Catalog No.
YHG04101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Arg271
Predicted molecular weight
32.02 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q05193
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DNM1, DNM, Dynamin-1
Note
For research use only.
Screening of candidate genes associated with high titer production of oncolytic measles virus based on systems biology approach., PMID:35477822
The acyl-CoA-binding protein Acb1 regulates mitochondria, lipid droplets, and cell proliferation., PMID:35658118
Thymol and trans-cinnamaldehyde induce apoptosis through a metacaspase-dependent mitochondrial pathway in food-spoilage yeast Zygosaccharomyces rouxii., PMID:35986680
Continuous 17α-ethinylestradiol exposure impairs the sperm quality of marine medaka (Oryzias melastigma)., PMID:36084614
Eisosome protein Pil1 regulates mitochondrial morphology, mitophagy, and cell death in Saccharomyces cerevisiae., PMID:36162502
Reduced dynamin-1 levels in neurons lacking MUNC18-1., PMID:36245272
The contribution of endocytosis to sensitization of nociceptors and synaptic transmission in nociceptive circuits., PMID:36378744
A recurrent de novo splice site variant involving DNM1 exon 10a causes developmental and epileptic encephalopathy through a dominant-negative mechanism., PMID:36413998
Clinical, Radiological, and Genetic Characterization of a Patient with a Novel Homoallelic Loss-of-Function Variant in DNM1., PMID:36553519
The dynamin-related protein Vps1 and the peroxisomal membrane protein Pex27 function together during peroxisome fission., PMID:36825558
Zebrafish dnm1a gene plays a role in the formation of axons and synapses in the nervous tissue., PMID:37031448
An intermembrane space protein facilitates completion of mitochondrial division in yeast., PMID:37034761
A deep intronic variant in DNM1 in a patient with developmental and epileptic encephalopathy creates a splice acceptor site and affects only transcript variants including exon 10a., PMID:37039969
Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1., PMID:37132416
The mitochondrial intermembrane space protein mitofissin drives mitochondrial fission required for mitophagy., PMID:37192628
Dynamins in human diseases: differential requirement of dynamin activity in distinct tissues., PMID:37230036
Differential Efficacy of Small Molecules Dynasore and Mdivi-1 for the Treatment of Dry Eye Epitheliopathy or as a Countermeasure for Nitrogen Mustard Exposure of the Ocular Surface., PMID:37442618
Completion of mitochondrial division requires the intermembrane space protein Mdi1/Atg44., PMID:37540145
The AAA-ATPase Yta4/ATAD1 interacts with the mitochondrial divisome to inhibit mitochondrial fission., PMID:37590302
Reversal of cell, circuit and seizure phenotypes in a mouse model of DNM1 epileptic encephalopathy., PMID:37648685
Targeting of insulin receptor endocytosis as a treatment to insulin resistance., PMID:37788593
Insights into the role of the conserved GTPase domain residues T62 and S277 in yeast Dnm1., PMID:37838106
Truncated DNM1 variant underlines developmental delay and epileptic encephalopathy., PMID:37900685
Abnormal axonal development and severe epileptic phenotype in Dynamin-1 (DNM1) encephalopathy., PMID:38009673
Comparing multifunctional viral and eukaryotic proteins for generating scission necks in membranes., PMID:38260291
A quantitative ultrastructural timeline of nuclear autophagy reveals a role for dynamin-like protein 1 at the nuclear envelope., PMID:38405892
Chemical inhibition of phosphatidylcholine biogenesis reveals its role in mitochondrial division., PMID:38420588
Proteomics-based Model for Predicting the Risk of Brain Metastasis in Patients with Resected Lung Adenocarcinoma carrying the EGFR Mutation., PMID:38464823
The Structural and Functional Integrity of Rod Photoreceptor Ribbon Synapses Depends on Redundant Actions of Dynamins 1 and 3., PMID:38641407
Hansenula polymorpha cells lacking the ER-localized peroxins Pex23 or Pex29 show defects in mitochondrial function and morphology., PMID:38682287
LINC08148 promotes the caveola-mediated endocytosis of Zika virus through upregulating transcription of Src., PMID:38742902
Atg44/Mdi1/mitofissin facilitates Dnm1-mediated mitochondrial fission., PMID:38818923
Comparing Multifunctional Viral and Eukaryotic Proteins for Generating Scission Necks in Membranes., PMID:38838261
Effective knockdown-replace gene therapy in a novel mouse model of DNM1 developmental and epileptic encephalopathy., PMID:39127888
Endocytosis restricts dendrite branching via removing ectopically localized branching ligands., PMID:39511227
Dynamin-1 is a potential mediator in cancer-related cognitive impairment., PMID:39516074
Yeast Dnm1G178R causes altered organelle dynamics and sheds light on the human DRP1G149R disease mechanism., PMID:39788359
AP2M1 as the potential biomarker for prediction of the response of atopic dermatitis to Dupilumab therapy: Multi-omics analysis and evidence., PMID:39818381
A quantitative ultrastructural timeline of nuclear autophagy reveals a role for dynamin-like protein 1 at the nuclear envelope., PMID:39920277
Expanding the phenotypic spectrum of DNM1-related disorders: novel GTPase domain variants and their diverse neurological outcomes., PMID:39954101
Reversal of metformin's anti-proliferative effect in fission yeast efr3 and dnm1 (DRP1) mutants with elongated mitochondria., PMID:39991135
Cancer ATF4-mediated CD58 endocytosis impairs anti-tumor immunity and immunotherapy., PMID:40001116
Global DNA Methylation and DNA Methyltransferase Status Among Cigarette Smokers in Saudi., PMID:40003580
Exploring the underlying molecular connections: a bioinformatics approach to link melanoma and Parkinson's disease., PMID:40066251
Breaking the Synaptic Vesicle Cycle: Mechanistic Insights into Presynaptic Dysfunctions in Epilepsy., PMID:40190794
High glucose induces senescence in synovial mesenchymal stem cells through mitochondrial dysfunction., PMID:40234847
Active control of mitochondrial network morphology by metabolism-driven redox state., PMID:40244668
OTX2 expression contributes progression of gastric cancer in young adults., PMID:40341176
Endophilin A1 and synaptojanin 1-dependent endocytosis of synaptic vesicles in nociceptive spinal circuits maintains postoperative and cancer pain., PMID:40488273
For research use only. Not for human or drug use.
