Catalog No.
PHC23701
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human GPX1 (Thr50-Ala202).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Cellular glutathione peroxidase,Glutathione peroxidase 1,GPx-1,GPX1,GSHPx-1
Purification
Purified by antigen affinity column.
Accession
P07203
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Transcriptomic signatures in peripheral CD4+T-lymphocytes may reflect melanoma staging and immunotherapy responsiveness prior to ICI initiation., PMID:40226614
Distribution of glutathione peroxidase-1 immunoreactive cells in pancreatic islets from type 1 diabetic donors and non-diabetic donors with and without islet cell autoantibodies is variable and independent of disease., PMID:40059238
Benzo (A) pyrene exposure alters alveolar epithelial and macrophage cells diversity and induces antioxidant responses in lungs., PMID:39506978
Potential benefits of advanced chelate-based trace minerals in improving bone mineralization, antioxidant status, immunity, and gene expression modulation in heat-stressed broilers., PMID:39356694
Bisphenol A-induced oxidative stress increases the production of ovarian cancer stem cells in mice., PMID:39322090
Dietary Artemisia arborescens Supplementation Effects on Growth, Oxidative Status, and Immunity of Gilthead Seabream (Sparus aurata L.)., PMID:38672308
Selective elimination of younger erythrocytes in blood circulation and associated molecular changes in benzo (a) pyrene induced mouse model of lung cancer., PMID:38178996
Immunohistochemical Expression of Glutathione Peroxidase 1 (Gpx-1) as an Independent Prognostic Factor in Colon Adenocarcinoma Patients., PMID:37242524
Involvements of Nrf2 and oxidative stress in the ozone-elicited exacerbation in an allergic rhinitis model., PMID:36965277
Effects of aflatoxin B1 on growth performance, antioxidant status, immune response, and pro-inflammatory cytokine mRNA expression in ISA chicks., PMID:36176699
Could allicin alleviate trastuzumab-induced cardiotoxicity in a rat model through antioxidant, anti-inflammatory, and antihyperlipidemic properties?, PMID:35605695
Nephronectin influences EAE development by regulating the Th17/Treg balance via reactive oxygen species., PMID:35235429
Pterocarpus santalinus L. extract mitigates gamma radiation-inflicted derangements in BALB/c mice by Nrf2 upregulation., PMID:34146850
System Genetics Including Causal Inference Identify Immune Targets for Coronary Artery Disease and the Lifespan., PMID:33625251
[Study of selenomethionine on the selenoproteins expression in hepatocyte L02 and the synergistic effect of serine]., PMID:33517969
Study on antioxidant effect of recombinant glutathione peroxidase 1., PMID:33383079
Potential relationship between the selenoproteome and cancer., PMID:33133596
Selenium Regulation of the Immune Function of Dendritic Cells in Mice Through the ERK, Akt and RhoA/ROCK Pathways., PMID:33107016
Reduction of endoglin receptor impairs mononuclear cell-migration., PMID:32954380
Validation and identification of reference genes in Chinese hamster ovary cells for Fc-fusion protein production., PMID:32216463
Dexamethasone and Tofacitinib suppress NADPH oxidase expression and alleviate very-early-onset ileocolitis in mice deficient in GSH peroxidase 1 and 2., PMID:31689440
Glutathione Peroxidase 1 Promotes NSCLC Resistance to Cisplatin via ROS-Induced Activation of PI3K/AKT Pathway., PMID:31032363
Gliclazide reduced oxidative stress, inflammation, and bone loss in an experimental periodontal disease model., PMID:30810635
GPX1 Localizes to the Nucleus in Prostate Epithelium and its Levels are not Associated with Prostate Cancer Recurrence., PMID:30453672
VEGF-B is a potent antioxidant., PMID:30249667
Distribution of oxidized DJ-1 in Parkinson's disease-related sites in the brain and in the peripheral tissues: effects of aging and a neurotoxin., PMID:30104666
Effects of plant essential oil supplementation on growth performance, immune function and antioxidant activities in weaned pigs., PMID:29903022
Breast Cancer Cell Apoptosis is Synergistically Induced by Curcumin, Trastuzumab, and Glutathione Peroxidase-1 but Robustly Inhibited by Glial Cell Line-Derived Neurotrophic Factor., PMID:29297700
Anti-CD47 monoclonal antibody therapy reduces ischemia-reperfusion injury of renal allografts in a porcine model of donation after cardiac death., PMID:29087049
Altered expression of mitochondrial antioxidants in oral squamous cell carcinoma., PMID:28904321
Impaired redox environment modulates cardiogenic and ion-channel gene expression in cardiac-resident and non-resident mesenchymal stem cells., PMID:28092181
Porcine GPX1 enhances GP5-based DNA vaccination against porcine reproductive and respiratory syndrome virus., PMID:28063474
Abrogation of Nrf2 impairs antioxidant signaling and promotes atrial hypertrophy in response to high-intensity exercise stress., PMID:27048381
Molecular optimization of rabies virus glycoprotein expression in Pichia pastoris., PMID:26880068
Selenium Alleviates Aflatoxin B₁-Induced Immune Toxicity through Improving Glutathione Peroxidase 1 and Selenoprotein S Expression in Primary Porcine Splenocytes., PMID:26806088
Threonine modulates immune response, antioxidant status and gene expressions of antioxidant enzymes and antioxidant-immune-cytokine-related signaling molecules in juvenile blunt snout bream (Megalobrama amblycephala)., PMID:26631806
Effect of Selenium Supplementation on Redox Status of the Aortic Wall in Young Spontaneously Hypertensive Rats., PMID:26473024
Effects of Selenium Supplementation on Spontaneous Autoimmune Thyroiditis in NOD.H-2h4 Mice., PMID:26121912
ω-3 PUFA rich camelina oil by-products improve the systemic metabolism and spleen cell functions in fattening pigs., PMID:25303320
Identification of differential proteins in colorectal cancer cells treated with caffeic acid phenethyl ester., PMID:25206290
Increased 8-hydroxy-2'-deoxyguanosine in plasma and decreased mRNA expression of human 8-oxoguanine DNA glycosylase 1, anti-oxidant enzymes, mitochondrial biogenesis-related proteins and glycolytic enzymes in leucocytes in patients with systemic lupus erythematosus., PMID:24345202
Sublethal oxidative stress induces the premature senescence of human mesenchymal stem cells derived from endometrium., PMID:24062878
Impact of glutathione peroxidase-1 deficiency on macrophage foam cell formation and proliferation: implications for atherogenesis., PMID:23991041
Resistin and visfatin in steatotic and non-steatotic livers in the setting of partial hepatectomy under ischemia-reperfusion., PMID:23968888
Role for granulocyte colony stimulating factor in angiotensin II-induced neutrophil recruitment and cardiac fibrosis in mice., PMID:23761490
Endosomal NADPH-oxidase is critical for induction of the tissue factor gene in monocytes and endothelial cells. Lessons from the antiphospholipid syndrome., PMID:23328933
Localization and regulation of pancreatic selenoprotein P., PMID:23125459
Evidences for a role of glutathione peroxidase 4 (GPx4) in methylmercury induced neurotoxicity in vivo., PMID:22885222
Effects of selenium on the vessel walls and anti-elastin antibodies in spontaneously hypertensive rats., PMID:22312058
Altered gene expression in rat cranial neural crest cells exposed to a teratogenic glucose concentration in vitro: paradoxical downregulation of antioxidative defense genes., PMID:21818840
For research use only. Not for human or drug use.
