Catalog No.
YHH04701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg73-Arg256
Predicted molecular weight
23.25 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q15233
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
54 kDa nuclear RNA- and DNA-binding protein, NRB54, p54nrb, NMT55, NonO protein, p54(nrb), 55 kDa nuclear protein, NONO, DNA-binding p52/p100 complex, 52 kDa subunit, Non-POU domain-containing octamer-binding protein
Note
For research use only.
COVID-19 Is a Coronary Artery Disease Risk Equivalent and Exhibits a Genetic Interaction With ABO Blood Type., PMID:39381876
Differential Protein Expression in Extracellular Vesicles Defines Treatment Responders and Non-Responders in Multiple Sclerosis., PMID:39409091
Swine NONO promotes IRF3-mediated antiviral immune response by Detecting PRRSV N protein., PMID:39413144
The roles of blood picture, haemoglobinopathy traits, and blood groups determined in routine antenatal tests in the screening for complications in pregnancy., PMID:39433460
Aggregation of human plasma and of human blood induced in vitro by pegfilgrastim originator formulation buffer and pegfilgrastim products., PMID:39492447
Cellular NONO protein binds to the flavivirus replication complex and promotes positive-strand RNA synthesis., PMID:39499073
LncRNA GClnc1 promotes osteosarcoma progression by stabilizing NONO and blocking FBXW7-mediated ubiquitination., PMID:39523321
TFE3 -rearranged Head and Neck Neoplasms : Twenty-two Cases Spanning the Morphologic Continuum Between Alveolar Soft Part Sarcoma and PEComa and Highlighting Genotypic Diversity., PMID:39593216
Factors Influencing Nerinetide Effect on Infarct Volume in Patients Without Alteplase in the Randomized ESCAPE-NA1 Trial., PMID:39648909
A novel nuclear RNA HSD52 scaffolding NONO/SFPQ complex modulates DNA damage repair to facilitate temozolomide resistance., PMID:39673809
Examining the potential involvement of NONO in TDP-43 proteinopathy in Drosophila., PMID:39690447
CPNE7 promotes colorectal tumorigenesis by interacting with NONO to initiate ZFP42 transcription., PMID:39695095
Structural plasticity of the coiled-coil interactions in human SFPQ., PMID:39698821
NONO-related X-linked intellectual disability syndrome: Further clinical and molecular delineation., PMID:39709004
Genotype-by-Environment Effects of Cis-Variations in the Atgl Promoter Mediate the Divergent Pattern of Phenotypic Plasticity for Temperature Adaptation in Two Congeneric Oyster Species., PMID:39718158
YY1 drives PARP1 expression essential for PARylation of NONO in mRNA maturation during neuroblastoma progression., PMID:39731187
A Transition From Interindividual Uniformity to Diversity in Appearance and Transcriptional Features at Midlife in Caenorhabditis elegans., PMID:39743742
Recombinant Human Tissue Kallikrein-1 for Treating Acute Ischemic Stroke and Preventing Recurrence., PMID:39758014
Proteins Associated with Neurodegenerative Diseases: Link to DNA Repair., PMID:39767715
ABO and RhD blood groups as contributors to dyslipidaemia - a cross-sectional study., PMID:39844181
Salvianolic acid B drives gluconeogenesis and peroxisomal redox remodeling in cardiac ischemia/reperfusion injury: A metabolism regulation by metabolite signal crosstalk., PMID:39855316
CircMETTL6 Suppresses Ovarian Cancer Cell Growth and Metastasis Through Inhibition of GDF15 Transcription by Disrupting the NONO-POLR2A Complex., PMID:39899667
The Investigation of the Distribution of ABO/Rh Blood Group in Hospitalized COVID-19 Patients and Its Association With Disease Severity, Clinical Outcomes, Lab Tests, and Radiologic Findings., PMID:39931255
