Catalog No.
YHM00501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly22-Pro304
Predicted molecular weight
34.92 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P30511
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Leukocyte antigen F, CDA12, MHC class I antigen F, HLA F antigen, HLA-F, HLAF, HLA class I histocompatibility antigen, alpha chain F, HLA-5.4
Note
For research use only.
Targeting HLA-F suppresses the proliferation of glioma cells via a reduction in hexokinase 2-dependent glycolysis., PMID:33867844
Immune-related genes and gene sets for predicting the response to anti-programmed death 1 therapy in patients with primary or metastatic non-small cell lung cancer., PMID:34084219
Differential transcriptional and functional properties of regulatory T cells in HIV-infected individuals on antiretroviral therapy and long-term non-progressors., PMID:34094548
Extended loci histocompatibility matching in HSCT-Going beyond classical HLA., PMID:34109752
Development of a Novel Prognostic Signature Based on Antigen Processing and Presentation in Patients with Breast Cancer., PMID:34257557
Transcriptome analysis of human dorsal striatum implicates attenuated canonical WNT signaling in neuroinflammation and in age-related impairment of striatal neurogenesis and synaptic plasticity., PMID:34275915
Allotype-Specific Glycosylation and Cellular Localization of Human Leukocyte Antigen Class I Proteins., PMID:34415762
KIR3DS1 directs NK cell-mediated protection against human adenovirus infections., PMID:34533978
A Genome-Wide CRISPR/Cas9-Based Screen Identifies Heparan Sulfate Proteoglycans as Ligands of Killer-Cell Immunoglobulin-Like Receptors., PMID:34917099
HLA-E and HLA-F Are Overexpressed in Glioblastoma and HLA-E Increased After Exposure to Ionizing Radiation., PMID:35181585
HLA Class Ib-receptor interactions during embryo implantation and early pregnancy., PMID:35234898
LncRNA HLA-F-AS1 attenuates the ovarian cancer development by targeting miR-21-3p/PEG3 axis., PMID:35276697
Epigenome-Wide DNA Methylation Profiling of Normal Mucosa Reveals HLA-F Hypermethylation as a Biomarker Candidate for Serrated Polyposis Syndrome., PMID:35447336
Integrated Analysis of Multiple Microarray Studies to Identify Core Gene-Expression Signatures Involved in Tubulointerstitial Injury in Diabetic Nephropathy., PMID:35592524
Long non-coding RNA HLA-F antisense RNA 1 inhibits the maturation of microRNA-613 in polycystic ovary syndrome to promote ovarian granulosa cell proliferation and inhibit cell apoptosis., PMID:35603775
Immunity at maternal-fetal interface: KIR/HLA (Allo)recognition., PMID:35610960
Endometrial HLA-F expression is influenced by genotypes and correlates differently with immune cell infiltration in IVF and recurrent implantation failure patients., PMID:35689445
Sib-pair subgroup familial type 1 diabetes mellitus in children in the state of Qatar., PMID:35802651
Human leukocyte antigens: the unique expression in trophoblasts and their crosstalk with local immune cells., PMID:35844794
Human leukocyte antigen HLA-C, HLA-G, HLA-F, and HLA-E placental profiles are altered in early severe preeclampsia and preterm birth with chorioamnionitis., PMID:35863458
Evolution and molecular interactions of major histocompatibility complex (MHC)-G, -E and -F genes., PMID:35925520
Sequence Variations Within HLA-G and HLA-F Genomic Segments at the Human Leukocyte Antigen Telomeric End Associated With Acute Graft-Versus-Host Disease in Unrelated Bone Marrow Transplantation., PMID:35935961
Mobilisation of HLA-F on the surface of bronchial epithelial cells and platelets in asthmatic patients., PMID:35988034
Advances in the study of HLA class Ib in maternal-fetal immune tolerance., PMID:36105800
