Catalog No.
PHC27201
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human HEXB (Lys315-Tyr456).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
N-Acetyl-β-glucosaminidase (NAG),chitobiase,NAG,Beta-hexosaminidase subunit beta,Beta-N-acetylhexosaminidase subunit beta,N-acetyl-beta-glucosaminidase subunit beta,Cervical cancer proto-oncogene 7 protein,Hexosaminidase subunit B,HCC-7,HEXB
Purification
Purified by antigen affinity column.
Accession
P07686
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Identification and characterization of a residual host cell protein hexosaminidase B associated with N-glycan degradation during the stability study of a therapeutic recombinant monoclonal antibody product., PMID:33476097
Modulation of Hematopoietic Lineage Specification Impacts TREM2 Expression in Microglia-Like Cells Derived From Human Stem Cells., PMID:28683563
Transient and Prolonged Response of Chicken Cecum Mucosa to Colonization with Different Gut Microbiota., PMID:27685470
Circadian profiling in two mouse models of lysosomal storage disorders; Niemann Pick type-C and Sandhoff disease., PMID:26467605
Gene expression analysis in human breast cancer associated blood vessels., PMID:23056178
Thymic alterations in GM2 gangliosidoses model mice., PMID:20856892
Therapeutic evaluation of GM2 gangliosidoses by ELISA using anti-GM2 ganglioside antibodies., PMID:17196574
Inefficiency in GM2 ganglioside elimination by human lysosomal beta-hexosaminidase beta-subunit gene transfer to fibroblastic cell line derived from Sandhoff disease model mice., PMID:16880605
Sequencing, expression, and enzymatic characterization of beta-hexosaminidase in rabbit lacrimal gland and primary cultured acinar cells., PMID:15483268
An inversion of 25 base pairs causes feline GM2 gangliosidosis variant., PMID:15081585
Possible role of autoantibodies in the pathophysiology of GM2 gangliosidoses., PMID:14722612
Western blotting analysis of the beta-hexosaminidase alpha- and beta-subunits in cultured fibroblasts from cases of various forms of GM2 gangliosidosis., PMID:12027830
Retrovirus-mediated transfer and expression of beta-hexosaminidase alpha-chain cDNA in human fibroblasts from G(M2)-gangliosidosis B1 variant., PMID:11560770
Distribution of enzyme-bearing cells in GM2 gangliosidosis mice: regionally specific pattern of cellular infiltration following bone marrow transplantation., PMID:10672323
I. Abnormalities in cells of the testis, efferent ducts, and epididymis in juvenile and adult mice with beta-hexosaminidase A and B deficiency., PMID:10591618