Catalog No.
YHC44001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Glu472
Predicted molecular weight
82.81 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P09913
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
P54, Interferon-induced 54 kDa protein, Interferon-induced protein with tetratricopeptide repeats 2, CIG-42, G10P2, IFI54, IFIT-2, IFI-54K, ISG-54 K, IFIT2, ISG54
Note
For research use only.
AEN Suppresses the Replication of Porcine Epidemic Diarrhea Virus by Inducing the Expression of Type I IFN and ISGs in MARC-145 Cells., PMID:38251332
Transcriptome Analysis of LLC-PK Cells Single or Coinfected with Porcine Epidemic Diarrhea Virus and Porcine Deltacoronavirus., PMID:38257774
Interferon response and profiling of interferon response genes in peripheral blood of vaccine-naive COVID-19 patients., PMID:38268924
MX1 and UBE2L6 are potential metaflammation gene targets in both diabetes and atherosclerosis., PMID:38406276
Screening of Genes Associated with Immune Infiltration of Discoid Lupus Erythematosus Based on Weighted Gene Co-expression Network Analysis., PMID:38451400
Label-free quantitative proteomics reveals the mechanisms of Aurora kinase B in renal cell carcinoma., PMID:38516642
Effects of Dietary l-Glutamine Supplementation on the Intestinal Function and Muscle Growth of Piglets., PMID:38541729
[Investigation of the immune profile of multiple myeloma patients achieving long-term survival after autologous stem cell transplantation]., PMID:38561281
Enteric coronavirus nsp2 is a virulence determinant that recruits NBR1 for autophagic targeting of TBK1 to diminish the innate immune response., PMID:38597182
Enhanced GATA4 expression in senescent systemic lupus erythematosus monocytes promotes high levels of IFNα production., PMID:38605949
Decreased Expression of PLD2 Promotes EMT in Colorectal Cancer Invasion and Metastasis., PMID:38706911
A bioinformatics approach to systematically analyze the molecular patterns of monkeypox virus-host cell interactions., PMID:38737277
Discovery of Potential Drug Targeting Key Genes in Alzheimer's Disease: Insights from Transcriptome Analysis and Molecular Docking., PMID:38802701
Type I interferon signaling promotes radioresistance in head and neck cancer., PMID:38881922
The Role of Interferon-Induced Proteins with Tetratricopeptide Repeats 1 and 2 in Sepsis-Induced Acute Liver Injury., PMID:38882652
The interferon-induced protein, IFIT2, requires RNA-binding activity and neuronal expression to protect mice from intranasal vesicular stomatitis virus infection., PMID:38888342
Predicting human and viral protein variants affecting COVID-19 susceptibility and repurposing therapeutics., PMID:38902252
A comparative analysis of RNA-Seq and NanoString technologies in deciphering viral infection response in upper airway lung organoids., PMID:38957806
Expression of ISG60 is induced by TLR3 signaling in BEAS‑2B bronchial epithelial cells: Possible involvement in CXCL10 expression., PMID:38963029
Cap-related modifications of RNA regulate binding to IFIT proteins., PMID:39009378
RNAseq of Gingival Fibroblasts Exposed to PRF Membrane Lysates and PRF Serum., PMID:39120336
Immune horses rapidly increase antileukoproteinase and lack type I interferon secretion during mucosal innate immune responses against equine herpesvirus type 1., PMID:39162558
Immunological landscape of human lymphoid explants during measles virus infection., PMID:39253971
IFIT2 mediates iron retention and cholesterol efflux in atherosclerosis., PMID:39276454
Genome-wide analysis reveals the MORC3-mediated repression of PD-L1 expression in head and neck cancer., PMID:39329063
Varicella-zoster virus recapitulates its immune evasive behaviour in matured hiPSC-derived neurospheroids., PMID:39351233
Exploration of the link between COVID-19 and gastric cancer from the perspective of bioinformatics and systems biology., PMID:39371335
Metabolic dysfunction-associated steatohepatitis reduces interferon and macrophage liver gene signatures in patients with chronic hepatitis B., PMID:39490745
Exploration of common pathogenesis and candidate hub genes between HIV and monkeypox co-infection using bioinformatics and machine learning., PMID:39496786
α7-Nicotinic Acetylcholine Receptor Activation Modulates BV2 Microglial Plasticity via miR-21/TNF-α/NFκB in Oxygen-Glucose Deprivation/Reoxygenation., PMID:39718716
Unveiling Key Biomarkers and Mechanisms in Septic Cardiomyopathy: A Comprehensive Transcriptome Analysis., PMID:39735900
PJA2 Suppresses Colorectal Cancer Progression by Controlling HDAC2 Degradation and Stability., PMID:39928532
SARS-CoV-2 S, M, and E Structural Glycoproteins Differentially Modulate Endoplasmic Reticulum Stress Responses., PMID:39940816
Robust antiviral innate immune response and miRNA regulatory network were identified in ZIKV-infected cells: implications in the pathogenesis of ZIKV infection., PMID:39955676
HOXD10: A novel gene implicated in human Müllerian duct anomalies., PMID:39987682
Short 5' UTRs serve as a marker for viral mRNA translation inhibition by the IFIT2-IFIT3 antiviral complex., PMID:39990370
Neutrophils Display Novel Partners of Cytosolic Proliferating Cell Nuclear Antigen Involved in Interferon Response in COVID-19 Patients., PMID:40015257
IFIT3 RNA-binding activity promotes influenza A virus infection and translation efficiency., PMID:40027740
Sequence Diversity in the 3' Untranslated Region of Alphavirus Modulates IFIT2-Dependent Restriction in a Cell Type-Dependent Manner., PMID:40079162
Mouse models of Tembusu virus infection for differentiating between cluster 2.1 and 2.2 isolates., PMID:40101376
Immunomodulatory roles of autophagic flux and IFIT in human ectocervical cells upon Trichomonas vaginalis infection., PMID:40220619
The first trimester human placenta responds to Zika virus infection inducing an interferon (IFN) and antiviral interferon stimulated gene (ISG) response., PMID:40253335
Type I IFN receptor blockade alleviates liver fibrosis through macrophage-derived STAT3 signaling., PMID:40260261
Correlation Analysis Between IFIT2 and HLA Class II in Oral Cancer., PMID:40295076
Comprehensive bioinformatics analysis uncover molecular pathways shared between osteoarthritis and atherosclerosis., PMID:40335993
Unveiling EXOC4/SEC8: a key player in enhancing antiviral immunity by inhibiting the FBXL19-STING1-SQSTM1 signaling axis., PMID:40413753
IFIT2-induced transcriptomic changes in Mycobacterium tuberculosis infected macrophages., PMID:40463504
IFIT3 RNA-binding activity promotes influenza A virus infection and translation efficiency., PMID:40497724
Differentially expressed ncRNAs as key regulators in infection of human bronchial epithelial cells by the SARS-CoV-2 Delta variant., PMID:40510596
FKBP5 promotes osteogenic differentiation of mesenchymal stem cells through type-I interferon pathway Inhibition., PMID:40515831
For research use only. Not for human or drug use.