Recombinant Human Proteoglycan 4 (rhPRG4) Downregulates TNFα-Stimulated NFκB Activity and FAT10 Expression in Human Corneal Epithelial Cells., PMID:36361504
Maternal SARS-CoV-2 exposure alters infant DNA methylation., PMID:36570792
Quantitative proteomics of differentiated primary bronchial epithelial cells from chronic obstructive pulmonary disease and control identifies potential novel host factors post-influenza A virus infection., PMID:36713229
Ubiquitin like protein FAT10 repressed cardiac fibrosis after myocardial ischemic via mediating degradation of Smad3 dependent on FAT10-proteasome system., PMID:36778114
FAT10 Silencing Prevents Liver Fibrosis through Regulating SIRT1 Expression in Hepatic Stellate Cells., PMID:37057207
Potential common molecular mechanisms between Sjögren syndrome and inclusion body myositis: a bioinformatic analysis and in vivo validation., PMID:37153570
HLA-F transcriptional and protein differential expression according to its genetic polymorphisms., PMID:37166140
Opposing impacts of HLA-G haplotypes PROMO-G010104-UTR-3 and PROMO-G010101b/c-UTR-4 on risk of recurrent implantation failure., PMID:37330336
Bioinformatic analysis of gene expression data reveals Src family protein tyrosine kinases as key players in androgenetic alopecia., PMID:37359019
The role of non-classical and chain-related human leukocyte antigen polymorphisms in laryngeal squamous cell carcinoma., PMID:37418079
HLA-F and LILRB1 Genetic Polymorphisms Associated with Alloimmunisation in Sickle Cell Disease., PMID:37686397
Association of human leukocyte antigen-G and -F with recurrent miscarriage and implantation failure: A systematic review and meta-analysis., PMID:38009058
Methods for Co-culture of Primary Human Extravillous Trophoblast Cells and Uterine Natural Killer Cells., PMID:38019402
Multi-omics reveals the switch role of abnormal methylation in the regulation of decidual macrophages function in recurrent spontaneous abortion., PMID:38295895
Peripheral blood transcriptomic analysis identifies potential inflammation and immune signatures for central retinal artery occlusion., PMID:38548806
Potentials as biomarker and therapeutic target of upregulated long non-coding RNA HLA-F antisense RNA 1 in hepatitis B virus-associated hepatocellular carcinoma., PMID:38568442
Deciphering the similarities and disparities of molecular mechanisms behind respiratory epithelium response to HCoV-229E and SARS-CoV-2 and drug repurposing, a systems biology approach., PMID:38652363
FAT10 mediates the sorafenib-resistance of hepatocellular carcinoma cells by stabilizing E3 ligase NEDD4 to enhance PTEN/AKT pathway-induced autophagy., PMID:38726263
Mechanisms of USP18 deISGylation revealed by comparative analysis with its human paralog USP41., PMID:38853827
The novel non-classical HLA-F*01:12 allele identified in a Brazilian individual., PMID:39039854
Accurate multi-population imputation of MICA, MICB, HLA-E, HLA-F and HLA-G alleles from genome SNP data., PMID:39283896
Effect modification between HLA-F and CD56 markers reveals differences in survival for triple-negative breast cancer patients., PMID:39405828
TGFB2 mRNA Levels Prognostically Interact with Interferon-Alpha Receptor Activation of IRF9 and IFI27, and an Immune Checkpoint LGALS9 to Impact Overall Survival in Pancreatic Ductal Adenocarcinoma., PMID:39457004
Epigenetic age acceleration and methylation differences in IgG4-related cholangitis and primary sclerosing cholangitis., PMID:39819503
HLA-F regulates the proliferation of trophoblast via PKM2-dependent glycolysis in the pathogenesis of preeclampsia., PMID:40251569
Mechanistic insights into the role of FAT10 in modulating NCOA4-mediated ferroptosis in pancreatic acinar cells during acute pancreatitis., PMID:40374601
For research use only. Not for human or drug use.
