Catalog No.
YHC20301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr60-Ser528
Predicted molecular weight
52.91 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P06576
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ATPSB, ATP synthase F1 subunit beta, ATP5F1B, ATP5B, ATPMB, ATP synthase subunit beta, mitochondrial
Note
For research use only.
ATP5B and ETFB metabolic markers in children with congenital hydronephrosis., PMID:27840937
Possible Involvement of F1F0-ATP synthase and Intracellular ATP in Keratinocyte Differentiation in normal skin and skin lesions., PMID:28209970
Ectopic expression of the ATP synthase β subunit on the membrane of PC-3M cells supports its potential role in prostate cancer metastasis., PMID:28259978
Comparative proteomics-network analysis of proteins responsible for ursolic acid-induced cytotoxicity in colorectal cancer cells., PMID:28347227
ATP synthase β-subunit abnormality in pancreas islets of rats with polycystic ovary syndrome and type 2 diabetes mellitus., PMID:28397049
Ca2+ binding to F-ATP synthase β subunit triggers the mitochondrial permeability transition., PMID:28507163
The role of formation of pyrrole-ATP synthase subunit beta adduct in pyrrolizidine alkaloid-induced hepatotoxicity., PMID:30244272
ATP Synthase Subunit Beta Immunostaining is Reduced in the Sclerotic Hippocampus of Epilepsy Patients., PMID:30539418
Ectopic ATP synthase β subunit proteins on human leukemia cell surface interact with platelets by binding glycoprotein IIb., PMID:30733262
Profiling of rotavirus 3'UTR-binding proteins reveals the ATP synthase subunit ATP5B as a host factor that supports late-stage virus replication., PMID:30770472
LRRK2 mutations impair depolarization-induced mitophagy through inhibition of mitochondrial accumulation of RAB10., PMID:30945962
A novel RNA aptamer identifies plasma membrane ATP synthase beta subunit as an early marker and therapeutic target in aggressive cancer., PMID:31006104
miR-450a Acts as a Tumor Suppressor in Ovarian Cancer by Regulating Energy Metabolism., PMID:31101765
Mitotane induces mitochondrial membrane depolarization and apoptosis in thyroid cancer cells., PMID:31115496
Parkinson's disease protein DJ-1 regulates ATP synthase protein components to increase neuronal process outgrowth., PMID:31197129
Acquired Resistance to HER2-Targeted Therapies Creates Vulnerability to ATP Synthase Inhibition., PMID:31690671
Mitochondrial Oxidative Phosphorylation Complex Regulates NLRP3 Inflammasome Activation and Predicts Patient Survival in Nasopharyngeal Carcinoma., PMID:31723016
Selection of reference genes for quantitative studies in acute myeloid leukaemia., PMID:31901916
Social isolation stress-resilient rats reveal energy shift from glycolysis to oxidative phosphorylation in hippocampal nonsynaptic mitochondria., PMID:32416165
Live imaging of intra-lysosome pH in cell lines and primary neuronal culture using a novel genetically encoded biosensor., PMID:32515674
Identification and validation of suitable reference genes for quantitative real-time PCR gene expression analysis in pregnant human myometrium., PMID:33386589
Novel Functions of CD147 in the Mitochondria Exacerbates Melanoma Metastasis., PMID:33390850
Characterization of the interactome of c-Src within the mitochondrial matrix by proximity-dependent biotin identification., PMID:33412331
ATP5B promotes the metastasis and growth of gastric cancer by activating the FAK/AKT/MMP2 pathway., PMID:33715234
The function of Cav-1 in MDA-MB-231 breast cancer cell migration and invasion induced by ectopic ATP5B., PMID:34009483
Effects of Three-Month Administration of High-Saturated Fat Diet and High-Polyunsaturated Fat Diets with Different Linoleic Acid (LA, C18:2n-6) to α-Linolenic Acid (ALA, C18:3n-3) Ratio on the Mouse Liver Proteome., PMID:34063343
Translational Proteomics Analysis of Anthracycline-Induced Cardiotoxicity From Cardiac Microtissues to Human Heart Biopsies., PMID:34211507
Steroid receptor RNA activator gene footprint in the progression and drug resistance of colorectal cancer through oxidative phosphorylation pathway., PMID:34520769
Proteomic dissection of large extracellular vesicle surfaceome unravels interactive surface platform., PMID:34817906
Maternal Isocaloric High-Fat Diet Induces Liver Mitochondria Maladaptations and Homeostatic Disturbances Intensifying Mitochondria Damage in Response to Fructose Intake in Adult Male Rat Offspring., PMID:35175665
Weighted Single-Step GWAS Identifies Genes Influencing Fillet Color in Rainbow Trout., PMID:35893068
TOLLIP-mediated autophagic degradation pathway links the VCP-TMEM63A-DERL1 signaling axis to triple-negative breast cancer progression., PMID:35920704
Congenital Hypermetabolism and Uncoupled Oxidative Phosphorylation., PMID:36239646
Proteomics Unveils Post-Mortem Changes in Beef Muscle Proteins and Provides Insight into Variations in Meat Quality Traits of Crossbred Young Steers and Heifers Raised in Feedlot., PMID:36293120
Synthetic antibody-derived immunopeptide provides neuroprotection in glaucoma through molecular interaction with retinal protein histone H3.1., PMID:36313990
Proteomics-based molecular and functional characteristic profiling of muscle tissue in Triploid crucian carp., PMID:36349986
Mitochondrial iron overload mediated by cooperative transfer of plasma membrane ATP5B and TFR2 to mitochondria triggers hepatic insulin resistance under PFOS exposure., PMID:36801541
Variants in ATP5F1B are associated with dominantly inherited dystonia., PMID:36860166
Aurora kinase A/AURKA functionally interacts with the mitochondrial ATP synthase to regulate energy metabolism and cell death., PMID:37386025
The impact of multifunctional enkephalin analogs and morphine on the protein changes in crude membrane fractions isolated from the rat brain cortex and hippocampus., PMID:38307418
Dramatic genome-wide reprogramming of mRNA in hypometabolic muscle., PMID:38355035
Prefrontal cortical synaptoproteome profile combined with machine learning predicts resilience towards chronic social isolation in rats., PMID:38412784
Antiviral Shrimp lncRNA06 Possesses Anti-Tumor Activity by Inducing Apoptosis of Human Gastric Cancer Stem Cells in a Cross-Species Manner., PMID:38786611
Integrated analysis of muscle transcriptome, miRNA, and proteome of Chinese indigenous breed Ningxiang pig in three developmental stages., PMID:38808333
Bioinformatic analysis of hippocampal histopathology in Alzheimer's disease and the therapeutic effects of active components of traditional Chinese medicine., PMID:39221152
Mitochondrial proteins as therapeutic targets in diabetic ketoacidosis: evidence from Mendelian randomization analysis., PMID:39469619
Chimeric SFT2D2-TBX19 Promotes Prostate Cancer Progression by Encoding TBX19-202 Protein and Stabilizing Mitochondrial ATP Synthase through ATP5F1A Phosphorylation., PMID:39540264
Exploring α-synuclein Interaction Partners and their Potential Clinical Implications for Parkinson's Disease., PMID:39560845
Causal relationship between mitochondrial function and delirium: a bidirectional two-sample Mendelian randomisation analysis., PMID:39658369
AI-assisted multi-OMICS analysis reveals new markers for the prediction of AD., PMID:40441366