Catalog No.
YHH09001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Asn253
Predicted molecular weight
30.98 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q15404
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
RSP-1, Rsu-1, RSP1, Ras suppressor protein 1, RSU1
Note
For research use only.
PINCH-1 promotes Bcl-2-dependent survival signalling and inhibits JNK-mediated apoptosis in the primitive endoderm., PMID:22946061
Promyelocytic leukemia (PML) protein plays important roles in regulating cell adhesion, morphology, proliferation and migration., PMID:23555679
Interactions by 2D Gel Electrophoresis Overlap (iGEO): a novel high fidelity approach to identify constituents of protein complexes., PMID:23663728
Rsu1 contributes to regulation of cell adhesion and spreading by PINCH1-dependent and - independent mechanisms., PMID:23765260
Role of PINCH and its partner tumor suppressor Rsu-1 in regulating liver size and tumorigenesis., PMID:24058607
Dissecting integrin-dependent regulation of neural stem cell proliferation in the adult brain., PMID:24719101
Rsu1 contributes to cell adhesion and spreading in MCF10A cells via effects on P38 map kinase signaling., PMID:25482629
Ras suppressor-1 promotes apoptosis in breast cancer cells by inhibiting PINCH-1 and activating p53-upregulated-modulator of apoptosis (PUMA); verification from metastatic breast cancer human samples., PMID:25647720
Elimination of Ras Suppressor-1 from hepatocellular carcinoma cells hinders their in vitro metastatic properties., PMID:25750304
Rsu1 regulates ethanol consumption in Drosophila and humans., PMID:26170296
Definition of a consensus integrin adhesome and its dynamics during adhesion complex assembly and disassembly., PMID:26479319
Preventing Illegitimate Extrasynaptic Acetylcholine Receptor Clustering Requires the RSU-1 Protein., PMID:27307240
Ras Suppressor-1 (RSU-1) in Cancer Cell Metastasis: Friend or Foe?, PMID:29604901
Suppression of microRNA-629 enhances sensitivity of cervical cancer cells to 1'S-1'-acetoxychavicol acetate via regulating RSU1., PMID:28356756
Identification of Ras suppressor-1 (RSU-1) as a potential breast cancer metastasis biomarker using a three-dimensional in vitro approach., PMID:28423706
MicroRNA-409-5p is upregulated in breast cancer and its downregulation inhibits cancer development through downstream target of RSU1., PMID:28459205
Chromatin Immunoprecipitation and DNA Sequencing Identified a LIMS1/ILK Pathway Regulated by LMO1 in Neuroblastoma., PMID:29695398
Novel functions for integrin-associated proteins revealed by analysis of myofibril attachment in Drosophila., PMID:30028294
A Four-gene Decision Tree Signature Classification of Triple-negative Breast Cancer: Implications for Targeted Therapeutics., PMID:30305342
Cancer biomarkers in atherosclerotic plaque: Evidenced from structural and proteomic analyses., PMID:30616890
Inhibition of Breast Cancer Cell Invasion by Ras Suppressor-1 (RSU-1) Silencing Is Reversed by Growth Differentiation Factor-15 (GDF-15)., PMID:30621163
Rsu1-dependent control of PTEN expression is regulated via ATF2 and cJun., PMID:30680530
Ras suppressor-1 (RSU-1) promotes cell invasion in aggressive glioma cells and inhibits it in non-aggressive cells through STAT6 phospho-regulation., PMID:31123330
Depletion of Ras Suppressor-1 (RSU-1) promotes cell invasion of breast cancer cells through a compensatory upregulation of a truncated isoform., PMID:31296919
Coordinated Expression of Ras Suppressor 1 (RSU-1) and Growth Differentiation Factor 15 (GDF15) Affects Glioma Cell Invasion., PMID:31412547
Altered Actin Filament Dynamics in the Drosophila Mushroom Bodies Lead to Fast Acquisition of Alcohol Consumption Preference., PMID:31558618
Silencing of Growth Differentiation Factor-15 Promotes Breast Cancer Cell Invasion by Down-regulating Focal Adhesion Genes., PMID:32132034
RSU-1 Maintains Integrity of Caenorhabditis elegans Vulval Muscles by Regulating α-Actinin., PMID:32461202
Ras Suppressor-1 (RSU1) in Cancer Cell Metastasis: A Tale of a Tumor Suppressor., PMID:32517326
Integrin-linked kinase (ILK) regulates KRAS, IPP complex and Ras suppressor-1 (RSU1) promoting lung adenocarcinoma progression and poor survival., PMID:32592097
MicroRNA-Dependent Targeting of RSU1 and the IPP Adhesion Complex Regulates the PTEN/PI3K/AKT Signaling Pathway in Breast Cancer Cell Lines., PMID:32751711
Novel role of circRSU1 in the progression of osteoarthritis by adjusting oxidative stress., PMID:33408787
Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics., PMID:33587032
RSU-1 interaction with prohibitin-2 links cell-extracellular matrix detachment to downregulation of ERK signaling., PMID:33853759
Identification of skin aging biomarkers correlated with the biomechanical properties., PMID:33891336
Molecular basis for Ras suppressor-1 binding to PINCH-1 in focal adhesion assembly., PMID:33891945
Genes and Pathways Affecting Sheep Productivity Traits: Genetic Parameters, Genome-Wide Association Mapping, and Pathway Enrichment Analysis., PMID:34394196
Circulating Exosome Involves in the Pathogenesis of Autoimmune Thyroid Diseases Through Immunomodulatory Proteins., PMID:34867951
Focal adhesion proteins in hepatocellular carcinoma: RSU1 a novel tumour suppressor with prognostic significance., PMID:35642986
Ras suppressor-1 (RSU1) exerts a tumor suppressive role with prognostic significance in lung adenocarcinoma., PMID:35729367
Bone Marrow Mesenchymal Stem Cells Derived from Juvenile Macaques Reversed the Serum Protein Expression Profile in Aged Macaques., PMID:35996242
Ras suppressor 1 long form (RSU1L) silencing promotes apoptosis in invasive breast cancer cells., PMID:36375714
In silico analysis of genomic landscape of SARS-CoV-2 and its variant of concerns (Delta and Omicron) reveals changes in the coding potential of miRNAs and their target genes., PMID:36470485
Proteomic profiling of circulating plasma exosomes reveals novel biomarkers of Alzheimer's disease., PMID:36471423
Circular RNA RSU1 promotes retinal vascular dysfunction by regulating miR-345-3p/TAZ., PMID:37443201
Comprehensive analysis of cell-extracellular matrix protein Ras suppressor-1 in function and prognosis of gastrointestinal cancers., PMID:37771863
CircRSU1 alleviates LPS-induced human pulmonary microvascular endothelial cell injury by targeting miR-1224-5p/ITGA5 axis., PMID:38312030
Potential Protein Signatures for Recurrence Prediction of Ischemic Stroke., PMID:38420847
RSU-1 regulates the integrity of dense bodies in muscle cells of aging Caenorhabditis elegans., PMID:38784006
New findings on the genetic basis of feathered legs in chickens: association of CUBN gene mutations with feathered-leg phenotype., PMID:39187978
For research use only. Not for human or drug use.
