Diagnosis of Sex., PMID:39820567
Understanding the triacylglycerol-based carbon anabolic differentiation in Cyperus esculentus and Cyperus rotundus developing tubers via transcriptomic and metabolomic approaches., PMID:39731027
FSH increases lipid droplet content by regulating the expression of genes related to lipid storage in Rat Sertoli cells., PMID:39490730
Multi-omics characterization of type 2 diabetes mellitus-induced gastroenteropathy in the db/db mouse model., PMID:39211388
GPAT3 is a potential therapeutic target to overcome sorafenib resistance in hepatocellular carcinoma., PMID:38948063
PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression., PMID:38309267
GPAT3 deficiency attenuates corticosterone-caused hepatic steatosis and oxidative stress through GSK3β/Nrf2 signals., PMID:38185063
Identification of genomic regions, genetic variants and gene networks regulating candidate genes for lipid metabolism in pig muscle., PMID:38064855
Si-Ni-San reverses dietary fat absorption defects in a murine model of depression., PMID:37857252
1-Oleoyl-lysophosphatidylethanolamine stimulates RORγt activity in TH17 cells., PMID:37540735
GPAT3 regulates the synthesis of lipid intermediate LPA and exacerbates Kupffer cell inflammation mediated by the ERK signaling pathway., PMID:36964139
The Heat Shock Transcription Factor PtHSF1 Mediates Triacylglycerol and Fucoxanthin Synthesis by Regulating the Expression of GPAT3 and DXS in Phaeodactylum tricornutum., PMID:36947404
A study of congenital generalized lipodystrophy (CGL) caused by BSCL2 gene mutation., PMID:36384728
Genome-wide association analysis of milk production, somatic cell score, and body conformation traits in Holstein cows., PMID:36268046
Human placental lipid content and lipid metabolic enzyme abundance in obesity and across gestation., PMID:36103262
Evidence from transcriptome analysis unravelled the roles of eyestalk in salinity adaptation in Pacific white shrimp (Litopenaeus vannamei)., PMID:36055397
Integrated lipidomics and RNA sequencing analysis reveal novel changes during 3T3-L1 cell adipogenesis., PMID:35529487
The Integrated Analysis of Transcriptomics and Metabolomics Unveils the Therapeutical Effect of Asiatic Acid on Alcoholic Hepatitis in Rats., PMID:35348973
N-Acetylcysteine alleviates high fat diet-induced hepatic steatosis and liver injury via regulating the intestinal microecology in mice., PMID:35229847
Mycobacterium leprae promotes triacylglycerol de novo synthesis through induction of GPAT3 expression in human premonocytic THP-1 cells., PMID:33770127
Identification of a promoter polymorphism affecting GPAT3 gene expression that is likely related to intramuscular fat content in pigs., PMID:33345707
Nuclear lipid droplets form in the inner nuclear membrane in a seipin-independent manner., PMID:33315072
Triacylglycerol synthesis directed by glycerol-3-phosphate acyltransferases -3 and -4 is required for lipid droplet formation and the modulation of the inflammatory response during macrophage to foam cell transition., PMID:33260006
Identification of a metabolism-related gene expression prognostic model in endometrial carcinoma patients., PMID:32894095
Oligomers of the lipodystrophy protein seipin may co-ordinate GPAT3 and AGPAT2 enzymes to facilitate adipocyte differentiation., PMID:32094408
Folic acid supplementation regulates milk production variables, metabolic associated genes and pathways in perinatal Holsteins., PMID:31994802
GPAT3 deficiency alleviates insulin resistance and hepatic steatosis in a mouse model of severe congenital generalized lipodystrophy., PMID:31873720
Rosiglitazone remodels the lipid droplet and britens human visceral and subcutaneous adipocytes ex vivo., PMID:30782959
OsGPAT3 Plays a Critical Role in Anther Wall Programmed Cell Death and Pollen Development in Rice., PMID:30545137
Glycerol-3-phosphate acyltransferases 3 and 4 direct glycerolipid synthesis and affect functionality in activated macrophages., PMID:30523059
Analysis of Time-Series Gene Expression Data to Explore Mechanisms of Chemical-Induced Hepatic Steatosis Toxicity., PMID:30279702
Genistein and daidzein induce apoptosis of colon cancer cells by inhibiting the accumulation of lipid droplets., PMID:29849534
AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity., PMID:29617643
Map-based cloning and characterization of Zea mays male sterility33 (ZmMs33) gene, encoding a glycerol-3-phosphate acyltransferase., PMID:29546443
Berberine increases adipose triglyceride lipase in 3T3-L1 adipocytes through the AMPK pathway., PMID:27938388
SEIPIN Regulates Lipid Droplet Expansion and Adipocyte Development by Modulating the Activity of Glycerol-3-phosphate Acyltransferase., PMID:27806294
Sunflower HaGPAT9-1 is the predominant GPAT during seed development., PMID:27717477
Real-Time Tracking of BODIPY-C12 Long-Chain Fatty Acid in Human Term Placenta Reveals Unique Lipid Dynamics in Cytotrophoblast Cells., PMID:27124483
Seapolynol Extracted from Ecklonia cava Inhibits Adipocyte Differentiation in Vitro and Decreases Fat Accumulation in Vivo., PMID:26690099
Characterization of a Novel Intestinal Glycerol-3-phosphate Acyltransferase Pathway and Its Role in Lipid Homeostasis., PMID:26644473
AGPAT9 suppresses cell growth, invasion and metastasis by counteracting acidic tumor microenvironment through KLF4/LASS2/V-ATPase signaling pathway in breast cancer., PMID:26110566
Maternal High-Fat Feeding Increases Placental Lipoprotein Lipase Activity by Reducing SIRT1 Expression in Mice., PMID:25948680
Thyrotropin and obesity: increased adipose triglyceride content through glycerol-3-phosphate acyltransferase 3., PMID:25559747
Transcriptome profiling identifies ABA mediated regulatory changes towards storage filling in developing seeds of castor bean (Ricinus communis L.)., PMID:25061509
Glycerol-3-phosphate acyltransferase-4-deficient mice are protected from diet-induced insulin resistance by the enhanced association of mTOR and rictor., PMID:24939733
The medial preoptic nucleus as a site of the thermogenic and metabolic actions of melanotan II in male rats., PMID:24808495
Preservation of hepatocyte nuclear factor-4α contributes to the beneficial effect of dietary medium chain triglyceride on alcohol-induced hepatic lipid dyshomeostasis in rats., PMID:23126616
For research use only. Not for human or drug use.
