Catalog No.
YHE56101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser50-Lys525
Predicted molecular weight
55.06 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P48163
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ME1, NADP-dependent malic enzyme, NADP-ME, Malic enzyme 1
Note
For research use only.
Malic Enzyme 1 (ME1) Promotes Adiposity and Hepatic Steatosis and Induces Circulating Insulin and Leptin in Obese Female Mice., PMID:37047583
Mucosal immunization with lactiplantibacillus plantarum-displaying recombinant SARS-CoV-2 epitopes on the surface induces humoral and mucosal immune responses in mice., PMID:37161468
Three genes expressed in relation to lipid metabolism considered as potential biomarkers for the diagnosis and treatment of diabetic peripheral neuropathy., PMID:37248406
Metabolomic and transcriptomic analyses of Fmo5-/- mice reveal roles for flavin-containing monooxygenase 5 (FMO5) in NRF2-mediated oxidative stress response, unfolded protein response, lipid homeostasis, and carbohydrate and one-carbon metabolism., PMID:37267233
Biphenotypic Sinonasal Sarcoma with a Novel PAX7::PPARGC1 Fusion: Expanding the Spectrum of Gene Fusions Beyond the PAX3 Gene., PMID:37378830
Serial Sampling of the Small Airway Epithelium to Identify Persistent Smoking-dysregulated Genes., PMID:37531632
PGAM5 deacetylation mediated by SIRT2 facilitates lipid metabolism and liver cancer proliferation., PMID:37580952
ACLY as a modulator of liver cell functions and its role in Metabolic Dysfunction-Associated Steatohepatitis., PMID:37620891
Improved tropoelastin synthesis in the skin by codon optimization and nucleotide modification of tropoelastin-encoding synthetic mRNA., PMID:37650117
Depletion of G9A attenuates imiquimod-induced psoriatic dermatitis via targeting EDAR-NF-κB signaling in keratinocyte., PMID:37739945
BloodChIP Xtra: an expanded database of comparative genome-wide transcription factor binding and gene-expression profiles in healthy human stem/progenitor subsets and leukemic cells., PMID:37870453
DOT1L interaction partner AF10 controls patterning of H3K79 methylation and RNA polymerase II to maintain cell identity., PMID:37995701
A novel metabolism-related gene signature in patients with hepatocellular carcinoma., PMID:38025761
Alternative Polyadenylation of Malic Enzyme 1 Is Essential for Accelerated Adipogenesis., PMID:38088871
Insights into the influence of diet and genetics on feed efficiency and meat production in sheep., PMID:38112204
Inactivation of Malic Enzyme 1 in Endothelial Cells Alleviates Pulmonary Hypertension., PMID:38314588
Glutamine catabolism supports amino acid biosynthesis and suppresses the integrated stress response to promote photoreceptor survival., PMID:38586045
ER-associated degradation adapter Sel1L is required for CD8+ T cell function and memory formation following acute viral infection., PMID:38687642
Identification of potential key lipid metabolism-related genes involved in tubular injury in diabetic kidney disease by bioinformatics analysis., PMID:38691241
Cytotoxic sigma-2 ligands trigger cancer cell death via cholesterol-induced-ER-stress., PMID:38697978
An orchestrated ethylene-gibberellin signaling cascade contributes to mesocotyl elongation and emergence of rice direct seeding., PMID:38751025
Histone demethylase KDM4A mediating macrophage polarization: A potential mechanism of trichloroethylene induced liver injury., PMID:38800986
Higher expression of TSR2 aggravating hypertension via the PPAR signaling pathway., PMID:38814181
G6PD and ACSL3 are synthetic lethal partners of NF2 in Schwann cells., PMID:38879607
Epithelial cells maintain memory of prior infection with Streptococcus pneumoniae through di-methylation of histone H3., PMID:38956024
Metabolic and transcriptomic reprogramming during contact inhibition-induced quiescence is mediated by YAP-dependent and YAP-independent mechanisms., PMID:39117624
Identification and analysis of significant genes in nonalcoholic steatohepatitis-hepatocellular carcinoma transformation: Bioinformatics analysis and machine learning approach., PMID:39142007
Compensatory activity of the PC-ME1 metabolic axis underlies differential sensitivity to mitochondrial complex I inhibition., PMID:39375345
RNA methyltransferase NSUN2-mediated m5C methylation promotes Cr(VI)-induced malignant transformation and lung cancer by accelerating metabolism reprogramming., PMID:39395236
ME2 Deficiency Is Associated With Recessive Neurodevelopmental Disorder., PMID:39401966
Novel pharmacologic inhibition of lysine-specific demethylase 1 as a potential therapeutic for glioblastoma., PMID:39501082
Two Regions with Different Expression of Lipogenic Enzymes in Rats' Posterior Subcutaneous Fat Depot., PMID:39519099
Safety and efficacy of pembrolizumab, radiation therapy, and surgery versus radiation therapy and surgery for stage III soft tissue sarcoma of the extremity (SU2C-SARC032): an open-label, randomised clinical trial., PMID:39547252
High expression of malic enzyme 1 predicts adverse prognosis in patients with cytogenetically normal acute myeloid leukaemia and promotes leukaemogenesis through the IL-6/JAK2/STAT3 pathways., PMID:39610460
Multidimensional analyses identify genes of high priority for pancreatic cancer research., PMID:39774001
Characterization of mint virus C, a new member of the genus Carlavirus., PMID:39792272
Mechanistic Understanding of Differences in Cytotoxicity Induced by Food Additives Methyleugenol and Methylisoeugenol., PMID:39836452
Letetresgene Autoleucel in Advanced/Metastatic Myxoid/Round Cell Liposarcoma., PMID:39836945
JMJD6 Rewires ATF4-Dependent Glutathione Metabolism to Confer Ferroptosis Resistance in SPOP-Mutated Prostate Cancer., PMID:39903850
PHGDH inhibition and FOXO3 modulation drives PUMA-dependent apoptosis in osteosarcoma., PMID:39934141
Transcriptomic analysis of broiler chickens reveals metabolic adaptations to a reduced crude protein diet., PMID:39983527
Identification and Validation of Biomarkers in Metabolic Dysfunction-Associated Steatohepatitis Using Machine Learning and Bioinformatics., PMID:39995143
Glucose and Insulin Differently Regulate Gluconeogenic and Ureagenic Gene Expression., PMID:40024748
Transcriptomic profiling identifies ferroptosis and NF-κB signaling involved in α-dimorphecolic acid regulation of microglial inflammation., PMID:40038710
Mitochondria-organelle crosstalk in establishing compartmentalized metabolic homeostasis., PMID:40250411
Alstonia scholaris (L.) R. Br. ameliorated diabetic nephropathy through PPAR-δ pathway., PMID:40294665
Glabridin protects against paraquat-induced acute lung injury by targeting ME1 to mitigate oxidative stress, mitochondrial dysfunction, and cGAS-STING activation., PMID:40316060
Glutamine catabolism supports amino acid biosynthesis and suppresses the integrated stress response to promote photoreceptor survival., PMID:40396212
The sphingosine-1-phosphate receptor 2 S1PR2 mediates chronic glucocorticoid exposure-induced hepatic steatosis and hypertriglyceridemia., PMID:40490140
Transcriptome Analysis Reveals Co-Expression Regulation of Sugar Transport and Signaling Networks in Initiating Stolon-to-Tuber Transition in Potato., PMID:40508086
For research use only. Not for human or drug use.