Efficacy and safety of nerinetide in acute ischaemic stroke in patients undergoing endovascular thrombectomy without previous thrombolysis (ESCAPE-NEXT): a multicentre, double-blind, randomised controlled trial., PMID:39955119
Histo-blood group ABO system transferase plasma levels and risk of future venous thromboembolism: the HUNT study., PMID:40009491
Meg3-NONO-RAR axis mediates RA pathway activation in TCDD-induced cleft palate., PMID:40024514
NONO regulates m5C modification and alternative splicing of PTEN mRNAs to drive gastric cancer progression., PMID:40033337
Melanophilin inhibit the growth and lymph node metastasis of triple negative breast cancer via the NONO-SPHK1-S1P axis., PMID:40050909
Prevalence of katG and inhA mutations associated with isoniazid resistance in Mycobacterium tuberculosis clinical isolates in Cameroon., PMID:40059193
NONO interacts with nuclear PKM2 and directs histone H3 phosphorylation to promote triple-negative breast cancer metastasis., PMID:40059196
ABO blood group system correlates with preoperative serum PSA level in patients with prostate cancer., PMID:40075227
Reduced plasma levels of GM-CSF is a common feature of Schistosoma mansoni-infected school-aged children., PMID:40092989
The Prevalence of the Thrombotic SNPs rs6025, rs1799963, rs2066865, rs2289252 and rs8176719 in Patients with Venous Thromboembolism in the Czech Population., PMID:40094632
Safety, Functional Disability, Healthcare Utilization, and Quality-of-Life Outcomes in Elderly Receiving Alteplase and Tenecteplase: A Secondary Analysis From the AcT Trial., PMID:40123483
TFE3 fusions drive oxidative metabolism and ferroptosis resistance in translocation renal cell carcinoma., PMID:40148585
Plasma biomarkers distinguish Boston Criteria 2.0 cerebral amyloid angiopathy from healthy controls., PMID:40156276
Immiscible proteins compete for RNA binding to order condensate layers., PMID:40166346
The metabolic enzyme GYS1 condenses with NONO/p54nrb in the nucleus and spatiotemporally regulates glycogenesis and myogenic differentiation., PMID:40200092
TFE3 fusion oncoprotein condensates drive transcriptional reprogramming and cancer progression in translocation renal cell carcinoma., PMID:40222010
DNMT1 is required for efficient DSB repair and maintenance of replication fork stability, and its loss reverses resistance to PARP inhibitors in cancer cells., PMID:40234721
Exosomal Biglycan promotes gastric cancer progression via M2 polarization and CXCL10-mediated JAK/STAT1 activation., PMID:40311912
Enhancer-Associated LncRNA-ITGA2 Promotes Vascular Remodeling Through ITGA2., PMID:40321134
Blood group O attributes to prolonged progression-free survival, overall survival, and 5-year survival in isocitrate dehydrogenase-wildtype glioblastoma patients with MGMT promoter methylation., PMID:40351837
The NONO protein regulates nonclassical DNA structure: Effects on circadian genes and DNA damage., PMID:40352720
Association between maternal ABO blood group and preeclampsia: a prospective cohort study., PMID:40353138
O-GlcNAcylation of NONO regulates paraspeckle component assembly and contributes to colon cancer cell proliferation., PMID:40360465
Firre facilitates myocardial repair by inducing cardiomyocyte cell cycle activity through PTBP1 binding and Akt activation., PMID:40378620
Evaluation of 3,606 renal cell tumors for TFE3 rearrangements and TFEB alterations via fluorescence in situ hybridization, next generation sequencing, and GPNMB immunohistochemistry., PMID:40381702
KHSRP promotes the malignant behavior and cisplatin resistance of bladder cancer cells through the CLASP2/MAPRE1 axis., PMID:40382315
Selected cell receptor genotypes differentially modulate the ABO blood group influence on Factor VIII levels in severe aortic stenosis., PMID:40398046
For research use only. Not for human or drug use.
