Catalog No.
YHH29601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala41-Asn306
Predicted molecular weight
32.48 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q16566
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CAMK, CaMK IV, CaM kinase-GR, CAMKIV, Calcium/calmodulin-dependent protein kinase type IV, CAMK-GR, CAMK4
Note
For research use only.
Multiomics Identification of Potential Targets for Alzheimer Disease and Antrocin as a Therapeutic Candidate., PMID:34683848
Calcium/calmodulin-dependent protein kinase IV regulates vascular autophagy and insulin signaling through Akt/mTOR/CREB pathway in ob/ob mice., PMID:34741274
Atractylodin inhibits fructose-induced human podocyte hypermotility via anti-oxidant to down-regulate TRPC6/p-CaMK4 signaling., PMID:34780752
Resveratrol ameliorates polycystic ovary syndrome via transzonal projections within oocyte-granulosa cell communication., PMID:34976213
A CD8+ T Cell-Related Genes Expression Signature Predicts Prognosis and the Efficacy of Immunotherapy in Breast Cancer., PMID:35088220
Anti-phospholipase A2 receptor antibodies directly induced podocyte damage in vitro., PMID:35333675
Human forebrain organoids reveal connections between valproic acid exposure and autism risk., PMID:35351869
Tyrosine Phosphorylation Profiling Revealed the Signaling Network Characteristics of CAMKK2 in Gastric Adenocarcinoma., PMID:35646067
CaMK4 Promotes Acute Lung Injury Through NLRP3 Inflammasome Activation in Type II Alveolar Epithelial Cell., PMID:35734175
Inhibition of calcium/calmodulin-dependent protein kinase IV in arthritis: dual effect on Th17 cell activation and osteoclastogenesis., PMID:35781320
Calcium/calmodulin-dependent protein kinase IV promotes imiquimod-induced psoriatic inflammation via macrophages and keratinocytes in mice., PMID:35869084
Weighted Gene Coexpression Network Analysis Identifies Crucial Genes Involved in Coronary Atherosclerotic Heart Disease., PMID:35958279
CaMK4 overexpression in polycystic kidney disease promotes mTOR-mediated cell proliferation., PMID:36002021
Combination of panax ginseng and ginkgo biloba extracts attenuate cerebral ischemia injury with modulation of NLRP3 inflammasome and CAMK4/CREB pathway., PMID:36091745
Diet X Gene Interactions Control Femoral Bone Adaptation to Low Dietary Calcium., PMID:36111202
Transcriptomics of circulating neutrophils in dairy cows with subclinical hypocalcemia., PMID:36176696
Identification of differentially expressed genes induced by aberrant methylation in acute myeloid leukemia using integrated bioinformatics analyses., PMID:36238356
Genes Whose Gain or Loss of Function Changes Type 1, 2A, 2X, or 2B Muscle Fibre Proportions in Mice-A Systematic Review., PMID:36361732
Phosphofructokinase P fine-tunes T regulatory cell metabolism, function, and stability in systemic autoimmunity., PMID:36449620
CaMK4 expression on effector memory T cells is associated with organ damage in systemic lupus erythematosus: A case report., PMID:36632870
Full-Length Transcriptome of the Great Himalayan Leaf-Nosed Bats (Hipposideros armiger) Optimized Genome Annotation and Revealed the Expression of Novel Genes., PMID:36902366
Polycyclic aromatic hydrocarbons exposure and plasma lncRNA signature: A profile and functional analysis., PMID:36934921
Single-cell analysis highlights a population of Th17-polarized CD4+ naïve T cells showing IL6/JAK3/STAT3 activation in pediatric severe aplastic anemia., PMID:37001436
Identification of CaMK4 as a sex-difference-related gene in knee osteoarthritis., PMID:37007557
Fasudil compensates podocyte injury via CaMK4/Rho GTPases signal and actin cytoskeleton-dependent activation of YAP in MRL/lpr mice., PMID:37094544
Hypericin Ameliorates Depression-like Behaviors via Neurotrophin Signaling Pathway Mediating m6A Epitranscriptome Modification., PMID:37175269
Expression of chronic pain genes in apical periodontitis tissues., PMID:37183358
Multiple calcium signaling genes play a role in the circadian period of Neurospora crassa., PMID:37193664
Effects of melatonin on a d-galactose-induced male reproductive aging mouse model., PMID:37224707
Calcium/calmodulin dependent protein kinase IV in trophoblast cells under insulin resistance: functional and metabolomic analyses., PMID:37386367
Immune landscape and prognostic gene signatures in gastric cancer: implications for cachexia and clinical outcomes., PMID:38035067
The mechanisms underlying alcohol-induced decreased splenic size: A network meta-analysis study., PMID:38059389
CaMK4 controls follicular helper T cell expansion and function during normal and autoimmune T-dependent B cell responses., PMID:38287012
Nuclear Binding Protein 2/Nesfatin-1 Affects Trophoblast Cell Fusion during Placental Development via the EGFR-PLCG1-CAMK4 Pathway., PMID:38339201
Understanding the pathogenic significance of altered calcium-calmodulin signaling in T cells in autoimmune diseases., PMID:38460894
The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3'-UTR and promoting Rag1 mRNA expression., PMID:38467629
Integrative Kinase Activity Profiling and Phosphoproteomics of rd10 Mouse Retina during cGMP-Dependent Retinal Degeneration., PMID:38542418
miR-129-5p inhibits anchorage-independent growth through silencing of ACTN1 and the ELK4/c-FOS axis in HPV-transformed keratinocytes., PMID:38566572
Investigation of the underlying mechanism of Buyang Huanwu decoction in ischemic stroke by integrating systems pharmacology-proteomics and in vivo experiments., PMID:38580032
CaMK4: Structure, physiological functions, and therapeutic potential., PMID:38615920
Effect of RNAi mediated silencing of DIB, JHE, and CAM on the diapause termination of Calliptamus italicus (Orthoptera: Acrididae) eggs., PMID:38984807
TIPRL Regulates Stemness and Survival in Lung Cancer Stem Cells through CaMKK2-CaMK4-CREB Feedback Loop Activation., PMID:39076120
PVT1 regulates hippocampal neuron apoptosis and inflammation in epilepsy by miR-206-3p-dependent regulation of CAMK4., PMID:39140685
Role of sodium-dependent vitamin C transporter 2 in human periodontal ligament fibroblasts., PMID:39225294
Convergence on CaMK4: A Key Modulator of Autism-Associated Signaling Pathways in Neurons., PMID:39442785
Guilu Erxian Jiao remodels dendritic spine morphology through activation of the hippocampal TRPC6-CaMKIV-CREB signaling pathway and suppresses fear memory generalization in rats with post-traumatic stress disorder., PMID:39681200
Calcium calmodulin kinase IV deficiency in podocytes prevents the development of lupus nephritis., PMID:39793862
TRPC6 suppresses liver fibrosis by inhibiting hepatic stellate cell activation via CaMK4-CREB pathway., PMID:39887689
Impaired CAMK4 Activity Limits Atherosclerosis and Reprograms Myelopoiesis., PMID:40336480
CaMK modulates sensory neural activity to control longevity and proteostasis., PMID:40359038
For research use only. Not for human or drug use.
