Catalog No.
YHG79901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg132-Asn251
Predicted molecular weight
27.85 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q14444
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GPI-anchored protein p137, Cytoplasmic activation- and proliferation-associated protein 1, p137GPI, RNG105, M11S1, Caprin-1, Cell cycle-associated protein 1, RNA granule protein 105, CAPRIN1, GPIP137, GPI-anchored membrane protein 1, GPI-p137, GPIAP1, Membrane component chromosome 11 surface marker 1
Radiopharmaceutical application of TRK-950, an anti-CAPRIN-1 therapeutic antibody., PMID:40473914
β-propeller protein-associated neurodegeneration protein WDR45 regulates stress granule disassembly via phase separation with Caprin-1., PMID:40473629
Mitochondria-derived dsRNA-induced stress granules promote IRF3-mediated fibrotic responses., PMID:40463009
Determining the Role of Electrostatics in the Making and Breaking of the Caprin1-ATP Nanocondensate., PMID:40314620
CAPRIN1/TYMS/MTHFD2 axis promotes EMT process in nasopharyngeal carcinoma development., PMID:40246062
Development and validation of an antidrug antibody assay for TRK-950 using Melon™ gel and SPEAD pretreatment., PMID:40243353
Sequence rules for a long SPOP-binding degron required for protein ubiquitylation., PMID:40178506
Derivation of the IGGi006-A stem cell line from a patient with CAPRIN1 haploinsufficiency., PMID:40112765
Fission yeast Caprin protein is required for efficient heterochromatin establishment., PMID:40063661
Electrostatics of salt-dependent reentrant phase behaviors highlights diverse roles of ATP in biomolecular condensates., PMID:40028898
Circular RNA hsa_circ_0000288 protects against epilepsy in mice by binding to and stabilizing caprin1 protein., PMID:39962265
Multiomics analysis of O-GlcNAcylation in podocytes of diabetic kidney disease., PMID:39950214
NAT10 promotes ovarian cancer cell migration, invasion, and stemness via N4-acetylcytidine modification of CAPRIN1., PMID:39923057
CAPRIN1 Pro512Leu Variant Causes Childhood Dementia, Myoclonus-Ataxia, and Sensorimotor Neuropathy., PMID:39878554
Stress granules formation in HEI-OC1 auditory cells and in H4 human neuroglioma cells secondary to cisplatin exposure., PMID:39575153
Infection with novel duck reovirus induces stress granule and methylation-mediated host translational shutoff in Muscovy ducklings., PMID:39572728
CAPRIN1 Transcriptionally Activated PLPP4 to Inhibit DOX Sensitivity and Promote Breast Cancer Progression., PMID:39556159
Stress Granule Assembly in Pulmonary Arterial Hypertension., PMID:39513903
G3BP isoforms differentially affect stress granule assembly and gene expression during cellular stress., PMID:39356796
Atomic resolution map of the solvent interactions driving SOD1 unfolding in CAPRIN1 condensates., PMID:39172789
Structural insights into the Caprin-2 HR1 domain in canonical Wnt signaling., PMID:39159816
Can CAPRIN-1 Be Responsible for the Recurrence Potential of Odontogenic Keratocysts?, PMID:39139357
Caprin1 Bridges PRMT1 to G3BP1 and Spaces Them to Ensure Proper Stress Granule Formation., PMID:39079611
Alterations of ceramide synthesis induce PD-L1 internalization and signaling to regulate tumor metastasis and immunotherapy response., PMID:39046874
Tryptophan As a New Member of RNA-Induced Silencing Complexes Prevents Colon Cancer Liver Metastasis., PMID:39031551
Phase Separation Modulates the Thermodynamics and Kinetics of RNA Hybridization., PMID:38991204
Stress Granule Core Protein-Derived Peptides Inhibit Assembly of Stress Granules and Improve Sorafenib Sensitivity in Cancer Cells., PMID:38731625
A delayed decoupling methyl-TROSY pulse sequence for atomic resolution studies of folded proteins and RNAs in condensates., PMID:38626504
Cell cycle associated protein 1 associates with immune infiltration and ferroptosis in gastrointestinal cancer., PMID:38586390
hnRNPA2B1 represses the disassembly of arsenite-induced stress granules and is essential for male fertility., PMID:38363675
Molecular Screening in Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma: Anaplastic Lymphoma Kinase Analysis, Next-Generation Sequencing Fusion Gene Detection, and T-Cell Receptor Immunoprofiling., PMID:38266918
Caprin-1 influences autophagy-induced tumor growth and immune modulation in pancreatic cancer., PMID:38082307
Fear extinction is regulated by the activity of long noncoding RNAs at the synapse., PMID:37993455
Glutamine supplementation alleviated aortic atherosclerosis in mice model and in vitro., PMID:37679095
Exploring the role of m6A methylation regulators in glioblastoma multiforme and their impact on the tumor immune microenvironment., PMID:37606566
Regulation of RNG105/caprin1 dynamics by pathogenic cytoplasmic FUS and TDP-43 in neuronal RNA granules modulates synaptic loss., PMID:37484309
Caprin-1 binding to the critical stress granule protein G3BP1 is influenced by pH., PMID:37161291
Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950., PMID:37082579
CAPRIN1 Is Required for Control of Viral Replication Complexes by Interferon Gamma., PMID:37052473
Expression of GADD45G and CAPRIN1 in Human Nucleus Pulposus: Implications for Intervertebral Disc Degeneration., PMID:36982840
Caprin-1 plays a role in cell proliferation and Warburg metabolism of esophageal carcinoma by regulating METTL3 and WTAP., PMID:36855123
circIPO7 dissociates caprin-1 from ribosomes and inhibits gastric cancer cell proliferation by suppressing EGFR and mTOR., PMID:36732659
The association and clinical relevance of phase-separating protein CAPRIN1 with noncoding RNA., PMID:36627508
STRESS granule-associated RNA-binding protein CAPRIN1 drives cancer progression and regulates treatment response in nasopharyngeal carcinoma., PMID:36515758
Surface electrostatics dictate RNA-binding protein CAPRIN1 condensate concentration and hydrodynamic properties., PMID:36496075
RNA degradation eliminates developmental transcripts during murine embryonic stem cell differentiation via CAPRIN1-XRN2., PMID:36495875
circCAPRIN1 interacts with STAT2 to promote tumor progression and lipid synthesis via upregulating ACC1 expression in colorectal cancer., PMID:36328987
Yin and yang regulation of stress granules by Caprin-1., PMID:36279435
Tryptophan mutations in G3BP1 tune the stability of a cellular signaling hub by weakening transient interactions with Caprin1 and USP10., PMID:36183834
Long noncoding RNA ZNFX1-AS1 promotes the invasion and proliferation of gastric cancer cells by regulating LIN28 and CAPR1N1., PMID:36160641
For research use only. Not for human or drug use.
