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Anti-RET Polyclonal Antibody

Catalog #:   PHC28901 Specific References (49) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: P07949
Overview

Catalog No.

PHC28901

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human RET (Leu29-Arg635).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

RET51,Proto-oncogene c-Ret,Cadherin family member 12,RET,Proto-oncogene tyrosine-protein kinase receptor Ret,CDHF12,CDHR16,PTC

Purification

Purified by antigen affinity column.

Accession

P07949

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with RET antibody (PHC28901) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 70 kDa
    Observed MW: 70 kDa
References

Expression of Membrane Targets for Therapeutics in RET-Positive Non-Small Cell Lung Cancer., PMID:40440007

P-Selectin, Vascular Endothelial Cadherin, and Vascular Cell Adhesion Molecule-1 as Novel Biomarkers for ABO Hemolytic Disease of the Fetus and Newborn., PMID:40331036

Designing Clinical Trials for Patients With Rare Cancers: Connecting the Zebras., PMID:40228175

Precision Medicine in High-Grade Serous Ovarian Cancer: Targeted Therapies and the Challenge of Chemoresistance., PMID:40141188

The treatment of autoimmune hemolytic anemia with complement inhibitor iptacopan: a case report., PMID:40115776

Comprehensive genomic profiling by liquid biopsy portrays metastatic colorectal cancer mutational landscape to predict antitumor efficacy of FOLFIRI plus cetuximab in the CAPRI-2 GOIM trial., PMID:40107157

Real-world evidence provides clinical insights into tissue-agnostic therapeutic approvals., PMID:40102447

Reactive Astrocytes Release GDNF to Promote Brain Recovery and Neuronal Survival Following Ischemic Stroke., PMID:40085335

Spitz Spindle Cell/Reed Nevus With SQSTM1 :: NTRK2 Fusion and Atypical Features in an Older Male Patient: A Case Report and Review of Literature., PMID:39980385

Previous treatment decreases efficacy of pralsetinib in RET fusion-positive non-small-cell lung cancer., PMID:39926433

Why PD-L1 expression varies between studies of lung cancer: results from a Bayesian meta-analysis., PMID:39905106

Rescue of in vitro models of CSF1R-related adult-onset leukodystrophy by iluzanebart: mechanisms and therapeutic implications of TREM2 agonism., PMID:39891235

Brief report: impact of consolidation durvalumab on unresectable non-small cell lung cancer with driver mutations., PMID:39808885

Molecular and Functional Significance of Growth Differentiation Factor-15: A Review on Cardiovascular-Kidney-Metabolic Biomarker., PMID:39781722

Rearranged During Transfection Rearrangement Detection by Fluorescence In Situ Hybridization Compared With Other Techniques in NSCLC., PMID:39507413

Evolution of treatment strategies for solid tumors with RET rearrangement in China and real-world treatment status of Non-small Cell Lung Cancer (NSCLC)., PMID:39497173

YAP Regulates HER3 Signaling-Driven Adaptive Resistance to RET Inhibitors in RET-Aberrant Cancers., PMID:39495173

Dual metal-organic-frameworks mediated resonance energy transfer for ultrasensitive electrochemiluminescence immunosensing., PMID:39467861

Targeting TREM2 signaling shows limited impact on cerebrovascular calcification., PMID:39467636

Protocol to characterize mouse dural mast cells by flow cytometry and immunofluorescence., PMID:39378155

Bronchial Sialadenoma Papilliferum in a 10-Year-Old Boy., PMID:39360355

Cost-effectiveness analysis of selpercatinib versus chemotherapy and pembrolizumab in the first-line treatment of rearranged during transfection fusion-positive non-small cell lung cancer in the United States., PMID:39352419

Detection of SEZ6, a therapeutic target, in medullary thyroid carcinoma., PMID:39324657

FK962 protects retinal ganglion cell under hypoxia/reoxygenation: Possible involvement of glial cell line-derived neurotrophic factor signaling pathway., PMID:39284507

