Catalog No.
YHK55701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr47-Ala451
Predicted molecular weight
47.29 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q92823
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ng-CAM-related, KIAA0343, hBravo, NRCAM, NgCAM-related cell adhesion molecule, Neuronal cell adhesion molecule, Neuronal surface protein Bravo, Nr-CAM
Note
For research use only.
The transcriptomic profiling of SARS-CoV-2 compared to SARS, MERS, EBOV, and H1N1., PMID:33301474
AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion., PMID:33311477
Age-related transcriptome changes in melanoma patients with tumor-positive sentinel lymph nodes., PMID:33373316
Association of Candidate Single Nucleotide Polymorphisms Related to Candidate Genes in Patients With Schizophrenia., PMID:33643553
Antisense oligonucleotides targeting alternative splicing of Nrcam exon 10 suppress neurite outgrowth of ganglion sensory neurons in vitro., PMID:33850082
Semaphorin3F Drives Dendritic Spine Pruning Through Rho-GTPase Signaling., PMID:33856648
A Preliminary Investigation on Plasma Cell Adhesion Molecules Levels by Protein Microarray Technology in Major Depressive Disorder., PMID:33912082
Cadmium-mediated pancreatic islet transcriptome changes in mice and cultured mouse islets., PMID:34666113
[Preliminary study on cerebrospinal fluid proteomics of Erxian Decoction against neurogenesis impairment in late-onset depression]., PMID:34951250
Bi-allelic variants in neuronal cell adhesion molecule cause a neurodevelopmental disorder characterized by developmental delay, hypotonia, neuropathy/spasticity., PMID:35108495
Serum molecular biomarkers in neuromyelitis optica and multiple sclerosis., PMID:35172264
LncRNA RUNX1-IT1 affects the differentiation of Th1 cells by regulating NrCAM transcription in Graves' disease., PMID:35220890
NrCAM secreted by endometrial stromal cells enhances the progestin sensitivity of endometrial cancer cells through epigenetic modulation of PRB., PMID:35388173
Proteomic analysis of autoimmune retinopathy implicates NrCAM as a potential biomarker., PMID:35529077
NRCAM acts as a prognostic biomarker and promotes the tumor progression in gastric cancer via EMT pathway., PMID:35763884
Crystal structure of Ankyrin-G in complex with a fragment of Neurofascin reveals binding mechanisms required for integrity of the axon initial segment., PMID:35850303
Differential Gene Expression in Sporadic and Genetic Forms of Alzheimer's Disease and Frontotemporal Dementia in Brain Tissue and Lymphoblastoid Cell Lines., PMID:35962298
Large-scale transcriptomic analysis of coding and non-coding pathological biomarkers, associated with the tumor immune microenvironment of thyroid cancer and potential target therapy exploration., PMID:35990603
Doublecortin-Like Kinase 1 Facilitates Dendritic Spine Growth of Pyramidal Neurons in Mouse Prefrontal Cortex., PMID:36064052
The Potential Role of Serum Tau Protein (MAPT), Neuronal Cell Adhesion Molecule (NrCAM) and Neprilysin (NEP) in Neurodegenerative Disorders Development in Psoriasis-Preliminary Results., PMID:36078974
Stress-induced headache in the general working population is moderated by the NRCAM rs2300043 genotype., PMID:36181733
Investigation of 91 proteins implicated in neurobiological processes identifies multiple candidate plasma biomarkers of stroke outcome., PMID:36418382
Investigating SH-SY5Y Neuroblastoma Cell Surfaceome as a Model for Neuronal-Targeted Novel Therapeutic Modalities., PMID:36499391
Bi-allelic loss of function variant in the NRCAM gene is associated with motor-predominant axonal polyneuropathy; the second report., PMID:36606341
Perinatal mood and anxiety disorders: biomarker discovery using plasma proteomics., PMID:36649818
Antibody-directed extracellular proximity biotinylation reveals Contactin-1 regulates axo-axonic innervation of axon initial segments., PMID:36945454
Association of muscular strength and targeted proteomics involved in brain health in children with overweight/obesity., PMID:37190796
Towards a human brain EV atlas: Characteristics of EVs from different brain regions, including small RNA and protein profiles., PMID:37214955
Exome sequencing findings in children with annular pancreas., PMID:37635636
Multiomic analysis implicates FOXO4 in genetic regulation of chick lens fiber cell differentiation., PMID:37722500
Antibody-directed extracellular proximity biotinylation reveals that Contactin-1 regulates axo-axonic innervation of axon initial segments., PMID:37884508
Liver cancer stem cell dissemination and metastasis: uncovering the role of NRCAM in hepatocellular carcinoma., PMID:37993901
Toward a human brain extracellular vesicle atlas: Characteristics of extracellular vesicles from different brain regions, including small RNA and protein profiles., PMID:38089920
Alpha-synuclein promotes PRMT5-mediated H4R3me2s histone methylation by interacting with the BAF complex., PMID:38105619
Rbfox1 regulates alternative splicing of Nrcam in primary sensory neurons to mediate peripheral nerve injury-induced neuropathic pain., PMID:38241164
CircNRCAM up-regulates NRCAM to promote papillary thyroid carcinoma progression., PMID:38485895
Genetic alterations in the neuronal development genes are associated with changes of the tumor immune microenvironment in pancreatic cancer., PMID:38495381
NrCAM-deficient mice exposed to chronic stress exhibit disrupted latent inhibition, a hallmark of schizophrenia., PMID:38601326
Following the p63/Keratin5 basal cells in the sensory and non-sensory epithelia of the vomeronasal organ., PMID:38665067
miR-153 promotes neural differentiation by activating the cell adhesion/Ca2+ signaling pathway and targeting ion channel activity in HT-22 cells by bioinformatic analysis., PMID:38694121
Construction of a ceRNA network and screening of potential biomarkers and molecular targets in male smokers with chronic obstructive pulmonary disease., PMID:38933922
Ankyrin-B is required for the establishment and maintenance of lens cytoarchitecture, mechanics, and clarity., PMID:38952798
NrCAM activates the NF-κB signalling pathway by competitively binding to SUMO-1 and promotes Th17 cell differentiation in Graves' disease., PMID:39155774
Identification and validation of diagnostic genes associated with neutrophil extracellular traps of type 2 diabetes mellitus., PMID:39296548
Novel plasma protein biomarkers: A time-dependent predictive model for Alzheimer's disease., PMID:39427525
Ankyrin-B is required for the establishment and maintenance of lens cytoarchitecture, mechanics and clarity., PMID:39558792
Regulation of Perisomatic Synapses from Cholecystokinin Basket Interneurons through NrCAM and Ankyrin B., PMID:39574611
Neuronal cell adhesion molecule (NRCAM) variant defined by microexon skipping is an essential, antigenically distinct, and targetable proteoform in high-grade glioma., PMID:39868324
Regulation of perisomatic synapses from cholecystokinin basket interneurons through NrCAM and Ankyrin B., PMID:40276719
Astrogliosis Occurs Selectively in Amygdala of Adolescent Primate and Rodent Following Daily Δ9-Tetrahydrocannabinol, Prevented by Cannabidiol Co-Treatment., PMID:40487783
For research use only. Not for human or drug use.
