Catalog No.
YHE00501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser407-Glu718
Predicted molecular weight
36.97 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P32418
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CNC, Sodium/calcium exchanger 1, Na(+)/Ca(2+)-exchange protein 1, Solute carrier family 8 member 1, NCX1, SLC8A1
Note
For research use only.
NF-κB-mediated inflammation correlates with calcium overload under arsenic trioxide-induced myocardial damage in Gallus gallus., PMID:28728119
Urotensin 2 in Kawasaki disease pathogenesis., PMID:28753597
Mapping the in vitro interactome of cardiac sodium (Na+ )-calcium (Ca2+ ) exchanger 1 (NCX1)., PMID:28755400
Arrhythmogenic gene remodelling in elderly patients with type 2 diabetes with aortic stenosis and normal left ventricular ejection fraction., PMID:28804970
Genetic Variation in SLC8A1 Gene Involved in Blood Pressure Responses to Acute Salt Loading., PMID:29182730
Associations between genetic polymorphisms of membrane transporter genes and prognosis after chemotherapy: meta-analysis and finding from Seoul Breast Cancer Study (SEBCS)., PMID:29618765
Polycystin-1 dysfunction impairs electrolyte and water handling in a renal precystic mouse model for ADPKD., PMID:29767557
LncRNA SLC8A1-AS1 protects against myocardial damage through activation of cGMP-PKG signaling pathway by inhibiting SLC8A1 in mice models of myocardial infarction., PMID:30378115
Associations between olfactory pathway gene methylation marks, obesity features and dietary intakes., PMID:31057674
Targeting the highly abundant circular RNA circSlc8a1 in cardiomyocytes attenuates pressure overload induced hypertrophy., PMID:31114845
Endolymphatic hydrops and ionic transporters: genetic and biohumoral aspects., PMID:31165925
Circular RNA circSLC8A1 acts as a sponge of miR-130b/miR-494 in suppressing bladder cancer progression via regulating PTEN., PMID:31228937
On the special role of NCX in astrocytes: Translating Na+-transients into intracellular Ca2+ signals., PMID:31901681
Transcriptome analysis and identification of genes associated with chicken sperm storage duration., PMID:32036969
NCX1 represents an ionic Na+ sensing mechanism in macrophages., PMID:32569301
Circ-SLC8A1 regulates osteoporosis through blocking the inhibitory effect of miR-516b-5p on AKAP2 expression., PMID:32830397
LncRNA ZNF503-AS1 acts as a tumor suppressor in bladder cancer by up-regulating Ca2+ concentration via transcription factor GATA6., PMID:33001357
Integrated traditional Chinese medicine alleviates sciatica while regulating gene expression in peripheral blood., PMID:33573686
Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4., PMID:33629929
Transcriptomics Analysis Identifies the Presence of Upregulated Ribosomal Housekeeping Genes in the Alveolar Macrophages of Patients with Smoking-Induced Chronic Obstructive Pulmonary Disease., PMID:34588774
Circular RNA circSLC8A1 inhibits the proliferation and invasion of non-small cell lung cancer cells through targeting the miR-106b-5p /FOXJ3 axis., PMID:34724864
Association of Circulating Biomarkers of lnc-IGSF3-1:1, SCOC-AS1, and SLC8A1-AS1 with Salt Sensitivity of Blood Pressure in Chinese Population., PMID:34855149
SLC8A1 antisense RNA 1 suppresses papillary thyroid cancer malignant progression via the FUS RNA binding protein (FUS)/NUMB like endocytic adaptor protein (Numbl) axis., PMID:35599603
A novel SLC8A1/LINC01913 intergenic region-ALK fusion identified by NGS and validated by IHC and FISH in a stage IIB lung adenocarcinoma patient who remains relapse-free during the treatment of crizotinib: a case report., PMID:35666357
Silencing lncRNA 93358 Inhibits the Apoptosis of Myocardial Cells in Myocardial Infarction Rats by Inducing the Expression of SLC8A1., PMID:35845941
Functional Characterization of Human Induced Pluripotent Stem Cell-Derived Endothelial Cells., PMID:35955642
Excellent response of lung adenocarcinoma harboring a rare SLC8A1 downstream intergenic region ALK fusion to ceritinib treatment: A case report., PMID:36042596
A novel SLC8A1-ALK fusion in lung adenocarcinoma confers sensitivity to alectinib: A case report., PMID:36045716
Silencing mouse circular RNA circSlc8a1 by circular antisense cA-circSlc8a1 induces cardiac hepatopathy., PMID:36245125
RBPMS2 Is a Myocardial-Enriched Splicing Regulator Required for Cardiac Function., PMID:36367103
Integration of metabolomics and transcriptomics provides insights into enhanced osteogenesis in Ano5Cys360Tyr knock-in mouse model., PMID:36742392
Association of polymorphisms of calcium reabsorption genes SLC12A1, KCNJ1 and SLC8A1 with colorectal adenoma., PMID:37074453
Downregulation of FKBP5 Promotes Atrial Arrhythmogenesis., PMID:37154033
The impact of rare protein coding genetic variation on adult cognitive function., PMID:37231097
Palmitoylation of solute carriers., PMID:37481134
Circular RNA SLC8A1 triggers hippocampal neuronal ferroptosis by regulating FUS-mediated ATF3 mRNA stability in epilepsy., PMID:37918704
LKB1-SIK2 loss drives uveal melanoma proliferation and hypersensitivity to SLC8A1 and ROS inhibition., PMID:37966164
Gene Expression Profiling of Post Mortem Midbrain of Parkinson's Disease Patients and Healthy Controls., PMID:38255780
circRNA_SLC8A1 promotes the survival of mycobacterium tuberculosis in macrophages by upregulating expression of autophagy-related protein SQSTM1/p62 to activate the NF-κB pathway., PMID:38433218
Author Correction: circRNA_SLC8A1 promotes the survival of mycobacterium tuberculosis in macrophages by upregulating expression of autophagy-related protein SQSTM1/p62 to activate the NF-κB pathway., PMID:38632347
Cardiac function is regulated by the sodium-dependent inhibition of the sodium-calcium exchanger NCX1., PMID:38714663
Cardiac stereotactic body radiotherapy to treat malignant ventricular arrhythmias directly affects the cardiomyocyte electrophysiology., PMID:38936449
Voltage-gated ion channel's gene expression in the myocardium of embryo and adult chickens., PMID:39127438
Familial juvenile hyperuricemic nephropathy: Revisiting the SLC8A1 gene, in a family with a novel terminal gross deletion in the UMOD gene., PMID:39216982
CircRNA_SLC8A1 alleviates hypertrophic scar progression by mediating the Nrf2-ARE pathway., PMID:39422836
In-Depth Proteomic Analysis of Paraffin-Embedded Tissue Samples from Colorectal Cancer Patients Revealed TXNDC17 and SLC8A1 as Key Proteins Associated with the Disease., PMID:39441737
Brain multi-omic Mendelian randomisation to identify novel drug targets for gliomagenesis., PMID:39565278
The inhibition of SLC8A1 promotes Ca2+-dependent cell death in Gastric Cancer., PMID:39731939
The characterization of uterine calcium transport and metabolism during eggshell calcification of hens laying high or low breaking strength eggshell., PMID:40222347
A new protein isoform encoded by human circular RNA circSLC8a1 contributes to cardiac remodelling., PMID:40273295
For research use only. Not for human or drug use.