Clinicopathological Features of CCDC6-RET and NCOA4-RET Fusions in Thyroid Cancer: A Single-Center Retrospective Cohort Study in a Chinese Population., PMID:39212716

Neutralizing antibody against GDF15 for treatment of cancer-associated cachexia., PMID:39172988

Risk of low levels of blood group antibodies mediating hemolysis in ABO-incompatible neonates with negative three hemolysis tests., PMID:39161638

Target-Driven Tissue-Agnostic Drug Approvals-A New Path of Drug Development., PMID:39061168

Top advances of the year: Targeted therapy for lung cancer., PMID:39031586

Spotlight on the treatment of non-small cell lung cancer with rare genetic alterations and brain metastasis: Current status and future perspectives., PMID:38958227

Striatal GDNF Neurons Chemoattract RET-Positive Dopamine Axons at Seven Times Farther Distance Than Medium Spiny Neurons., PMID:38920687

Electrochemiluminescence resonance energy transfer detection of HBsAg based on Co doped 3D porous luminol-based conjugates and quencher UiO-66-NH2@Au., PMID:38838601

CNS Protective Effect of Selpercatinib in First-Line RET Fusion-Positive Advanced Non-Small Cell Lung Cancer., PMID:38828957

The evolving landscape of tissue-agnostic therapies in precision oncology., PMID:38814103

Electrochemiluminescence quenching effect of Cu2O towards flower-like ferric ion-doped g-C3N4 and its application for Cyfra21-1 immunosensing., PMID:38805945

Experimental Study of Interference in Calcitonin Testing: A Case Report and Literature Review., PMID:38798210

Beyond Chemoimmunotherapy in Advanced Non-Small Cell Lung Cancer: New Frontiers, New Challenges., PMID:38781566

Anti-PD-L1 antibody TQB2450 combined with tyrosine kinase receptor inhibitor AL2846 for immunotherapy-refractory advanced hepatocellular carcinoma and esophageal squamous cell carcinoma: A prospective phase 1b cohort study., PMID:38781433

Efficacy and safety of pyrotinib combined with albumin-bound paclitaxel as first-line treatment for HER2-positive metastatic breast cancer in patients previously treated with adjuvant and/or neoadjuvant trastuzumab therapy: The stage 1 results of a single-arm, phase 2 prospective clinical trial., PMID:38738791

Prothrombotic autoantibodies targeting platelet factor 4/polyanion are associated with pediatric cerebral malaria., PMID:38652559

The emerging perioperative treatment paradigm for non-small cell lung cancer: a narrative review., PMID:38372058

Efficacy of first-line treatment options beyond RET-TKIs in advanced RET-rearranged non-small cell lung cancer: A multi-center real-world study., PMID:38349001

Baseline ctDNA gene alterations as a biomarker of survival after panitumumab and chemotherapy in metastatic colorectal cancer., PMID:38347302

Is Immunotherapy Beneficial in Patients with Oncogene-Addicted Non-Small Cell Lung Cancers? A Narrative Review., PMID:38339280

Extended Induction and Prognostic Indicators of Response in Patients Treated with Mirikizumab with Moderately to Severely Active Ulcerative Colitis in the LUCENT Trials., PMID:38271613

Selpercatinib or Chemotherapy in RET Fusion-Positive NSCLC. Reply., PMID:38265654

Selpercatinib or Chemotherapy in RET Fusion-Positive NSCLC., PMID:38265653

Update on current diagnosis and management of anaplastic thyroid carcinoma., PMID:38179406

Placenta microRNA profile of patient with Obstetric Antiphospholipid Syndrome., PMID:38155384

Datasheet

Document Download

Anti-RET Polyclonal Antibody.pdf

 

$ 170
Product specifications
50 μg 170 100 μg 280

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Anti-RET Polyclonal Antibody [PHC28901]
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