Catalog No.
YHD12001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Glu152
Predicted molecular weight
19.31 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P15531
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NDPKA, NME1, NDP kinase A, Nucleoside diphosphate kinase A, Granzyme A-activated DNase, NM23, Metastasis inhibition factor nm23, GAAD, Tumor metastatic process-associated protein, NDK A, NM23-H1
Note
For research use only.
A Functional Network Model of the Metastasis Suppressor PEBP1/RKIP and Its Regulators in Breast Cancer Cells., PMID:34885208
Predicted expression of genes involved in the thiopurine metabolic pathway and azathioprine discontinuation due to myelotoxicity., PMID:35118815
Long-chain fatty acyl coenzyme A inhibits NME1/2 and regulates cancer metastasis., PMID:35259022
MicroRNA-139-5p negatively regulates NME1 expression in hepatocellular carcinoma cells., PMID:35438846
Identification of Significant Secreted or Membrane-Located Proteins in Laryngeal Squamous Cell Carcinoma., PMID:35655921
Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems., PMID:35939247
Elucidation of TRIM25 ubiquitination targets involved in diverse cellular and antiviral processes., PMID:36067236
Characterization of Vemurafenib-Resistant Melanoma Cell Lines Reveals Novel Hallmarks of Targeted Therapy Resistance., PMID:36077308
Assessment of the Anticancer Potentials of the Free and Metal-Organic Framework (UiO-66) - Delivered Phycocyanobilin., PMID:36087776
Extracellular vesicle expansion of PMIS-miR-210 expression inhibits colorectal tumour growth via apoptosis and an XIST/NME1 regulatory mechanism., PMID:36116139
Blood-Brain Barrier Disintegration in Growth-Restricted Fetuses with Brain Sparing Effect., PMID:36293204
Molecular Indicators of Blood-Brain Barrier Breakdown and Neuronal Injury in Pregnancy Complicated by Fetal Growth Restriction., PMID:36430274
LHPP, a risk factor for major depressive disorder, regulates stress-induced depression-like behaviors through its histidine phosphatase activity., PMID:36460727
Phosphohistidine signaling promotes FAK-RB1 interaction and growth factor-independent proliferation of esophageal squamous cell carcinoma., PMID:36513743
Does the Blood-Brain Barrier Integrity Change in Regard to the Onset of Fetal Growth Restriction?, PMID:36768287
LINKIN-associated proteins necessary for tissue integrity during collective cell migration., PMID:36798316
The Loss of YTHDC1 in Gut Macrophages Exacerbates Inflammatory Bowel Disease., PMID:36922750
Identification of novel urine proteomic biomarkers for high stamina in high-altitude adaptation., PMID:37250129
Machine learning modeling and prognostic value analysis of invasion-related genes in cutaneous melanoma., PMID:37267825
A Unique Mode of Coenzyme A Binding to the Nucleotide Binding Pocket of Human Metastasis Suppressor NME1., PMID:37298313
Mechanisms of action of NME metastasis suppressors - a family affair., PMID:37353690
Integrin beta-like 1 mediates fibroblast-cardiomyocyte crosstalk to promote cardiac fibrosis and hypertrophy., PMID:37395147
Spatially resolved expression landscape and gene-regulatory network of human gastric corpus epithelium., PMID:37402315
Mass Spectrometry as a Quantitative Proteomic Analysis Tool for the Search for Temporal Lobe Epilepsy Biomarkers: A Systematic Review., PMID:37446307
Manipulating RKIP reverses the metastatic potential of breast cancer cells., PMID:37469399
Glaucoma-Associated CDR1 Peptide Promotes RGC Survival in Retinal Explants through Molecular Interaction with Acidic Leucine Rich Nuclear Phosphoprotein 32A (ANP32A)., PMID:37509196
Helicase-like transcription factor (Hltf)-deletion activates Hmgb1-Rage axis and granzyme A-mediated killing of pancreatic β cells resulting in neonatal lethality., PMID:37624843
Nucleoside diphosphate kinases 1 and 2 regulate a protective liver response to a high-fat diet., PMID:37672589
Heat-shock protein 90α protects NME1 against degradation and suppresses metastasis of breast cancer., PMID:37731021
Metastasis suppressor genes in clinical practice: are they druggable?, PMID:37749308
The ASH1L-AS1-ASH1L axis controls NME1-mediated activation of the RAS signaling in gastric cancer., PMID:37805663
NSUN6 Regulates NM23-H1 Expression in an m5C Manner to Affect Epithelial-Mesenchymal Transition in Lung Cancer., PMID:38029727
PRUNE1 and NME/NDPK family proteins influence energy metabolism and signaling in cancer metastases., PMID:38180572
UCHL-3 as a potential biomarker of ovarian cancer., PMID:38266402
NME1 and DCC variants are associated with susceptibility and tumor characteristics in Mexican patients with colorectal cancer., PMID:38556604
Elevated extracellular vesicular Nm23-H1 subdues the pro-migratory potential of breast cancer cell-derived extracellular vesicles., PMID:38723736
Identifying Candidate Gene Drivers Associated with Relapse in Pediatric T-Cell Acute Lymphoblastic Leukemia Using a Gene Co-Expression Network Approach., PMID:38730619
[Progress in enrichment methods for protein N-phosphorylation]., PMID:38966971
Kinase-catalyzed biotinylation for discovery and validation of substrates to multispecificity kinases NME1 and NME2., PMID:39032654
Histidine Phosphorylation: Protein Kinases and Phosphatases., PMID:39063217
MGA deletion leads to Richter's transformation by modulating mitochondrial OXPHOS., PMID:39083585
Long Noncoding RNA NKX2-1-AS1 Accelerates Non-Small Cell Lung Cancer Progression through the miR-589-5p/NME1 Axis., PMID:39117986
Mitochondrial NME6: A Paradigm Change within the NME/NDP Kinase Protein Family?, PMID:39120309
Proteomic profiling of cerebrospinal fluid reveals TKT as a potential biomarker for medulloblastoma., PMID:39251709
Parthenolide Inhibits Tumor Cell Growth and Metastasis in Melanoma A2058 Cells., PMID:39415578
Genetic Influence of the Brain on Muscle Structure: A Mendelian Randomization Study of Sarcopenia., PMID:39535371
Nitidine chloride inhibits the progression of hepatocellular carcinoma by suppressing IGF2BP3 and modulates metabolic pathways in an m6A-dependent manner., PMID:39910429
P21-Activated Kinase 1 (PAK1) Modulates Therapeutic Response to Ionizing Radiation in Head and Neck Squamous Cell Carcinoma Cells., PMID:40099538
Identifying therapeutic target genes for diabetic retinopathy using systematic druggable genome-wide Mendelian randomization., PMID:40301928
Serendipitous and Systematic Chemoproteomic Discovery of MBLAC2, HINT1, and NME1-4 Inhibitors from Histone Deacetylase-Targeting Pharmacophores., PMID:40340313
For research use only. Not for human or drug use.
