Catalog No.
YHE54001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg104-Gly274
Predicted molecular weight
21.02 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P47985
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Rieske iron-sulfur protein, UQCRFS1 mitochondrial targeting sequence, UQCRFS1, Ubiquinol-cytochrome c reductase 8 kDa protein, Cytochrome b-c1 complex subunit 11, Subunit 9, Su9, RISP, Rieske protein UQCRFS1, Cytochrome b-c1 complex subunit 5, Complex III subunit 5, 8 kDa subunit 9, Ubiquinol-cytochrome c reductase iron-sulfur subunit, UQCRFS1 MTS, Complex III subunit IX, Cytochrome b-c1 complex subunit Rieske, mitochondrial
Note
For research use only.
Impaired OXPHOS complex III in breast cancer., PMID:21901141
Ribonucleoprotein Y-box-binding protein-1 regulates mitochondrial oxidative phosphorylation (OXPHOS) protein expression after serum stimulation through binding to OXPHOS mRNA., PMID:22280412
Zinc-finger protein 331, a novel putative tumor suppressor, suppresses growth and invasiveness of gastric cancer., PMID:22370639
Functional characterization of the 19q12 amplicon in grade III breast cancers., PMID:22433433
Amplification of the UQCRFS1 Gene in Gastric Cancers., PMID:22792519
LYRM7/MZM1L is a UQCRFS1 chaperone involved in the last steps of mitochondrial Complex III assembly in human cells., PMID:23168492
Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling., PMID:23415911
Protein biomarkers of susceptibility and resilience to stress in a rat model of depression., PMID:27105822
Co-expressed differentially expressed genes and long non-coding RNAs involved in the celecoxib treatment of gastric cancer: An RNA sequencing analysis., PMID:27698747
Systematic expression analysis of the mitochondrial complex III subunits identifies UQCRC1 as biomarker in clear cell renal cell carcinoma., PMID:27845902
A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III., PMID:28380382
TTC19 Plays a Husbandry Role on UQCRFS1 Turnover in the Biogenesis of Mitochondrial Respiratory Complex III., PMID:28673544
Mitochondrial UQCRB as a new molecular prognostic biomarker of human colorectal cancer., PMID:29147009
Mitochondrial complex III Rieske Fe-S protein processing and assembly., PMID:29243944
Analysis of Housekeeping Genes for Accurate Normalization of qPCR Data During Early Postnatal Brain Development., PMID:29492861
mRNA-binding protein tristetraprolin is essential for cardiac response to iron deficiency by regulating mitochondrial function., PMID:29915044
Withaferin A-mediated apoptosis in breast cancer cells is associated with alterations in mitochondrial dynamics., PMID:30685490
Bi-Allelic UQCRFS1 Variants Are Associated with Mitochondrial Complex III Deficiency, Cardiomyopathy, and Alopecia Totalis., PMID:31883641
Pulse-chase SILAC-based analyses reveal selective oversynthesis and rapid turnover of mitochondrial protein components of respiratory complexes., PMID:31974161
Distinct Roles of Mitochondrial HIGD1A and HIGD2A in Respiratory Complex and Supercomplex Biogenesis., PMID:32375044
The diabetes medication canagliflozin promotes mitochondrial remodelling of adipocyte via the AMPK-Sirt1-Pgc-1α signalling pathway., PMID:32835596
Hypoxia Promotes Mitochondrial Complex I Abundance via HIF-1α in Complex III and Complex IV Eficient Cells., PMID:33003371
SIRT6 enhances oxidative phosphorylation in breast cancer and promotes mammary tumorigenesis in mice., PMID:33482921
Mitochondrial metabolism is essential for invariant natural killer T cell development and function., PMID:33753493
Tetramethylpyrazine Improves Cognitive Impairment and Modifies the Hippocampal Proteome in Two Mouse Models of Alzheimer's Disease., PMID:33791294
Homozygous missense mutation in UQCRC2 associated with severe encephalomyopathy, mitochondrial complex III assembly defect and activation of mitochondrial protein quality control., PMID:33865955
Integrated Proteomics and Transcriptomics Analyses Reveals the Possible Antifungal Mechanism of an Indoloquinoline Alkaloid Neocryptolepine against Rhizoctonia solani., PMID:34075744
Reperfusion mediates heme impairment with increased protein cysteine sulfonation of mitochondrial complex III in the post-ischemic heart., PMID:34331972
GNAi2/gip2-Regulated Transcriptome and Its Therapeutic Significance in Ovarian Cancer., PMID:34439877
Identification of Hub Genes Associated With Tuberculous Pleurisy by Integrated Bioinformatics Analysis., PMID:34925441
Integrated analysis of transcriptome profiling of lncRNAs and mRNAs in livers of type 2 diabetes mellitus., PMID:35073196
Identifying Potential Mitochondrial Proteome Signatures Associated with the Pathogenesis of Pulmonary Arterial Hypertension in the Rat Model., PMID:35237384
Next-Generation Sequencing analysis discloses genes implicated in equine endometrosis that may lead to tumorigenesis., PMID:35760027
Altered mitochondrial microenvironment at the spotlight of musculoskeletal aging and Alzheimer's disease., PMID:35788655
Different Approaches for the Profiling of Cancer Pathway-Related Genes in Glioblastoma Cells., PMID:36142793
Integrated Omics analysis of pig muscle metabolism under the effects of dietary Chlorella vulgaris and exogenous enzymes., PMID:36216870
Effects of short-term waterfall forest aerosol air exposure on rat lung proteomics., PMID:36544689
High-throughput proteomic characterization of seminal plasma from bulls with contrasting semen quality., PMID:36714547
LYRM7-associated mitochondrial complex III deficiency with non-cavitating leukoencephalopathy and stroke-like episodes., PMID:36757047
UQCRFS1 serves as a prognostic biomarker and promotes the progression of ovarian cancer., PMID:37221238
Exploring biomarkers of premature ovarian insufficiency based on oxford nanopore transcriptional profile and machine learning., PMID:37460774
Transcriptomics and metabolomics study in mouse kidney of the molecular mechanism underlying energy metabolism response to hypoxic stress in highland areas., PMID:37869643
The molecular mechanism of sepsis-induced diaphragm dysfunction., PMID:38249924
Proteomics analysis of differentially abundant proteins in the rohu kidney infected with Edwardsiella tarda., PMID:38430708
Mitochondria regulate proliferation in adult cardiac myocytes., PMID:38722697
Identification of potential obese-specific biomarkers and pathways associated with abdominal subcutaneous fat deposition in pig using a comprehensive bioinformatics strategy., PMID:38832038
Sex and organ specific proteomic responses to vitamin C deficiency in the brain, heart, liver, and spleen of Gulo-/- mice., PMID:39388511
Dual diagnosis of UQCRFS1-related mitochondrial complex III deficiency and recessive GJA8-related cataracts., PMID:39421685
Neuroinflammation mediates the progression of neonate hypoxia-ischemia brain damage to Alzheimer's disease: a bioinformatics and experimental study., PMID:39872979
AI-assisted multi-OMICS analysis reveals new markers for the prediction of AD., PMID:40441366
For research use only. Not for human or drug use.
