Catalog No.
YHK34801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
His41-Ile423
Predicted molecular weight
45.39 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UL52
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DESC1, Serine protease DESC1, Transmembrane protease serine 11E, TMPRSS11E, TMPRSS11E2, Transmembrane protease serine 11E2
Note
For research use only.
Human DESC1 serine protease confers tumorigenic properties to MDCK cells and it is upregulated in tumours of different origin., PMID:17579619
Probing the substrate specificities of matriptase, matriptase-2, hepsin and DESC1 with internally quenched fluorescent peptides., PMID:19302215
Type II transmembrane serine protease (TTSP) deregulation in cancer., PMID:21196187
DESC1 and MSPL activate influenza A viruses and emerging coronaviruses for host cell entry., PMID:25122802
DESC1, a novel tumor suppressor, sensitizes cells to apoptosis by downregulating the EGFR/AKT pathway in esophageal squamous cell carcinoma., PMID:26856390
Identification of hub genes and pathways associated with bladder cancer based on co-expression network analysis., PMID:28693282
LncRNA-TUSC7/miR-224 affected chemotherapy resistance of esophageal squamous cell carcinoma by competitively regulating DESC1., PMID:29530057
Inhibitors of type II transmembrane serine proteases in the treatment of diseases of the respiratory tract - A review of patent literature., PMID:32887532
HDAC8 Activates AKT through Upregulating PLCB1 and Suppressing DESC1 Expression in MEK1/2 Inhibition-Resistant Cells., PMID:34064422
Study of the inhibitory effect of STAT1 on PDCoV infection., PMID:35033844
Elevated expression of the membrane-anchored serine protease TMPRSS11E in NSCLC progression., PMID:35951670
Increased Expression of TMPRSS11E Is Involved in LPS- or Poly(I:C)-mediated Inflammation., PMID:36413750
Construction of a genomic instability-derived predictive prognostic signature for non-small cell lung cancer patients., PMID:37579716
Identification of novel gene signature for lung adenocarcinoma by machine learning to predict immunotherapy and prognosis., PMID:37583701
For research use only. Not for human or drug use.
