Catalog No.
YVV22701
Expression system
E. coli
Species
Zaire ebolavirus
Protein length
Val36-Glu351
Predicted molecular weight
36.18 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
AXF48955.1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% SKL, 1mM EDTA, 5% Trehalose, 2% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Nucleoprotein, Nucleocapsid protein, NP
Note
For research use only.
The Cellular Protein CAD is Recruited into Ebola Virus Inclusion Bodies by the Nucleoprotein NP to Facilitate Genome Replication and Transcription., PMID:32370067
Large-scale mapping of the Ebola NP and GP proteins reveals multiple immunoprevalent and conserved CD4 T-cell epitopes., PMID:32398806
Ebola Virus Inclusion Body Formation and RNA Synthesis Are Controlled by a Novel Domain of Nucleoprotein Interacting with VP35., PMID:32493824
Identification of interferon-stimulated genes that attenuate Ebola virus infection., PMID:32528005
Comparison of Zaire ebolavirus realtime RT-PCRs targeting the nucleoprotein gene., PMID:32707049
Characteristics of Ebola Virus Disease Survivor Blood and Semen in Liberia: Serology and Reverse Transcription Polymerase Chain Reaction (RT-PCR)., PMID:32894277
The two-stage interaction of Ebola virus VP40 with nucleoprotein results in a switch from viral RNA synthesis to virion assembly/budding., PMID:33141416
A paramyxovirus-like model for Ebola virus bipartite promoters., PMID:33152032
Development of a New Reverse Genetics System for Ebola Virus., PMID:33952663
Marburg and Ebola Virus mRNA 3' Untranslated Regions Contain Negative Regulators of Translation That Are Modulated by ADAR1 Editing., PMID:34346762
A computational overview on phylogenetic characterization, pathogenic mutations, and drug targets for Ebola virus disease., PMID:34563987
Structural and Functional Aspects of Ebola Virus Proteins., PMID:34684279
Functional Importance of Hydrophobic Patches on the Ebola Virus VP35 IFN-Inhibitory Domain., PMID:34835122
Generating Uniformly Cross-Reactive Ebolavirus spp. Anti-nucleoprotein Nanobodies to Facilitate Forward Capable Detection Strategies., PMID:34994194
Ebola Virus GP Activates Endothelial Cells via Host Cytoskeletal Signaling Factors., PMID:35062347
Visualizing Filoviral Nucleoproteins Using Nanobodies Fused to the Ascorbate Peroxidase Derivatives APEX2 and dEAPX., PMID:35157287
Structural insight into Marburg virus nucleoprotein-RNA complex formation., PMID:35246537
One-step single-tube accelerated quantitative nucleoprotein gene-specific reverse transcription loop-mediated isothermal gene amplification (RT-LAMP) assay for rapid, real-time & reliable clinical detection of Ebola virus., PMID:35435345
TRIM25 and ZAP target the Ebola virus ribonucleoprotein complex to mediate interferon-induced restriction., PMID:35533151
Designing a novel multi‑epitope vaccine against Ebola virus using reverse vaccinology approach., PMID:35545650
Epitope-focused immunogen design based on the ebolavirus glycoprotein HR2-MPER region., PMID:35584193
Structural insights into the interactions between lloviu virus VP30 and nucleoprotein., PMID:35649303
Assembly and transport of filovirus nucleocapsids., PMID:35900983
Ebola-Detect: A differential serodiagnostic assay for Ebola virus infections and surveillance in the presence of vaccine-induced antibodies., PMID:35901660
Detection of filovirus-reactive antibodies in Australian bat species., PMID:35972225
Role of VP30 Phosphorylation in Ebola Virus Nucleocapsid Assembly and Transport., PMID:35993739
Evidence for Viral mRNA Export from Ebola Virus Inclusion Bodies by the Nuclear RNA Export Factor NXF1., PMID:36040180
Filovirus helical nucleocapsid structures., PMID:36242583
Self-amplifying RNA vaccine protects mice against lethal Ebola virus infection., PMID:36303436
Randomized Trial of Vaccines for Zaire Ebola Virus Disease., PMID:36516078
Ebola Virus Activates IRE1α-Dependent XBP1u Splicing., PMID:36680162
Cellular and humoral immunity to Ebola Zaire glycoprotein and viral vector proteins following immunization with recombinant vesicular stomatitis virus-based Ebola vaccine (rVSVΔG-ZEBOV-GP)., PMID:36725433
Inhibiting the transcription and replication of Ebola viruses by disrupting the nucleoprotein and VP30 protein interaction with small molecules., PMID:36759643
Diagnostics of Ebola virus., PMID:36908455
Ebola virus inclusion bodies are liquid organelles whose formation is facilitated by nucleoprotein oligomerization., PMID:37306660
The 3' Untranslated Regions of Ebola Virus mRNAs Contain AU-Rich Elements Involved in Posttranscriptional Stabilization and Decay., PMID:37551415
Disruption of Ebola NP0VP35 Inclusion Body-like Structures reduce Viral Infection., PMID:37598728
Structural insights on the nucleoprotein C-terminal domain of Měnglà virus., PMID:37888996
Extracellular vesicle storm during the course of Ebola virus infection in primates., PMID:38035334
Molecular modeling and simulation studies of SELEX-derived high-affinity DNA aptamers to the Ebola virus nucleoprotein., PMID:38217874
ICTV Virus Taxonomy Profile: Filoviridae 2024., PMID:38305775
Serological evidence of zoonotic filovirus exposure among bushmeat hunters in Guinea., PMID:38755147
Impact of Ebola virus nucleoprotein on VP40 virus-like particle production: a computational approach., PMID:38796621
Intracellular Ebola virus nucleocapsid assembly revealed by in situ cryo-electron tomography., PMID:39293445
Ginkgolic acid inhibits Ebola virus transcription and replication by disrupting the interaction between nucleoprotein and VP30 protein., PMID:39716669
To be or not to be phosphorylated: understanding the role of Ebola virus nucleoprotein in the dynamic interplay with the transcriptional activator VP30 and the host phosphatase PP2A-B56., PMID:39726359
Computational study of interaction of calixarene with ebola virus structural proteins and its potential therapeutic implications., PMID:39961277
Ebola and Marburg viruses IgG detections in small ruminants and dogs from villages within outbreak areas in Gabon., PMID:40043032
Structural basis for Ebola virus nucleocapsid assembly and function regulated by VP24., PMID:40064872
Development of a Pentacistronic Ebola Virus Minigenome System., PMID:40431699
For research use only. Not for human or drug use.
