Catalog No.
PHC27401
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PFN1 (Met1-Gln139).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Profilin-1,Profilin I,Epididymis tissue protein Li 184a,PFN1
Purification
Purified by antigen affinity column.
Accession
P07737
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Serum anti-CFL1, anti-EZR, and anti-CYPA autoantibody as diagnostic markers in ovarian cancer., PMID:38684875
Complex changes in serum protein levels in COVID-19 convalescents., PMID:38396092
The identification of high-performing antibodies for Profilin-1 for use in Western blot, immunoprecipitation and immunofluorescence., PMID:37576538
Inhibition of Cathepsin B and SAPC Secreted by HIV-Infected Macrophages Reverses Common and Unique Apoptosis Pathways., PMID:34994563
The proteomes of endometrial stromal cell-derived extracellular vesicles following a decidualizing stimulus define the cells' potential for decidualization success., PMID:34524461
Profilin 1 knockdown prevents ischemic brain damage by promoting M2 microglial polarization associated with the RhoA/ROCK pathway., PMID:32291804
Construction of dual nanomedicines for the imaging and alleviation of atherosclerosis., PMID:31852323
Cerebral adrenoleukodystrophy is associated with loss of tolerance to profilin., PMID:30829395
Protein phosphatase 1 dephosphorylates profilin-1 at Ser-137., PMID:22479341
Neuronal profilin isoforms are addressed by different signalling pathways., PMID:22470532
Profilin 1 is a potential biomarker for bladder cancer aggressiveness., PMID:22159600
In birds, profilin-2a is ubiquitously expressed and contributes to actin-based motility., PMID:19258389
Construction of cell surface-engineered yeasts displaying antigen to detect antibodies by immunofluorescence and yeast-ELISA., PMID:18542951
Novel testis-expressed profilin IV associated with acrosome biogenesis and spermatid elongation., PMID:15591451
Anti-actin antibodies generated against profilin:actin distinguish between non-filamentous and filamentous actin, and label cultured cells in a dotted pattern., PMID:15506565
Vinculin, VASP, and profilin are coordinately regulated during actin remodeling in epithelial cells, which requires de novo protein synthesis and protein kinase signal transduction pathways., PMID:15174098
Profilin I colocalizes with speckles and Cajal bodies: a possible role in pre-mRNA splicing., PMID:12729790
Molecular and structural analysis of the panallergen profilin B cell epitopes defined by monoclonal antibodies., PMID:12202397
Activation of DNA synthesis and AP-1 by profilin, an actin-binding protein, via binding to a cell surface receptor in cultured rat mesangial cells., PMID:10966486
cAMP-dependent protein kinase phosphorylation of EVL, a Mena/VASP relative, regulates its interaction with actin and SH3 domains., PMID:10945997
Expression of profilin, an actin-binding protein, in rat experimental glomerulonephritis and its upregulation by basic fibroblast growth factor in cultured rat mesangial cells., PMID:10703666
Profilin is required for optimal actin-dependent transcription of respiratory syncytial virus genome RNA., PMID:10623728
Quantification of profilins by a monoclonal antibody-based sandwich ELISA., PMID:10556691
Coordinate induction of the actin cytoskeletal regulatory proteins gelsolin, vasodilator-stimulated phosphoprotein, and profilin during capillary morphogenesis in vitro., PMID:10328950
Characterization of a mutant profilin with reduced actin-binding capacity: effects in vitro and in vivo., PMID:9223371
p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin., PMID:9214622
Production and characterization of profilin monoclonal antibodies., PMID:9208051
Co-ordinate regulation of the cytoskeleton in 3T3 cells overexpressing thymosin-beta4., PMID:9331222
Differential colocalization of profilin with microfilaments in PtK2 cells., PMID:9186014
Molecular and structural analysis of a continuous birch profilin epitope defined by a monoclonal antibody., PMID:8939935
Induction of IgE antibodies in mice and rhesus monkeys with recombinant birch pollen allergens: different allergenicity of Bet v 1 and Bet v 2., PMID:8939154
Mena, a relative of VASP and Drosophila Enabled, is implicated in the control of microfilament dynamics., PMID:8861907
Enhanced glomerular profilin gene and protein expression in experimental mesangial proliferative glomerulonephritis., PMID:8651905
Profilin forms tetramers that bind to G-actin., PMID:8573117
The proline-rich focal adhesion and microfilament protein VASP is a ligand for profilins., PMID:7737110
Dynamic actin structures stabilized by profilin., PMID:8108438
Location of profilin at presynaptic sites in the cerebellar cortex; implication for the regulation of the actin-polymerization state during axonal elongation and synaptogenesis., PMID:8106880
Distribution of profilin in fibroblasts correlates with the presence of highly dynamic actin filaments., PMID:1581979
Cortical microfilament proteins and the dynamics of the plasma membrane., PMID:1811265
Interactions among serum vitamin D binding protein, monomeric actin, profilin, and profilactin., PMID:2910852
Characterization of renatured profilin purified by urea elution from poly-L-proline agarose columns., PMID:2611892
Reversible binding of actin to gelsolin and profilin in human platelet extracts., PMID:3040771
For research use only. Not for human or drug use.
