Catalog No.
YHC17701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp341-Asn664
Predicted molecular weight
39.56 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P05771
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PKC-beta, PRKCB1, PKC-B, PKCB, PRKCB, Protein kinase C beta type
Note
For research use only.
PRKCB is relevant to prognosis of lung adenocarcinoma through methylation and immune infiltration., PMID:35567329
Identification of significant genes with a poor prognosis in skin cutaneous malignant melanoma based on a bioinformatics analysis., PMID:35571409
Integrated Analysis of Multiple Microarray Studies to Identify Core Gene-Expression Signatures Involved in Tubulointerstitial Injury in Diabetic Nephropathy., PMID:35592524
Screening of crosstalk and pyroptosis-related genes linking periodontitis and osteoporosis based on bioinformatics and machine learning., PMID:35990678
Stellera chamaejasme L. extracts in the treatment of glioblastoma cell lines: Biological verification based on a network pharmacology approach., PMID:36059675
Validation of PRKCB Immunohistochemistry as a Biomarker for the Diagnosis of Ewing Sarcoma., PMID:36062956
LncRNA HOTAIRM1 Involved in Nano NiO-Induced Pulmonary Fibrosis via Regulating PRKCB DNA Methylation-Mediated JNK/c-Jun Pathway., PMID:36066426
Genome-wide Mendelian randomization identifies actionable novel drug targets for psychiatric disorders., PMID:36114287
Ageing-Associated Transcriptomic Alterations in Peri-Implantitis Pathology: A Bioinformatic Study., PMID:36267464
Integrated bioinformatics analysis reveals novel key biomarkers in diabetic nephropathy., PMID:36385790
Neutrophilic granulocyte-derived B-cell activating factor supports B cells in skin lesions in hidradenitis suppurativa., PMID:36481267
PKCβ Facilitates Leukemogenesis in Chronic Lymphocytic Leukaemia by Promoting Constitutive BCR-Mediated Signalling., PMID:36497487
Analysis of Intrinsic Breast Cancer Subtypes: The Clinical Utility of Epigenetic Biomarkers and TP53 Mutation Status in Triple-Negative Cases., PMID:36499753
Perinatal Fat-Diets Increased Angiotensin II-Mediated Ca2+ through PKC-L-Type Calcium Channel Axis in Resistance Arteries via Agtr1a-Prkcb Gene Methylation., PMID:36615902
Identification of radiation responsive RBC membrane associated proteins (RMAPs) in whole-body γ-irradiated New Zealand white rabbits., PMID:36718137
Integrated genetic and clinical prognostic factors for aggressive adult T-cell leukemia/lymphoma., PMID:36794502
Molecular mechanisms of atrazine toxicity on H19-7 hippocampal neurons revealed by integrated miRNA and mRNA "omics"., PMID:36841081
HBXIP blocks myosin-IIA assembly by phosphorylating and interacting with NMHC-IIA in breast cancer metastasis., PMID:36970214
Study on the Key Genes and Molecular Mechanisms of IL-27 Promoting Keratinocytes Proliferation Based on Transcriptome Sequencing., PMID:37309428
[Therapeutic mechanism of Guizhi Gancao Decoction for heart failure: a network pharmacology-based analysis]., PMID:37313819
Histologic and Genetic Features of 51 Melanocytic Neoplasms With Protein Kinase C Fusion Genes., PMID:37474004
Comprehensive analysis of the clinical and prognostic significance of SFRP1 and PRKCB expression in non-small cell lung cancer: a retrospective analysis., PMID:37505453
LncRNA AP000487.1 regulates PRKCB DNA methylation-mediated TLR4/MyD88/NF-κB pathway in Nano NiO-induced collagen formation in BEAS-2B cells., PMID:37528634
Exploration of potential targets and mechanisms of naringenin in the treatment of nonalcoholic fatty liver disease through network pharmacology., PMID:37861538
Identification of novel N7-methylguanine-related gene signatures associated with ulcerative colitis and the association with biological therapy., PMID:37889323
Detection of microRNAs expression signatures in vitreous humor of intraocular tuberculosis., PMID:37906423
Integrating network pharmacology, molecular docking and simulation approaches with machine learning reveals the multi-target pharmacological mechanism of Berberis integerrima against diabetic nephropathy., PMID:38379386
Mechanism of Astragalus mongholicus Bunge ameliorating cerebral ischemia-reperfusion injury: Based on network pharmacology analysis and experimental verification., PMID:38588987
The Association of Redox Regulatory Drug Target Genes with Psychiatric Disorders: A Mendelian Randomization Study., PMID:38671846
GNB4 Silencing Promotes Pyroptosis to Inhibit the Development of Glioma by Activating cGAS-STING Pathway., PMID:38814382
Identifying drug candidates for pancreatic ductal adenocarcinoma based on integrative multiomics analysis., PMID:38989421
Exploring the high-quality ingredients and mechanisms of Da Chuanxiong Formula in the treatment of neuropathic pain based on network pharmacology, molecular docking, and molecular dynamics simulation., PMID:39068852
In-depth transcriptome profiling of Cherry Valley duck lungs exposed to chronic heat stress., PMID:39104549
[Screening and validation of therapeutic targets for chronic sinusitis with nasal polyps based on proteomics]., PMID:39107122
Natural killer cell-associated prognosis model characterizes immune landscape and treatment efficacy of diffuse large B cell lymphoma., PMID:39111113
Proteomics identifies potential immunological drivers of postinfection brain atrophy and cognitive decline., PMID:39143319
Prenatal opioid exposure significantly impacts placental protein kinase C (PKC) and drug transporters, leading to drug resistance and neonatal opioid withdrawal syndrome., PMID:39238930
PRKCB methylation: a potential biomarker of MDD with childhood chronic stress, a cross-sectional study in drug-naive, first-episode adolescent MDD., PMID:39342638
Anti-liver cancer therapeutic targets and safety of usenamine A in experimental liver cancer., PMID:39360781
Genome-wide DNA methylation profiling reveals a novel hypermethylated biomarker PRKCB in gastric cancer., PMID:39496833
A proteogenomic analysis of cervical cancer reveals therapeutic and biological insights., PMID:39578447
Dynamics of the blood plasma proteome during hyperacute HIV-1 infection., PMID:39632834
Unveiling the substantial role of rutin in the management of drug-induced nephropathy using network pharmacology and molecular docking., PMID:39733639
A genome-wide association study identified PRKCB as a causal gene and therapeutic target for Mycobacterium avium complex disease., PMID:39848245
Tianqi Yizhi Granule alleviates cognitive dysfunction and neurodegeneration in SAMP8 mice via the PKC/ERK pathway., PMID:39986222
Pharmacological targets and therapeutic mechanisms of Arabic gum in treating diabetic wounds: insights from network pharmacology and experimental validation., PMID:40051560
Genomic and Transcriptomic Characterization of Protein Kinase C Fusion Melanocytic Neoplasms With Distinctive Hypopigmented Histomorphology: A Single-Institution Study., PMID:40109002
Gene expression analysis in circulating tumour cells to determine resistance to CDK4/6 inhibitors plus endocrine therapy in HR + /HER2- metastatic breast cancer patients., PMID:40186268
Effects of Asiatic acid on brain cancer by altering astrocytes and the AKT1-PRKCB signaling pathway: A genomic and network pharmacology perspective., PMID:40252893
Identification of genetic signatures of positive selection in apes linked to life-history trait adaptations., PMID:40320481
For research use only. Not for human or drug use.
