Catalog No.
DHJ47101
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG
Clonality
Monoclonal
Target
Tumor susceptibility gene 101 protein, ESCRT-I complex subunit TSG101, TSG101
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q99816
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
FGI-101-1A6, FGI 101 1A6, FGI1011A6
Clone ID
FGI-101-1A6
[Efficient capture and proteomics analysis of urinary extracellular vesicles by affinity purification]., PMID:40331614
[Preparation of hybrid exosomes based on bovine milk exosomes and liposomes and pharmacodynamic study of sinomenine loaded exosomes in treatment of rheumatoid arthritis]., PMID:39307739
Circulating small extracellular vesicles in Alzheimer's disease: a case-control study of neuro-inflammation and synaptic dysfunction., PMID:38902659
Spectroscopic insight into breast cancer: profiling small extracellular vesicles lipids via infrared spectroscopy for diagnostic precision., PMID:38654096
Analysis of the Expression of LSF Transcription Factor in the Regulation of Transcription and TSG101 during the Neoplastic Transformation of Endometrial Cells., PMID:38607019
Deciphering pancreatic neuroendocrine tumors: Unveiling through circulating small extracellular vesicles., PMID:38596136
Preparation of Nanoparticle-Loaded Extracellular Vesicles Using Direct Flow Filtration., PMID:37242792
Cardiomyocyte-targeting exosomes from sulforaphane-treated fibroblasts affords cardioprotection in infarcted rats., PMID:37161563
Regulation of c-SMAC formation and AKT-mTOR signaling by the TSG101-IFT20 axis in CD4+ T cells., PMID:37029318
A Rapid, Convergent Approach to the Identification of Exosome Inhibitors in Breast Cancer Models., PMID:36593796
Significance of Mannan Binding Lectin-Associated Serine Protease 2 in Urinary Extracellular Vesicles in IgA Nephropathy., PMID:36149051
Isolation and analysis of tumor‑derived extracellular vesicles from head and neck squamous cell carcinoma plasma by galectin‑based glycan recognition particles., PMID:36129151
Profiling of extracellular vesicles of metastatic urothelial cancer patients to discover protein signatures related to treatment outcome., PMID:35838333
EhVps23, an ESCRT-I Member, Is a Key Factor in Secretion, Motility, Phagocytosis and Tissue Invasion by Entamoeba histolytica., PMID:35360117
Epstein-Barr Virus Enhances Cancer-Specific Aberrant Splicing of TSG101 Pre-mRNA., PMID:35269659
Column-based Technology for CD9-HPLC Immunoaffinity Isolation of Serum Extracellular Vesicles., PMID:34473505
Simultaneous Isolation of Circulating Nucleic Acids and EV-Associated Protein Biomarkers From Unprocessed Plasma Using an AC Electrokinetics-Based Platform., PMID:33224932
An inverted CAV1 (caveolin 1) topology defines novel autophagy-dependent exosome secretion from prostate cancer cells., PMID:32897127
Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation., PMID:31959764
Fast isolation of highly specific population of platelet-derived extracellular vesicles from blood plasma by affinity monolithic column, immobilized with anti-human CD61 antibody., PMID:31679569
Tumour-Secreted Hsp90α on External Surface of Exosomes Mediates Tumour - Stromal Cell Communication via Autocrine and Paracrine Mechanisms., PMID:31641193
Proteome Profiling of Exosomes Purified from a Small Amount of Human Serum: The Problem of Co-Purified Serum Components., PMID:31035355
Pancreatic Juice Exosomal MicroRNAs as Biomarkers for Detection of Pancreatic Ductal Adenocarcinoma., PMID:30820789
Extracellular Vesicles from Wharton's Jelly Mesenchymal Stem Cells Suppress CD4 Expressing T Cells Through Transforming Growth Factor Beta and Adenosine Signaling in a Canine Model., PMID:30412034
Tumor-Derived Exosomal Long Noncoding RNAs as Promising Diagnostic Biomarkers for Prostate Cancer., PMID:29614511
TSG101: Tumor Susceptibility Gene 101 (tsg101) Product-Role in Therapy Against HIV/AIDS., PMID:29199609
ESCRT-I Protein Tsg101 Plays a Role in the Post-macropinocytic Trafficking and Infection of Endothelial Cells by Kaposi's Sarcoma-Associated Herpesvirus., PMID:27764233
Integrin signaling via FAK-Src controls cytokinetic abscission by decelerating PLK1 degradation and subsequent recruitment of CEP55 at the midbody., PMID:27127172
ESCRT (Endosomal Sorting Complex Required for Transport) Machinery Is Essential for Acrosomal Exocytosis in Human Sperm., PMID:26490837
Bacterial genotoxins promote inside-out integrin β1 activation, formation of focal adhesion complexes and cell spreading., PMID:25874996
A protocol for exosome isolation and characterization: evaluation of ultracentrifugation, density-gradient separation, and immunoaffinity capture methods., PMID:25820723
Nedd4-mediated increase in HIV-1 Gag and Env proteins and immunity following DNA-vaccination of BALB/c mice., PMID:24614057
Polarized release of T-cell-receptor-enriched microvesicles at the immunological synapse., PMID:24487619
Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans-Golgi network., PMID:22711829
ALIX binds a YPX(3)L motif of the GPCR PAR1 and mediates ubiquitin-independent ESCRT-III/MVB sorting., PMID:22547407
TSG101 exposure on the surface of HIV-1 infected cells: implications for monoclonal antibody therapy for HIV/AIDS., PMID:20733947
The nucleocapsid region of HIV-1 Gag cooperates with the PTAP and LYPXnL late domains to recruit the cellular machinery necessary for viral budding., PMID:19282983
[The Relationship between TSG101 Protein and Notch3 Receptor in Lung Cancer.]., PMID:20716402
Fully in vitro selection of recombinant antibodies., PMID:19156724
Molecular characterization of feline immunodeficiency virus budding., PMID:18094166
HD-PTP and Alix share some membrane-traffic related proteins that interact with their Bro1 domains or proline-rich regions., PMID:17174262
Role of the human T-cell leukemia virus type 1 PTAP motif in Gag targeting and particle release., PMID:16537631
Elevated expression of C10orf3 (chromosome 10 open reading frame 3) is involved in the growth of human colon tumor., PMID:16170351
SIMPLE interacts with NEDD4 and TSG101: evidence for a role in lysosomal sorting and implications for Charcot-Marie-Tooth disease., PMID:16118794
Tumour-derived exosomes and their role in cancer-associated T-cell signalling defects., PMID:15655551
Tal, a Tsg101-specific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus budding., PMID:15256501
Physical and functional interactions between Daxx and TSG101., PMID:15033475
Overexpression of tumor susceptibility gene TSG101 in human papillary thyroid carcinomas., PMID:12101421
Mammalian class E vps proteins recognize ubiquitin and act in the removal of endosomal protein-ubiquitin conjugates., PMID:11916981
Perturbation of TSG101 protein affects cell cycle progression., PMID:9661875
For research use only. Not for human or drug use.
