Catalog No.
YHK40301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr386-Thr529
Predicted molecular weight
18.64 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96T37
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
RBM15, RNA-binding motif protein 15, OTT1, One-twenty two protein 1, OTT, RNA-binding protein 15
Note
For research use only.
The m6A writer RBM15 drives the growth of triple-negative breast cancer cells through the stimulation of serine and glycine metabolism., PMID:38825643
RBM15 facilities lung adenocarcinoma cell progression by regulating RASSF8 stability through N6 Methyladenosine modification., PMID:38838436
RBM15-Mediated N6-Methyl Adenosine (m6A) Modification of EZH2 Drives the Epithelial-Mesenchymal Transition of Cervical Cancer., PMID:38842201
Identification of m6A modification patterns and RBM15 mediated macrophage phagocytosis in pancreatic cancer: An integrative analysis., PMID:38878830
Exploring the role of m 6 A writer RBM15 in cancer: a systematic review., PMID:38915367
RBM15 Protects From Myocardial Infarction by Stabilizing NAE1., PMID:38984049
N6-methyladenosine-mediated LINC01087 promotes lung adenocarcinoma progression by regulating miR-514a-3p to upregulate centrosome protein 55., PMID:39023191
Epigenetic mechanism of RBM15 in affecting cisplatin resistance in laryngeal carcinoma cells by regulating ferroptosis., PMID:39039611
m6A modification of VEGFA mRNA by RBM15/YTHDF2/IGF2BP3 contributes to angiogenesis of hepatocellular carcinoma., PMID:39092767
RBM15 activates glycolysis in M1-type macrophages to promote the progression of aortic aneurysm and dissection., PMID:39113895
Identification of RBM15 as a prognostic biomarker in prostate cancer involving the regulation of prognostic m6A-related lncRNAs., PMID:39118157
Bioinformatics analysis and validation of RNA methylation-related genes in osteogenic and adipogenic differentiation of rat bone marrow mesenchymal stem cells., PMID:39181069
RBM15 Promotes High Glucose-Induced Lens Epithelial Cell Injury by Inducing PRNP N6-Methyladenine Modification During Diabetic Cataract., PMID:39206850
Structures and mechanisms of the RNA m 6A writer., PMID:39238441
TARGET based m6A methylation-related genes predict prognosis relapsed B-cell acute lymphoblastic leukemia., PMID:39251964
RBM15B Promotes Prostate Cancer Cell Proliferation via PCNA m6A Modification., PMID:39361104
RNA methylase RBM15 facilitates malignant progression of colorectal cancer through regulating E2F2 in an m6A modification-dependent manner., PMID:39403943
RBM15 drives the progression of lung adenocarcinoma by regulating N6-methyladenosine-mediated LDHA mRNA stability., PMID:39406308
RBM15 Drives Breast Cancer Cell Progression and Immune Escape via m6A-Dependent Stabilization of KPNA2 mRNA., PMID:39488447
RBM15-mediated the m6A modification of MAT2A promotes osteosarcoma cell proliferation, metastasis and suppresses ferroptosis., PMID:39527319
RBM15 facilitates osimertinib resistance of lung adenocarcinoma through m6A-dependent epigenetic silencing of SPOCK1., PMID:39528815
RBM15 promotes lipogenesis and malignancy in gastric cancer by regulating N6-Methyladenosine modification of ACLY mRNA in an IGF2BP2-dependent manner., PMID:39549859
RBM15 increase tumor-infiltrating CD4+ T cell in ESCC via modulating of PLOD3., PMID:39659928
Mechanism of RBM15 in the malignant proliferation of colorectal cancer cells through regulating the stability of LncRNA FGD5-AS1 via m6A modification., PMID:39701357
The role of m6A methylation genes in predicting poor prognosis in sepsis: identifying key biomarkers and therapeutic targets., PMID:39702336
MLL1 promotes placental trophoblast ferroptosis and aggravates preeclampsia symptoms through epigenetic regulation of RBM15/TRIM72/ADAM9 axis., PMID:39709463
RBM15-dependent m6A modification mediates progression of non-small cell lung cancer cells., PMID:39716068
The changes in the ratio of Dicer1 transcripts can participate in the neuronal hypoxic response by regulating miR-29b., PMID:39756430
m6A Methylation Regulator RBM15-Mediated Upregulation of ITGBL1 mRNA Stability Aggravates Colon Adenocarcinoma Progression by Remodeling the Tumor Microenvironment., PMID:39840822
RBM15-mediated m6A modification of XPR1 promotes the malignant progression of lung adenocarcinoma., PMID:39928150
RBM15 recruits myeloid-derived suppressor cells via the m6A-IGF2BP3/CBR3-AS1/miR-409-3p/CXCL1 axis, facilitating radioresistance in non-small-cell lung cancer., PMID:39962467
A m6A writer RBM15 enhances the cell malignancy of osteosarcoma by mediating m6A modification of lncRNA THAP9-AS1., PMID:40015502
RBM15 relies on m6A modification to inhibit UBE2C, alleviating hippocampal neuronal injury by limiting microglial inflammation., PMID:40049430
Clinical Significance of RBM15 in Gastric Cancer: A Multi-Database Validation., PMID:40051357
RBM15-MKL1 fusion protein promotes leukemia via m6A methylation and WNT pathway activation., PMID:40060447
N6-methyladenosine methyltransferase Wilms tumor 1-associated protein impedes diabetic wound healing through epigenetically activating DNA methyltransferase 1., PMID:40093271
The m6A modification of SOX18 leads to increased PTX3 and cardiomyocyte pyroptosis in sepsis-induced cardiomyopathy., PMID:40093897
RBM15, an m6A enzyme, suppresses NLRP3 inflammasome activation in rheumatoid arthritis through macrophage metabolism., PMID:40095631
Lactylation increases the stability of RBM15 to drives m6A modification in non-small-cell lung cancer cells., PMID:40135634
Irradiation of 125I seeds blocks glycolysis in pancreatic cancer by inhibiting KLF5 m6A methylation through the suppression of RBM15., PMID:40147709
Exploration of mRNA-modifying METTL3 oncogene as momentous prognostic biomarker responsible for colorectal cancer development., PMID:40177651
Hepatitis B Virus Promotes Angiogenesis in Hepatocellular Carcinoma by Increasing m6A Modification of VEGFA mRNA via IGF2BP3., PMID:40260505
RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer., PMID:40370450
lncSLERT Promotes Liver Metastasis in Colorectal Cancer by Down-Regulating HUNK Expression via RBM15-Mediated m6A Modification., PMID:40371234
Role of N6-methyladenosine methyltransferase component RBM15 in cancer progression and its therapeutic potential., PMID:40402374
Integration of bioinformatics and identification of the role of m6A genes in NAFLD., PMID:40435202
RBM15-MKL1 fusion protein promotes leukemia via m6A methylation and WNT pathway activation., PMID:40435410
CRISPR screen decodes SWI/SNF chromatin remodeling complex assembly., PMID:40447637
RBM15 promotes m6A methylation and stability of KLF6 mRNA to accelerate pyroptosis of retinal ganglion cells in early-stage diabetic retinopathy., PMID:40464812
METTL3-mediated SNHG1 m6A modification promotes proliferation and migration through transcriptional regulation of WDR74 in osteosarcoma., PMID:40510136
For research use only. Not for human or drug use.
