Catalog No.
YHH08101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg51-Glu145
Predicted molecular weight
38.66 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q15388
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 5% Trehalose, 2% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Mitochondrial 20 kDa outer membrane protein, Mitochondrial import receptor subunit TOM20 homolog, KIAA0016, TOMM20, Outer mitochondrial membrane receptor Tom20
Note
For research use only.
M133S mutation possibly involve in the ER stress and mitophagy pathway in maintenance hemodialysis patients with occult hepatitis B infection., PMID:38886481
DYRK1A signalling synchronizes the mitochondrial import pathways for metabolic rewiring., PMID:38902238
PGAM5 interacts with and maintains BNIP3 to license cancer-associated muscle wasting., PMID:38919131
Carnosine supplementation in cryopreservation solution improved frozen-thawed bovine embryo viability., PMID:39010149
Spautin-1 promotes PINK1-PRKN-dependent mitophagy and improves associative learning capability in an alzheimer disease animal model., PMID:39051473
Preserving mitochondrial homeostasis protects against drug-induced liver injury via inducing OPTN (optineurin)-dependent Mitophagy., PMID:39099169
Jin-Xin-Kang alleviates heart failure by mitigating mitochondrial dysfunction through the Calcineurin/Dynamin-Related Protein 1 signaling pathway., PMID:39127116
Bunyavirus SFTSV nucleoprotein exploits TUFM-mediated mitophagy to impair antiviral innate immunity., PMID:39189526
Identification of Autophagy-Related Biomarkers and Diagnostic Model in Alzheimer's Disease., PMID:39202387
Sex-dependent regulation of retinal pigment epithelium and retinal function by Pgc-1α., PMID:39285939
Mitochondrial dynamics and sex-specific responses in the developing rat hippocampus: Effect of perinatal asphyxia and mesenchymal stem cell Secretome treatment., PMID:39332539
Mitochondrial disruption resulting from Cepharanthine-mediated TOM inhibition triggers ferroptosis in colorectal cancer cells., PMID:39402386
Selenoprotein M protects cardiac endothelial cell integrity against high-glucose stress via enhancing Parkin-mediated mitophagy., PMID:39454935
Nicotinamide N-oxide Inhibits Microglial Pyroptosis by Upregulating Mitophagy and Alleviates Neural Damage in Rats after TBI., PMID:39472380
STED super-resolution microscopy of mitochondrial translocases., PMID:39488379
TMCO1 regulates energy metabolism and mitochondrial function of hepatocellular carcinoma cells through TOMM20, affecting the growth of subcutaneous graft tumors and infiltration of CAFs., PMID:39566034
Mito-TEMPO Ameliorates Sodium Palmitate Induced Ferroptosis in MIN6 Cells through PINK1/Parkin-Mediated Mitophagy., PMID:39622663
Isoliquiritin targeting m5C RNA methylation improves mitophagy in doxorubicin-induced myocardial cardiotoxicity., PMID:39657405
Endogenous interactomes of MFN1 and MFN2 provide novel insights into interorganelle communication and autophagy., PMID:39675054
Mitochondria-targeted oligomeric α-synuclein induces TOM40 degradation and mitochondrial dysfunction in Parkinson's disease and parkinsonism-dementia of Guam., PMID:39695091
New insights into the role of mitophagy related gene affecting the metastasis of osteosarcoma through scRNA-seq and CRISPR-Cas9 genome editing., PMID:39696352
Aberrant activation of adenine nucleotide translocase 3 promotes progression and chemoresistance in multiple myeloma dependent on PINK1 transport., PMID:39744418
G6PD protects against cerebral ischemia-reperfusion injury by inhibiting excessive mitophagy., PMID:39756510
Reduced expression of the serotonin transporter impacts mitochondria in a sexually dimorphic manner., PMID:39760099
Lactobacillus salivarius metabolite succinate enhances chicken intestinal stem cell activities via the SUCNR1-mitochondria axis., PMID:39764876
Cordycepin alleviates metabolic dysfunction-associated liver disease by restoring mitochondrial homeostasis and reducing oxidative stress via Parkin-mediated mitophagy., PMID:39793718
Twist2 knockdown alleviates renal ischemia-reperfusion injury by maintaining mitochondrial function and enhancing mitophagy through Bnip3., PMID:39918659
TRAF3 loss protects glioblastoma cells from lipid peroxidation and immune elimination via dysregulated lipid metabolism., PMID:39932808
Evaluation of GFM1 mutations pathogenicity through in silico tools, RNA sequencing and mitophagy pahtway in GFM1 knockout cells., PMID:39952508
In situ architecture of the intercellular organelle reservoir between epididymal epithelial cells by volume electron microscopy., PMID:39955273
Sustained release of a novel non-fibrate PPARα agonist from microparticles for neuroprotection in murine models of age-related macular degeneration., PMID:39961437
TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis., PMID:39996379
A mitochondrial outer membrane protein TOMM20 maintains protein stability of androgen receptor and regulates AR transcriptional activity in prostate cancer cells., PMID:40044984
Structure of human PINK1 at a mitochondrial TOM-VDAC array., PMID:40080546
Umbilical cord mesenchymal stem cell-derived extracellular vesicles improve excessive autophagy of granulosa cells through METTL3., PMID:40106233
Identification of a new micropeptide altKLF4 derived from KLF4 that influences myeloma chemotherapeutic sensitivity., PMID:40147548
Inhibition of PINK1 senses ROS signaling to facilitate neuroblastoma cell pyroptosis., PMID:40160153
Targeted activation on Bnip3 enhances mitophagy to prevent the progression of osteoarthritis., PMID:40190344
BNIP3-mediated mitophagy in macrophages regulates obesity-induced adipose tissue metaflammation., PMID:40195021
USP7 promotes PINK1/Parkin-dependent mitophagy to ameliorate cerebral ischemia-reperfusion injury by deubiquitinating and stabilizing SIRT1., PMID:40216374
Role of IP3R2-Mediated mitochondrial calcium homeostasis in early hypoxic stress injury of retinal pigment epithelial cells., PMID:40267840
Progranulin enhances M2 macrophage polarization and renal fibrosis by modulating autophagy in chronic kidney disease., PMID:40293508
Tooth Loss Leads to Cognitive Impairment and Mitochondrial Disturbance in Wistar Rats., PMID:40311189
Integrative proximal-ubiquitomics profiling for deubiquitinase substrate discovery applied to USP30., PMID:40328249
Protective Effects of Rat Bone Marrow Mesenchymal Stem Cells-Derived Fusogenic Plasma Membrane Vesicles Containing VSVG Protein Mediated Mitochondrial Transfer on Myocardial Injury In Vitro., PMID:40330432
NLRP3 inflammasome inhibits mitophagy during the progression of temporal lobe epilepsy., PMID:40348802
Inactivation of SIAH-1 E3 ligase attenuates Aβ toxicity by suppressing ubiquitin-dependent DVE-1 degradation in Caenorhabditis elegans models of Alzheimer's disease., PMID:40349774
Sex-specific loss of mitochondrial membrane integrity in the auditory brainstem of a mouse model of Fragile X Syndrome., PMID:40359994
The activation of cGAS-STING pathway promotes the epithelial-mesenchymal transition and inflammation in intrauterine adhesion., PMID:40409098
[Study on mechanism of naringin in alleviating cerebral ischemia/reperfusion injury based on DRP1/LRRK2/MCU axis]., PMID:40461204
For research use only. Not for human or drug use.
