Catalog No.
YHK55401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp8-Lys193
Predicted molecular weight
24.49 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9GZM8
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Protein Nudel, EOPA, Nuclear distribution protein nudE-like 1, NUDEL, MITAP1, NDEL1, Mitosin-associated protein 1
Note
For research use only.
Cep128 associates with Odf2 to form the subdistal appendage of the centriole., PMID:30623524
Regulation of in vivo dynein force production by CDK5 and 14-3-3ε and KIAA0528., PMID:30651536
Ndel1 oligopeptidase activity as a potential biomarker of early stages of schizophrenia., PMID:30857875
NFAT1-Mediated Regulation of NDEL1 Promotes Growth and Invasion of Glioma Stem-like Cells., PMID:30940662
Isolation of nanobodies against Xenopus embryonic antigens using immune and non-immune phage display libraries., PMID:31048885
Exercise ameliorates deficits in neural microstructure in a Disc1 model of psychiatric illness., PMID:31103832
Neuropeptides and oligopeptidases in schizophrenia., PMID:31794779
Sequential phosphorylation of NDEL1 by the DYRK2-GSK3β complex is critical for neuronal morphogenesis., PMID:31815665
Mechanistic insights into the interactions of dynein regulator Ndel1 with neuronal ankyrins and implications in polarity maintenance., PMID:31889000
Mapping axon initial segment structure and function by multiplexed proximity biotinylation., PMID:31900387
Decreased nuclear distribution nudE-like 1 enzyme activity in an animal model with dysfunctional disrupted-in-schizophrenia 1 signaling featuring aberrant neurodevelopment and amphetamine-supersensitivity., PMID:31916893
Reelin Improves Cognition and Extends the Lifespan of Mutant Ndel1 Mice with Postnatal CA1 Hippocampus Deterioration., PMID:32328622
Role of NDEL1 and VEGF/VEGFR-2 in Mouse Hippocampus After Status Epilepticus., PMID:32423231
Nuclear Respiratory Factor 1 (NRF1) Transcriptional Activity-Driven Gene Signature Association with Severity of Astrocytoma and Poor Prognosis of Glioblastoma., PMID:32594352
Arsenic trioxide disturbs the LIS1/NDEL1/dynein microtubule dynamic complex by disrupting the CLIP170 zinc finger in head and neck cancer., PMID:32717241
Postnatal Role of the Cytoskeleton in Adult Epileptogenesis., PMID:32864616
Evaluation of NDEL1 oligopeptidase activity in blood and brain in an animal model of schizophrenia: effects of psychostimulants and antipsychotics., PMID:33116174
Loss of ESRP1 blocks mouse oocyte development and leads to female infertility., PMID:33318146
Expression and function of Ndel1 during the differentiation of neural stem cells induced by hippocampal exosomesticle., PMID:33422130
Use of Primary Cultured Hippocampal Neurons to Study the Assembly of Axon Initial Segments., PMID:33645578
Regulation of monoamine levels by typical and atypical antipsychotics in Caenorhabditis elegans mutant for nuclear distribution element genes., PMID:33872680
miR-103-3p targets Ndel1 to regulate neural stem cell proliferation and differentiation., PMID:34269216
Roles for Ndel1 in keratin organization and desmosome function., PMID:34319758
Nde1 is a Rab9 effector for loading late endosomes to cytoplasmic dynein motor complex., PMID:34793709
Conformational heterogeneity coupled with β-fibril formation of a scaffold protein involved in chronic mental illnesses., PMID:34921141
The Cytoplasmic Dynein Associated Protein NDE1 Regulates Osteoclastogenesis by Modulating M-CSF and RANKL Signaling Pathways., PMID:35011575
Responsible Genes for Neuronal Migration in the Chromosome 17p13.3: Beyond Pafah1b1(Lis1), Crk and Ywhae(14-3-3ε)., PMID:35053800
LIS1 and NDEL1 Regulate Axonal Trafficking of Mitochondria in Mature Neurons., PMID:35465088
Nde1 and Ndel1: Outstanding Mysteries in Dynein-Mediated Transport., PMID:35493069
Sequential accumulation of dynein and its regulatory proteins at the spindle region in the Caenorhabditis elegans embryo., PMID:35817834
Unraveiling the correlation among neurodevelopmental and inflammatory biomarkers in patients with chronic schizophrenia., PMID:36189960
LRRK1-mediated NDEL1 phosphorylation promotes cilia disassembly via dynein-2-driven retrograde intraflagellar transport., PMID:36254578
Aurora A phosphorylates Ndel1 to reduce the levels of Mad1 and NuMA at spindle poles., PMID:36350697
Ndel1 modulates dynein activation in two distinct ways., PMID:36747695
Gcap14 is a microtubule plus-end-tracking protein coordinating microtubule-actin crosstalk during neurodevelopment., PMID:36795749
Effects of representative point mutations on dynamic behavior of the DISC1-Ndel1 complex: a molecular dynamics study., PMID:36858606
Dynein at the kinetochore., PMID:36861883
Ndel1 disfavors dynein-dynactin-adaptor complex formation in two distinct ways., PMID:37086789
Assessing the role of Ndel1 oligopeptidase activity in congenital Zika syndrome: Potential predictor of congenital syndrome endophenotype and treatment response., PMID:37497817
Conserved roles for the dynein intermediate chain and Ndel1 in assembly and activation of dynein., PMID:37730751
Identification of an ex vivo inhibitor of the schizophrenia biomarker Ndel1 by high throughput screening., PMID:37820964
Nde1 promotes Lis1-mediated activation of dynein., PMID:37940657
Differential transcript usage across mammalian oocytes at the germinal vesicle and metaphase II stages., PMID:37995439
miR-134-3p driven by anisomycin impairs ovarian cancer stem cell activity through inhibiting GPR137 expression., PMID:38021163
Novel lissencephaly-associated NDEL1 variant reveals distinct roles of NDE1 and NDEL1 in nucleokinesis and human cortical malformations., PMID:38194050
Dynein and dynactin move long-range but are delivered separately to the axon tip., PMID:38407313
CCSer2 gates dynein activity at the cell periphery., PMID:38915497
Investigation into the molecular mechanisms of biomarkers in psoriasis vulgaris with reduced high-density lipoprotein levels based on bulk transcriptome sequencing data., PMID:39732346
CCSer2 gates dynein activity at the cell periphery., PMID:40261303
Tracing the aggregation pathway of the scaffold protein DISC1: Structural implications for chronic mental illnesses., PMID:40503182
For research use only. Not for human or drug use.
