Catalog No.
PHC20601
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human S100A6 (Met1-Gly90).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Calcyclin,S100A6,S100 calcium-binding protein A6,Protein S100-A6,Prolactin receptor-associated protein,MLN 4,CACY,PRA,Growth factor-inducible protein 2A9
Purification
Purified by antigen affinity column.
Accession
P06703
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Low serum S100A6 levels are associated RP-ILD risk in anti-MDA5-positive dermatomyositis., PMID:39680260
Comparative analysis of electrophoresis and interferometric optical detection method for molecular weight determination of proteins., PMID:39229532
A Pilot Study of a Panel of Ocular Inflammation Biomarkers in Patients with Primary Sjögren's Syndrome., PMID:37185712
S100A6 participates in initiation of autoimmune encephalitis and is under epigenetic control., PMID:36748983
Metal exposure from additive manufacturing and its effect on the nasal lavage fluid proteome - a pilot study., PMID:34464420
Quantification of a panel for dry-eye protein biomarkers in tears: A comparative pilot study using standard ELISA and customized microarrays., PMID:34012227
A novel metastatic promoter CEMIP and its downstream molecular targets and signaling pathway of cellular migration and invasion in SCLC cells based on proteome analysis., PMID:32648226
Changes in tear biomarker levels in keratoconus after corneal collagen crosslinking., PMID:30804658
Tear proteome analysis in ocular surface diseases using label-free LC-MS/MS and multiplexed-microarray biomarker validation., PMID:29234088
Affinity Proteomics Exploration of Melanoma Identifies Proteins in Serum with Associations to T-Stage and Recurrence., PMID:28433799
Discovery of circulating proteins associated to knee radiographic osteoarthritis., PMID:28273936
Differentially Methylated DNA Regions in Monozygotic Twin Pairs Discordant for Rheumatoid Arthritis: An Epigenome-Wide Study., PMID:27909437
Evaluation and screening of mRNA S100A genes as serological biomarkers in different stages of bladder cancer in Egypt., PMID:26508026
Antigen-Antibody Affinity for Dry Eye Biomarkers by Label Free Biosensing. Comparison with the ELISA Technique., PMID:26287192
S100A6 expression in cutaneous smooth muscle neoplasms., PMID:26238340
Localization of S100A2, S100A4, S100A6, S100A7, and S100P in the human hair follicle., PMID:25507257
Localization of S100A2, S100A4, S100A6, S100A7, and S100P in the human hair follicle., PMID:25417529
The receptor for advanced glycation end products influences the expression of its S100 protein ligands in melanoma tumors., PMID:25310905
S100A6 is secreted from Wharton's jelly mesenchymal stem cells and interacts with integrin β1., PMID:25256682
S100A6 and its extracellular targets in Wharton's jelly of healthy and preeclamptic patients., PMID:24746261
Intrinsically disordered and aggregation prone regions underlie β-aggregation in S100 proteins., PMID:24098542
Differentially expressed genes of human microvascular endothelial cells in response to anti-dengue virus NS1 antibodies by suppression subtractive hybridization., PMID:23697814
Ca(2+) /S100 proteins regulate HCV virus NS5A-FKBP8/FKBP38 interaction and HCV virus RNA replication., PMID:23522085
Measuring binding of S100 proteins to RAGE by surface plasmon resonance., PMID:23296613
Upregulation of calcium binding protein, S100A6, in activated astrocytes is linked to glutamate toxicity., PMID:22982625
Immunohistochemical Characterization of S100A6 in the Murine Ovary., PMID:22489100
S100A expression in normal corneal-limbal epithelial cells and ocular surface squamous cell carcinoma tissue., PMID:21897749
Adipocytes derived from human bone marrow mesenchymal stem cells exert inhibitory effects on osteoblastogenesis., PMID:21663588
The stimulation of HSD17B7 expression by estradiol provides a powerful feed-forward mechanism for estradiol biosynthesis in breast cancer cells., PMID:21372145
S100A proteins in the pathogenesis of experimental corneal neovascularization., PMID:21139687
Classic neurothekeoma (nerve sheath myxoma) and cellular neurothekeoma of the oral mucosa: immunohistochemical profiles., PMID:20923450
RAGE and S100 protein transcription levels are highly variable in human melanoma tumors and cells., PMID:20093728
Increased cytoplasmic S100A6 expression is associated with pulmonary adenocarcinoma progression., PMID:19712129
Immunohistochemical expression of S100A6 in cellular neurothekeoma: clinicopathologic and immunohistochemical analysis of 31 cases., PMID:19542912
Calcium-binding S100 protein expression in pterygium., PMID:19223989
Expression of cyclophilin B is associated with malignant progression and regulation of genes implicated in the pathogenesis of breast cancer., PMID:19056847
[S-100 protein positivity in osteogenic tumours and tumour-like bone forming lesions]., PMID:18783135
Tumor expression of S100A6 correlates with survival of patients with stage I non-small-cell lung cancer., PMID:18620780
Differential expression of S100 protein subtypes in malignant melanoma, and benign and malignant peripheral nerve sheath tumors., PMID:18547346
Expression of S100A6 protein in a broad spectrum of cutaneous tumors using tissue microarrays., PMID:18201235
Diagnostic utility of S100P and von Hippel-Lindau gene product (pVHL) in pancreatic adenocarcinoma-with implication of their roles in early tumorigenesis., PMID:18162774
S100B and S100A6 differentially modulate cell survival by interacting with distinct RAGE (receptor for advanced glycation end products) immunoglobulin domains., PMID:17726019
Glomerular crescent-related biomarkers in a murine model of chronic graft versus host disease., PMID:16249193
Aberrantly differentiated cells in benign pilomatrixoma reflect the normal hair follicle: immunohistochemical analysis of Ca-binding S100A2, S100A3 and S100A6 proteins., PMID:15727645
Hair follicle stem cells in the lower bulge form the secondary germ, a biochemically distinct but functionally equivalent progenitor cell population, at the termination of catagen., PMID:15617565
Cellular neurothekeoma with histiocytic differentiation., PMID:15268715
Calcium-regulated interaction of Sgt1 with S100A6 (calcyclin) and other S100 proteins., PMID:12746458
S100A protein expression in the distinction between lentigo maligna and pigmented actinic keratosis., PMID:12652189
Antibody to S100a6 protein is a sensitive immunohistochemical marker for neurothekeoma., PMID:12641790
Expression of members of the S100 Ca2+-binding protein family in guinea-pig smooth muscle., PMID:12526882