Catalog No.
YHK52201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala37-Gly483
Predicted molecular weight
52.30 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9HBX8
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% SKL, 1mM EDTA, 5% Trehalose, 2% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Leucine-rich repeat-containing G-protein coupled receptor 6, LGR6
Note
For research use only.
Mechanical tension mobilizes Lgr6+ epidermal stem cells to drive skin growth., PMID:35476447
Maresin 1 Alleviates Diabetic Kidney Disease via LGR6-Mediated cAMP-SOD2-ROS Pathway., PMID:35498124
Impact of defensins-containing body cream on skin composition., PMID:35621235
LGR6 Acts as an Oncogene and Induces Proliferation and Migration of Gastric Cancer Cells., PMID:35695661
Maresin 1 intervention reverses experimental pulmonary arterial hypertension in mice., PMID:35764296
Maresin-1 and its receptors RORα/LGR6 as potential therapeutic target for respiratory diseases., PMID:35781060
LGR6-dependent conditional inactivation of E-cadherin and p53 leads to invasive skin and mammary carcinomas in mice., PMID:36371908
The Maresin 1-LGR6 axis decreases respiratory syncytial virus-induced lung inflammation., PMID:36595677
Resolution of post-lung transplant ischemia-reperfusion injury is modulated via Resolvin D1-FPR2 and Maresin 1-LGR6 signaling., PMID:36628837
High expression of LGR6 is a poor prognostic factor in esophageal carcinoma., PMID:36701848
Wnt-associated adult stem cell marker Lgr6 is required for osteogenesis and fracture healing., PMID:36708855
Analysis of dog breed diversity using a composite selection index., PMID:36717599
Explainable artificial intelligence model for identifying COVID-19 gene biomarkers., PMID:36738712
Wound healing by transplantation of mesenchymal stromal cells loaded on polyethylene terephthalate scaffold: Implications for skin injury treatment., PMID:36801131
Exploiting the Receptor-Binding Domains of R-Spondin 1 to Target Leucine-Rich Repeat-Containin G-Coupled Protein Receptor 5-Expressing Stem Cells in Ovarian Cancer., PMID:36849411
Comprehensive analysis of cuproptosis-related immune biomarker signature to enhance prognostic accuracy in gastric cancer., PMID:37036489
Maresin1: A multifunctional regulator in inflammatory bone diseases., PMID:37192551
All-Trans Retinoic Acid-Responsive LGR6 Is Transiently Expressed during Myogenic Differentiation and Is Required for Myoblast Differentiation and Fusion., PMID:37240382
Maresin-1 protects against pulmonary arterial hypertension by improving mitochondrial homeostasis through ALXR/HSP90α axis., PMID:37244057
Maresin 1 activates brown adipose tissue and promotes browning of white adipose tissue in mice., PMID:37271337
Sex differences in specialized pro-resolving lipid mediators and their receptors in abdominal aortic aneurysms., PMID:37292185
LITTIP/Lgr6/HnRNPK complex regulates cementogenesis via Wnt signaling., PMID:37558690
Spatiotemporal expression patterns of R-spondins and their receptors, Lgrs, in the developing mouse telencephalon., PMID:37651925
A Cell Surface-Binding Antibody Atlas Nominates a MUC18-Directed Antibody-Drug Conjugate for Targeting Melanoma., PMID:37668527
Clinical Trial of Alpha and Beta Defensin Skin Care Regimen for Improvement of Periocular Wrinkles., PMID:37683059
WNT enhancing signals in pancreatic cancer are transmitted by LGR6., PMID:37770230
DNA methylation and expression of LGR6 gene in ankylosing spondylitis: A case-control study., PMID:37802707
Antiaging Effects of Topical Defensins., PMID:37806687
The oncogenic role of LGR6 overexpression induced by aberrant Wnt/β-catenin signaling in lung cancer., PMID:38014454
Flow induces common and specific transcriptional changes in renal tubular epithelial cells involving the PI3K pathway., PMID:38050412
Maresin 1 Activates LGR6 to Alleviate Neuroinflammation via the CREB/JMJD3/IRF4 Pathway in a Rat Model of Subarachnoid Hemorrhage., PMID:38340785
Alterations in epidermal stem cells within the pilosebaceous unit in atrophic acne scars., PMID:38419202
Maresin-1 ameliorates hypertensive vascular remodeling through its receptor LGR6., PMID:38463394
Construction of an immune-related gene signature for overall survival prediction and immune infiltration in gastric cancer., PMID:38577455
The CC2D2B is a novel genetic modifier of the clinical phenotype in patients with hereditary angioedema due to C1 inhibitor deficiency., PMID:38679185
An LGR6 frameshift variant abrogates receptor expression on select leukocyte subsets and is associated with viral infections., PMID:38718314
Lgr6-expressing functional nail stem-like cells differentiated from human-induced pluripotent stem cells., PMID:38743670
Identification of a G-protein coupled receptor-related gene signature through bioinformatics analysis to construct a risk model for ovarian cancer prognosis., PMID:38897150
Signaling pathways associated with Lgr6 to regulate osteogenesis., PMID:39033993
Cardiomyocyte LGR6 alleviates ferroptosis in diabetic cardiomyopathy via regulating mitochondrial biogenesis., PMID:39038735
Varied roles for LGR6 in the immune response., PMID:39052274
The integrated molecular and histological analysis defines subtypes of esophageal squamous cell carcinoma., PMID:39419971
Evaluation of Osteogenic Phenotype in Postmenopausal Women Receiving Anabolic and Antiresorptive Osteoporosis Therapies., PMID:39445778
LGR6 protects against myocardial ischemia-reperfusion injury via suppressing necroptosis., PMID:39471639
Single-Cell RNA Sequencing Reveals LEF1-Driven Wnt Pathway Activation as a Shared Oncogenic Program in Hepatoblastoma and Medulloblastoma., PMID:39851951
Role of Leucine-Rich Repeat-Containing G-Protein-Coupled Receptors 4-6 (LGR4-6) in the Ovary and Other Female Reproductive Organs: A Literature Review., PMID:39874091
Maresin 1-LGR6 axis mitigates inflammation and posttraumatic osteoarthritis after transection of the anterior cruciate ligament in mice., PMID:40139646
Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6 Ameliorates Pressure Overload-Induced Cardiac Hypertrophy by Regulating Cardiomyocyte Metabolic Reprogramming., PMID:40211903
[Effect of acupuncture on early embryos in poor ovarian response mice based on transcriptome sequencing]., PMID:40229158
LGR6 modulates intervertebral disc degeneration through regulation of macrophage efferocytosis., PMID:40281518
For research use only. Not for human or drug use.
