Catalog No.
YHK44001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ser208
Predicted molecular weight
25.50 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9BXK5
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Protein Mil1, MIL1, Bcl-rambo, BCL2L13, Bcl-2-like protein 13, Bcl2-L-13
Note
For research use only.
Selective binding of mitophagy receptor protein Bcl-rambo to LC3/GABARAP family proteins., PMID:32828302
LncRNA FOXD3-AS1 knockdown protects against cerebral ischemia/reperfusion injury via miR-765/BCL2L13 axis., PMID:33068927
Differential effects of risuteganib and bevacizumab on AMD cybrid cells., PMID:33075294
BCL2L13: physiological and pathological meanings., PMID:33201252
Mitophagy Receptors in Tumor Biology., PMID:33262988
Mitophagy in tumorigenesis and metastasis., PMID:33580835
By targeting apoptosis facilitator BCL2L13, microRNA miR-484 alleviates cerebral ischemia/reperfusion injury-induced neuronal apoptosis in mice., PMID:33724167
Anti-VEGF Drugs Influence Epigenetic Regulation and AMD-Specific Molecular Markers in ARPE-19 Cells., PMID:33921543
Down-regulation of BCL2L13 renders poor prognosis in clear cell and papillary renal cell carcinoma., PMID:34193180
The multifaceted regulation of mitophagy by endogenous metabolites., PMID:34583624
Mycobacterium bovis induces mitophagy to suppress host xenophagy for its intracellular survival., PMID:34720021
Effects of fluoroquinolones and tetracyclines on mitochondria of human retinal MIO-M1 cells., PMID:34856207
Analysis of the resistance of small peptides from Periplaneta americana to hydrogen peroxide-induced apoptosis in human ovarian granular cells based on RNA-seq., PMID:34915048
[Advances in the study of mitophagy-related receptor proteins]., PMID:34961877
Serum miR-96-5p is a novel and non-invasive marker of acute myocardial infarction associated with coronary artery disease., PMID:35109756
Therapeutic regulation of autophagy in hepatic metabolism., PMID:35127371
LncRNA SNHG14 is beneficial to oxygen glucose deprivation/reoxygenation-induced neuro-2a cell injury via mir-98-5p sequestration-caused BCL2L13 upregulation., PMID:35678981
Identification of Critical Genes and Pathways for Influenza A Virus Infections via Bioinformatics Analysis., PMID:35893690
PGAM5 interacts with Bcl-rambo and regulates apoptosis and mitophagy., PMID:36075447
Differential Epigenetic Status and Responses to Stressors between Retinal Cybrids Cells with African versus European Mitochondrial DNA: Insights into Disease Susceptibilities., PMID:36078063
Small Peptides from Periplaneta americana Inhibits Oxidative Stress-Induced KGN Cell Apoptosis by Regulating Mitochondrial Function Through Bcl2L13., PMID:36085549
The protective effect of inhibiting mitochondrial fission on the juvenile rat brain following PTZ kindling through inhibiting the BCL2L13/LC3 mitophagy pathway., PMID:36094724
The Activity of Vitamin C Against Ovarian Cancer Cells Is Enhanced by Hyperthermia., PMID:36288898
Biological properties of the BCL-2 family protein BCL-RAMBO, which regulates apoptosis, mitochondrial fragmentation, and mitophagy., PMID:36589739
A role for BCL2L13 and autophagy in germline purifying selection of mtDNA., PMID:36608143
Deterioration of mitochondrial biogenesis and degradation in the endometrium is a cause of subfertility in cows., PMID:36645869
Does Exercise Regulate Autophagy in Humans? A Systematic Review and Meta-Analysis., PMID:40395322
High-intensity interval training in the form of isometric contraction improves fatigue resistance in dystrophin-deficient muscle., PMID:37184335
Investigation of enzalutamide, docetaxel, and cabazitaxel resistance in the castration resistant prostate cancer cell line C4 using genome-wide CRISPR/Cas9 screening., PMID:37270558
Significant role of circRNA BBS9 in chronic obstructive pulmonary disease via miRNA-103a-3p/BCL2L13., PMID:37442983
Genome-wide scan for runs of homozygosity in South American Camelids., PMID:37605116
BCL2L13 promotes mitophagy through DNM1L-mediated mitochondrial fission in glioblastoma., PMID:37660127
PLK1 as a cooperating partner for BCL2-mediated antiapoptotic program in leukemia., PMID:37679323
MTFP1 is a mitophagy receptor that operates in PINK1/PRKN-dependent mitophagy and promotes oral cancer cell survival., PMID:40395309
ARL6IP1 gene delivery reduces neuroinflammation and neurodegenerative pathology in hereditary spastic paraplegia model., PMID:37934410
Mitophagy Decreases in the Peripheral Vestibular System of Aged C57BL/6J Mice., PMID:38148055
Did mitophagy follow the origin of mitochondria?, PMID:38361280
Molecular Characterization and Expression Changes of the bcl2l13 Gene in Response to Hypoxia in Megalobrama amblycephala., PMID:38392190
YME1L-mediated mitophagy protects renal tubular cells against cellular senescence under diabetic conditions., PMID:38494498
RNA-binding proteins potentially regulate the alternative splicing of apoptotic genes during knee osteoarthritis progression., PMID:38504181
MiR-449b-5p Ameliorates Hypoxia-induced Cardiomyocyte Injury through Activating PI3K/AKT Pathway by Targeting BCL2L13., PMID:38581629
Lack of compensatory mitophagy in skeletal muscles during sepsis., PMID:38748778
o8G-miR-6513-5p/BCL2L13 Axis Regulates Mitophagy during Oxidative Stress in the Human Saphenous Vein Endothelial Cells., PMID:39307929
Clinical and molecular cytogenetic findings of cat eye syndrome and a 2-year-old patient with congenital aural atresia and hearing loss., PMID:39402511
Proteomics reveals that nanoplastics with different sizes induce hepatocyte apoptosis in mice through distinct mechanisms involving mitophagy dysregulation and cell cycle arrest., PMID:39539253
AMPK regulates Bcl2-L-13-mediated mitophagy induction for cardioprotection., PMID:39580803
Mitophagosomes induced during EV-D68 infection promote viral nonlytic release., PMID:39677747
TAM-derived exosomal miR-589-3p accelerates ovarian cancer progression through BCL2L13., PMID:39985077
Phosphorylation of BCL2L13 by PRKAA2/AMPKα2 activates mitophagy in pressure-overloaded heart., PMID:39995141
Epimedii Folium and Ligustri Lucidi Fructus synergistically delay renal aging through AMPK/ULK1/Bcl2L13-mediated mitophagy., PMID:40122318