Catalog No.
PHC32301
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human MMP2 (Tyr110-Cys660).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
72 kDa gelatinase,Matrix metalloproteinase-2,Gelatinase A,TBE-1,MMP2,CLG4A,72 kDa type IV collagenase,MMP-2
Purification
Purified by antigen affinity column.
Accession
P08253
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
[A novel fully human LAG-3 monoclonal antibody LBL-007 combined with PD-1 antibody inhibits proliferation, migration and invasion of tumor cells via blocking NF-κB pathway]., PMID:40415618
Investigating Anti-Tumor Effects of Irisin in Cervical Cancer Cells: Cell Viability, Migration, and Tumor-Associated Macrophage Polarization., PMID:40415369
Tumor microenvironment modulation by SERPINE1 increases radioimmunotherapy in murine model of gastric cancer., PMID:40355586
BAP1-mediated ubiquitination inhibition and CAS6/AXL signaling activation in bladder cancer progression., PMID:40330545
Time to focus again on matrix metalloproteinases? Results of complex network analysis involving the pathophysiology of HER2-positive breast cancer., PMID:40259907
Protease-activated anti-Lewis Y antibody enhances selectivity and safety of glycan-targeting cancer therapy., PMID:40246093
The potential of miR-29 in modulating tumor angiogenesis: a comprehensive review., PMID:40189720
Early effects of anti-TNFα antibodies in horses with osteoarthritis., PMID:39956345
CD47-blocking antibody interferes with neutrophil extracellular traps formation after spinal cord injury to reduce spinal cord edema., PMID:39951937
Expression of MMP-2, MMP-9 and TIMP-2 in pituitary tumors and their relationship with cavernous sinus invasion., PMID:39810846
Development of a peptide-based tumor-activated checkpoint inhibitor for cancer immunotherapy., PMID:39716541
Exploring the Interplay Between Senescent Osteocytes and Bone Remodeling in Young Rodents., PMID:39583064
Protein Biomarkers of Adverse Clinical Features and Events in Sarcomeric Hypertrophic Cardiomyopathy., PMID:39498543
Human adipose-derived stem cells promote migration of papillary thyroid cancer cell via leptin pathway., PMID:39450935
Cancer-Associated Fibroblast Proteins as Potential Targets against Colorectal Cancers., PMID:39335130
Turmeric extract alleviates airway inflammation via oxidative stress-driven MAPKs/MMPs pathway., PMID:39216235
Targeted therapies in HER2-positive breast cancer with receptor-redirected Arazyme-linker-Herceptin as a novel fusion protein., PMID:39122876
Engineering a tumor-selective prodrug T-cell engager bispecific antibody for safer immunotherapy., PMID:38962811
Bidirectional Two-Sample Mendelian Randomization Study of Immunoglobulin G N-Glycosylation and Senescence-Associated Secretory Phenotype., PMID:38928043
Complement regulatory protein CD46 promotes bladder cancer metastasis through activation of MMP9., PMID:38847230
Correlation between Matrix Metalloproteinase Presence and Caries Surface Appearance., PMID:38815561
PRG4 represses the genesis and metastasis of osteosarcoma by inhibiting PDL1 expression., PMID:38781792
Intelligent nanovesicle for remodeling tumor microenvironment and circulating tumor chemoimmunotherapy amplification., PMID:38755645
Cytokine CCL9 Mediates Oncogenic KRAS-Induced Pancreatic Acinar-to-Ductal Metaplasia by Promoting Reactive Oxygen Species and Metalloproteinases., PMID:38731942
Multiplexed Opto-Microfluidic Biosensing: Advanced Platform for Prostate Cancer Detection., PMID:38683677
Dual-Responsive Nanomedicine Activates Programmed Antitumor Immunity through Targeting Lymphatic System., PMID:38639726
Inhibition of PD-L1 expression in non-small cell lung cancer may reduce vasculogenic mimicry formation by inhibiting the epithelial mesenchymal transformation process., PMID:38508327
Machine learning application identifies plasma markers for proteinuria in metastatic colorectal cancer patients treated with Bevacizumab., PMID:38402561
CETP-derived Peptide Seq-1, the Key Component of HB-ATV-8 Vaccine Prevents Stress Responses, and Promotes Downregulation of Pro-Fibrotic Genes in Hepatocytes and Stellate Cells., PMID:38301446
MMP-2-mediated Scube2 degradation promotes blood-brain barrier disruption by blocking the interaction between astrocytes and endothelial cells via inhibiting Sonic hedgehog pathway during early cerebral ischemia., PMID:38148633
The activity, distribution, and colocalization of cathepsin K and matrix metalloproteases in intact and eroded dentin., PMID:38114764
Elevated Serum Gastrin Is Associated with Melanoma Progression: Putative Role in Increased Migration and Invasion of Melanoma Cells., PMID:38069171
Disruption of CADM1-dependent cell-cell adhesion in human oral squamous cell carcinoma cells results in tumor progression, possibly through an increase of MMP-2 and MMP-9 expression., PMID:38030062
Neurotransmission, Vasculogenesis, and Osteogenesis Activities are Altered in the Aging Temporomandibular Joint of the Senescence-Accelerated Prone 8 Mouse Model., PMID:37832598
Regulatory T-cell deficiency leads to features of autoimmune liver disease overlap syndrome in scurfy mice., PMID:37818371
MT1-MMP as a Key Regulator of Metastasis., PMID:37681919
Ganoderma lucidum polysaccharide peptide (GLPP) attenuates rheumatic arthritis in rats through inactivating NF-κB and MAPK signaling pathways., PMID:37586160
Impact of dual neutralization of TNF-α and IL-1β along with Gentamicin treatment on the functions of blood and splenic neutrophils and its role on improvement of S. aureus induced septic arthritis., PMID:37572502
Vasorin promotes proliferation and migration via STAT3 signaling and acts as a promising therapeutic target of hepatocellular carcinoma., PMID:37454705
Chlorotoxin binds to both matrix metalloproteinase 2 and neuropilin 1., PMID:37394009
2D vanadium disulfide nanosheets assisted ultrasensitive, rapid, and label-free electrochemical quantification of cancer biomarker (MMP-2)., PMID:37311440
Immunohistochemical study of MMP-2, MMP-9, EGFR and IL-8 in decidual and trophoblastic specimens of recurrent pregnancy loss cases., PMID:37258409
An optical fiber-based point-of-care test for periodontal MMP-8 detection: A proof of concept., PMID:37201775
Histopathological, biochemical and molecular studies on a model of systemic autoimmune disease induced by sodium silicate in non-genetically prone rats., PMID:37100362
Engineering MMP-2 Activated Nanoparticles Carrying B7-H3 Bispecific Antibodies for Ferroptosis-Enhanced Glioblastoma Immunotherapy., PMID:37097811
A Bioinformatics Assessment Indicating Better Outcomes With Breast Cancer Resident, Immunoglobulin CDR3-MMP2 Binding., PMID:37093687
Constructed Tumor-Targeted and MMP-2 Biocleavable Antibody Conjugated Silica Nanoparticles for Efficient Cancer Therapy., PMID:37065049
Multi-Targeting Anticancer Activity of a New 4-Thiazolidinone Derivative with Anti-HER2 Antibodies in Human AGS Gastric Cancer Cells., PMID:37047765
Rac2 regulates immune complex-mediated granule polarization and exocytosis in neutrophils., PMID:37017007
Reprogramming Hypoxic Tumor-Associated Macrophages by Nanoglycoclusters for Boosted Cancer Immunotherapy., PMID:36971342
For research use only. Not for human or drug use.
