Catalog No.
PHC27201
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human HEXB (Lys315-Tyr456).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
N-Acetyl-β-glucosaminidase (NAG),chitobiase,NAG,Beta-hexosaminidase subunit beta,Beta-N-acetylhexosaminidase subunit beta,N-acetyl-beta-glucosaminidase subunit beta,Cervical cancer proto-oncogene 7 protein,Hexosaminidase subunit B,HCC-7,HEXB
Purification
Purified by antigen affinity column.
Accession
P07686
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Note
For research use only.
I. Abnormalities in cells of the testis, efferent ducts, and epididymis in juvenile and adult mice with beta-hexosaminidase A and B deficiency., PMID:10591618
Distribution of enzyme-bearing cells in GM2 gangliosidosis mice: regionally specific pattern of cellular infiltration following bone marrow transplantation., PMID:10672323
Retrovirus-mediated transfer and expression of beta-hexosaminidase alpha-chain cDNA in human fibroblasts from G(M2)-gangliosidosis B1 variant., PMID:11560770
Western blotting analysis of the beta-hexosaminidase alpha- and beta-subunits in cultured fibroblasts from cases of various forms of GM2 gangliosidosis., PMID:12027830
Possible role of autoantibodies in the pathophysiology of GM2 gangliosidoses., PMID:14722612
An inversion of 25 base pairs causes feline GM2 gangliosidosis variant., PMID:15081585
Sequencing, expression, and enzymatic characterization of beta-hexosaminidase in rabbit lacrimal gland and primary cultured acinar cells., PMID:15483268
Inefficiency in GM2 ganglioside elimination by human lysosomal beta-hexosaminidase beta-subunit gene transfer to fibroblastic cell line derived from Sandhoff disease model mice., PMID:16880605
Therapeutic evaluation of GM2 gangliosidoses by ELISA using anti-GM2 ganglioside antibodies., PMID:17196574
Thymic alterations in GM2 gangliosidoses model mice., PMID:20856892
Gene expression analysis in human breast cancer associated blood vessels., PMID:23056178
Circadian profiling in two mouse models of lysosomal storage disorders; Niemann Pick type-C and Sandhoff disease., PMID:26467605
Transient and Prolonged Response of Chicken Cecum Mucosa to Colonization with Different Gut Microbiota., PMID:27685470
Modulation of Hematopoietic Lineage Specification Impacts TREM2 Expression in Microglia-Like Cells Derived From Human Stem Cells., PMID:28683563
Identification and characterization of a residual host cell protein hexosaminidase B associated with N-glycan degradation during the stability study of a therapeutic recombinant monoclonal antibody product., PMID:33476097
For research use only. Not for human or drug use.
