Catalog No.
YHE91001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly1357-Glu1667
Predicted molecular weight
37.31 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P52179
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MYOM1, Myomesin family member 1, 190 kDa titin-associated protein, 190 kDa connectin-associated protein, Myomesin-1
Note
For research use only.
Skelemins: cytoskeletal proteins located at the periphery of M-discs in mammalian striated muscle., PMID:3553209
The globular head domain of titin extends into the center of the sarcomeric M band. cDNA cloning, epitope mapping and immunoelectron microscopy of two titin-associated proteins., PMID:7505783
Skelemin, a cytoskeletal M-disc periphery protein, contains motifs of adhesion/recognition and intermediate filament proteins., PMID:8408035
Assignment of the human gene for the sarcomeric M-band protein myomesin (MYOM1) to 18p11.31-p11.32., PMID:9806852
Identification of an interaction between the m-band protein skelemin and beta-integrin subunits. Colocalization of a skelemin-like protein with beta1- and beta3-integrins in non-muscle cells., PMID:9857037
M band proteins myomesin and skelemin are encoded by the same gene: analysis of its organization and expression., PMID:10036188
Dynamic modulation of cytoskeletal proteins linking integrins to signaling complexes in spreading cells. Role of skelemin in initial integrin-induced spreading., PMID:11382766
Postnatal suppression of myomesin, muscle creatine kinase and the M-line in rat extraocular muscle., PMID:12878677
Isolation and characterization of 190K protein from aorta smooth muscle., PMID:15098669
Genomic structure and organization of the high grade Myopia-2 locus (MYP2) critical region: mutation screening of 9 positional candidate genes., PMID:15723005
Unbalanced whole arm translocation resulting in loss of 18p in dystonia., PMID:16541453
Identification and characterization of layer-specific differences in extraocular muscle m-bands., PMID:17325154
Blood cell gene expression profiling in subjects with aggressive periodontitis and chronic arthritis., PMID:18315430
Nuclear localization of Myomesin-1: possible functions., PMID:18521710
Serum response factor orchestrates nascent sarcomerogenesis and silences the biomineralization gene program in the heart., PMID:19004760
Adhesion-induced unclasping of cytoplasmic tails of integrin alpha(IIb)beta3., PMID:19117493
Mouse chromosome 17 candidate modifier genes for thrombosis., PMID:20700597
Myomasp/LRRC39, a heart- and muscle-specific protein, is a novel component of the sarcomeric M-band and is involved in stretch sensing., PMID:20847312
Alternative splicing of myomesin 1 gene is aberrantly regulated in myotonic dystrophy type 1., PMID:21794030
Myofibrillogenesis regulator 1 induces hypertrophy by promoting sarcomere organization in neonatal rat cardiomyocytes., PMID:22418241
Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach., PMID:23236287
Identification of an interstitial 18p11.32-p11.31 duplication including the EMILIN2 gene in a family with porokeratosis of Mibelli., PMID:23593459
Skelemin association with αIIbβ3 integrin: a structural model., PMID:25224262
Loss of muscleblind-like 1 results in cardiac pathology and persistence of embryonic splice isoforms., PMID:25761764
Effective population size, extended linkage disequilibrium and signatures of selection in the rare dog breed lundehund., PMID:25860808
OBSCN Mutations Associated with Dilated Cardiomyopathy and Haploinsufficiency., PMID:26406308
Binding of Myomesin to Obscurin-Like-1 at the Muscle M-Band Provides a Strategy for Isoform-Specific Mechanical Protection., PMID:27989621
Dissection of Z-disc myopalladin gene network involved in the development of restrictive cardiomyopathy using system genetics approach., PMID:28515850
Comparative analysis on genome-wide DNA methylation in longissimus dorsi muscle between Small Tailed Han and Dorper×Small Tailed Han crossbred sheep., PMID:28728367
The effect of high fat diet on daily rhythm of the core clock genes and muscle functional genes in the skeletal muscle of Chinese soft-shelled turtle (Trionyx sinensis)., PMID:28729066
Cardiomyocytes have mosaic patterns of protein expression., PMID:29677652
Effects of dietary amino acid supplementation on measures of whole-body and muscle protein metabolism in aged horses., PMID:30284316
Mutant myocilin impacts sarcomere ultrastructure in mouse gastrocnemius muscle., PMID:30395621
Hydrogen sulphide ameliorating skeletal muscle atrophy in db/db mice via Muscle RING finger 1 S-sulfhydration., PMID:32633463
Knockout of MYOM1 in human cardiomyocytes leads to myocardial atrophy via impairing calcium homeostasis., PMID:33452765
The miR-223/nuclear factor I-A axis regulates inflammation and cellular functions in intestinal tissues with necrotizing enterocolitis., PMID:33932136
Splicing factor Srsf5 deletion disrupts alternative splicing and causes noncompaction of ventricular myocardium., PMID:34622152
Gill and Liver Transcript Expression Changes Associated With Gill Damage in Atlantic Salmon (Salmo salar)., PMID:35418993
MiR-135a is highly expressed and aggravates inflammatory response in sepsis by targeting MYOM1., PMID:35977075
Pathogenesis of Cardiomyopathy Caused by Variants in ALPK3, an Essential Pseudokinase in the Cardiomyocyte Nucleus and Sarcomere., PMID:36321451
Automated SSHHPS Analysis Predicts a Potential Host Protein Target Common to Several Neuroinvasive (+)ssRNA Viruses., PMID:36851756
Membrane tension-mediated stiff and soft tumor subtypes closely associated with prognosis for prostate cancer patients., PMID:37179366
Proteomic analysis of the serum in dogs with pulmonary hypertension secondary to myxomatous mitral valve disease: the preliminary study., PMID:38596466
Identification of the cytoplasmic DNA-Sensing cGAS-STING pathway-mediated gene signatures and molecular subtypes in prostate cancer., PMID:38877472
For research use only. Not for human or drug use.
